STUDY GUIDE Flashcards
Thalamus
“Relay Station” Gateway of the cortex - Receives Auditory, Somatosensory & Visual Signals • Relays Sensory Signals to the Cerebral Cortex
Hypothalamus
Autonomic Function
• Activates sympathetic nervous system, body temp, osmolarity, reprod, food intake
• Interacts with limbic system to influence behavior and emotions
• Influences cardiovascular control center in medulla oblongata
• Secretes trophic hormones that control release of hormones from anterior pituitary gland
Medulla Oblongata
Regulation of cardiac and respiratory function, sleep, eating, consciousness
The Limbic System
- Emotion, memory, and learning. Primitive brain – necessary for survival
• Control of functions necessary for self preservation and species preservation (fear, anger, eating, sex)
• Regulate autonomic and endocrine function, particularly in response to emotional stimuli
• Cingulate gyrus, Amgdyla
Sensation
bottom-up processing, sensory receptors receive and relay outside stimuli
Perception
top-down processing, brain organizes and interprets information, puts into context
(depends on sensory input and physiological state (e.g., alertness)
Somatic Sensory system
specific receptor structures, intracellular amplification of signal
Somatic Sensory system
Sensory Coding
Sense organs are filters – highly selective and sensitive to specific types of stim
Somatic Sensory system
Simple receptor
neurons with free nerve endings (somatosensory)
Somatic Sensory system
Specialized sense receptors
non-neural. Release NT onto sensory neurons
Somatic Sensory system
Complex receptor
nerve endings enclosed in connective tissue capsules
Somatic Sensory system
Transduction
stimulus energy transformed into neural electrical activity
Each sensory receptor cell transduces a particular form of stimulus into a membrane current that changes the membrane potential of that cell (graded potentials
Graded potentials
changes in membrane potential that vary in size, as opposed to being all-or-none
• Tend to occur in dendrites or soma of neuron
• Size and duration dependent on size and duration of stimulus
• Arise from the summation of the individual actions of ligand-gated ion channel proteins, and decrease
over time and space
• They do not typically involve voltage-gated sodium and potassium channels
• Decay with time and distance
Spatial and Temporal Summation
adaptation
Adaptation
Reduction in sensitivity due to a constant stimulus, Peripheral and Central adaptation
Topographical organization
point to point representation of a sensory surface in the brain
• Somatotopy
• Size of sensory input due to density of input and importance (index finger more important than elbow)
Somatic Senses
touch, proprioception, temperature, nociception - different than other senses
• Receptors are widely distributed throughout body
• Receptors respond to different stimuli (touch, temp, pain, body position)
• 3 sensations detected by skin
• Mechanoreceptors - Vibration, soft touch, pressure (skin, bv’s, organs)
• Thermoreceptors - Temperature
• Nociceptors - Pain: mechanical, chemical, thermal
Mechanically gated ion channels
Vibration/touch information in separate pathway from pain/temp
Receptive Fields
vary in size (smaller receptive fields = greater acuity (two-point discrimination))
• Higher density of mechanoreceptors on fingertip (small receptive fields) - more brain tissue devoted to each square mm of fingertip
• Character of receptive field changes as it passes through pathway
• Neurons respond to separate aspects of stimuli (shape, size, texture) but then combine them (within
and between different senses) to identify objects
Dermatomes
an area of skin that is mainly supplied by a single spinal nerve
• Damage to single dorsal root ganglion - sensation is not usually lost in that dermatome because of overlapping segments
Shingles
Herpes zoster virus reactivated in neurons of a single dorsal root ganglion – leads to increased excitability in sensory neurons, spontaneous firing
Referred pain
Multiple nociceptors from different regions converge on the same ascending tract in the spinal cord, Somatic pain is more common than visceral pain so brain interprets signals from viscera as skin pain
Agnosia
Occurs with damage to posterior parietal cortex
• Astereoagnosia (tactile agnosia) – cannot recognize common objects by feeling them
Phantom limbs
Somatosensory cortex undergoes substantial reorganization after the loss of input
• Mirror training
Touch vs. Pain pathways
Modulation of pain
Vision
Stimuli = Light , Electromagnetic radiation visible to our eyes (Wavelength, frequency, amplitude)
– Light enters the eye - Focused on retina by the lens
– Photoreceptors transduce light energy - Electrical signal – Electrical signal -Processed through neural pathways
Light is focused on retina by Refraction - Bending of light rays from one medium to another
– Cornea collects and bends light so it converges on back of eye
– Focal Distance – distance from reflective surface to retina