Study as I go Flashcards
Penton fibers?
Adenoviridae
Penton fibers cause what?
Hemagglutination of RBCs
How are adenoviruses released inside the host?
Cell lysis
Infectious Canine Hepatitis?
Canine Adenovirus 1
Why is Infectious Canine Hepatitis so infectious?
Shed in urine for 6 months
Pathognomonic characteristic of early Infectious Canine Hepatitis?
Corneal Edema/Blue eye
Kennel Cough/Infectious Tracheobronchitis
CAV-2
What breed is most susceptible to Equine Adenovirus?
Arabian Foals
Outcome of Equine adenovirus?
Bronchitis and Pneumonia
Death before 3m
How does retroviridae spread in the host?
Type 3
Bovine Leukemia
Deltaretrovirus
What cell does bovine leukemia target?
B lymphocytes
Important proteins for Bovine Leukemia?
gp51
p24 (Major Core)
Number one cause of carcass condemnation in cattle?
Bovine Leukemia
FeLV?
Gammaretrovirus
Important protein in FeLV
p27
Target cells of FeLV?
T and B
Horizontally transmitted FeLV?
FeLV-A
Cats with that FeLV have a higher risk of tumors?
A and B
How do cats get FeLV-C?
mutation
How soon after having an FeLV + cat can a new one be introduced to the home?
3-4w
Antigen present on all membranes of cells transformed by FeLV and FeSV?
FOCMA
Recombination of FeLVA and host proto-oncogenes?
FeSV
Cause of fibrosarcomas in cats?
FeSV
Avian leukosis
Alpharetrovirus
What birds are affected by avian leukosis?
Chickens only
Target cell of avian leukosis?
B
Thick leg in birds?
Osteoporosis from avian leukosis
How can you differentiate Avian Leukosis from Marek’s Dz?
No nerve or ocular involvement in AL
FIV?
Feline lentivirus
How is FIV transmitted?
Bites, Milk, TP
What cell does FIV target?
CD4
Important antigen in FIV?
p24
Retrovirus with no cross protection between serotypes?
FIV
Equine Infectious Anemia/Swamp Fever
Equine lentivirus
Reportable retrovirus?
Equine lentivirus
Vector of Equine lentivirus?
Tabanids (mechanical)
Test of Equine lentivirus?
Coggins test
Coggins test is for what protein?
p26
Caprine Arthritis Encephalomyelitis
Caprine lentivirus
Most important goat disease in the US?
Caprine lentivirus
Big knee?
Caprine lentivirus
Hard bag?
Mastitis from caprine lentivirus and ovine lentivirus
Can colostrum be used from CAEV+ goats?
Yes, pasturize
Maedi-visna
Ovine lentivirus
Maedi?
Lungs
Visna?
Brain
Incubation period for ovine lentivirus?
up to 9 years!!
Symptom of Maedi?
Pneumonia
Symptom of Visna?
CNS, knuckling of fetlock
Bullet shaped virus?
Rhabdo
Rabies?
lyssavirus
vesicular stomatitits
vesiculovirus
defecting interfering particles are found in what virus?
rhabdo
most lethal infectious disease?
rabies
which rabies genotype is the classic one?
Genotype 1
What species perpetuates cattle rabies?
Skunks
What species perpetuates human and non-cattle rabies?
Vampire Bats
How does Rabies reach the brain?
Centripetal progress
Furious form of rabies replication?
Limbic system
Dumb form of rabies replication?
Neocortex
How does rabies reach the salivary glands?
Centrifugal progress
Why do animals die from rabies?
Respiratory failure
Which species has viremia and a carrier state for vesicular stomatitis?
Pigs
What disease looks just like vesicular stomatitis?
Foot and mouth
Characteristic clinical feature of vesicular stomatitis?
Profuse salivation
Immunity for vesicular stomatitis?
Short lived
3 day sickness?
Bovine ephemerovirus
Vector of bovine ephemerovirus?
Mosquitos
Culicoides
Foot and mouth disease?
Apthovirus
Avian encephalomyelitis
Avian tremovirus
Encephalomyocarditis
Cardiovirus
What species are affected by foot and mouth disease?
All cloven hoofed animals
How long are cattle carriers for foot and mouth?
2yr
How long are sheep carriers for foot and mouth?
6m
What animal is not a carrier for foot and mouth?
Pigs
When does shedding of foot and mouth begin?
24hr before clinical signs
Amplifying host for foot and mouth?
Swine
Tiger heart?
foot and mouth
How does foot and mouth cause abortion?
Fever! Doesn’t cross placenta
Key clinical sign for foot and mouth?
profuse salivation
How is foot and mouth transmitted?
Aerosol
What species are affected by encephalomyocarditis?
Piglets
Reservoir for encephalomyocarditis?
Rodents
Clinical feature of encephalomyocarditis?
SMEDI
Pathognomonic for encephalomyocarditis?
Myocardial infarcts and necrosis
Is vesicular stomatitis more often transmitted by mechanical or biological?
Mechanical
Reportable Rhabdoviridaes?
Rabies, Vesicular Stomatitis, Bovine Ephemeral Fever (so ALL!)
Why are horse owners cautioned about vaccinated for vesicular stomatitis?
Can’t differentiate vaccine from natural exposure
Zoonotic Rhabdos?
Rabies and Vesicular Stomatitis
Which rhabdo does not have cross protection?
Vesicular Stomatitis
What rhabdo is not in NA?
Bovine ephemeral fever
Are picornas stable?
In mucus, feces
Where is Foot and Mouth disease not found?
NA, CA, Oceania, Carib
What species is genetically resistant to FMD?
Horses
Can animals be reinfected with FMD?
Yes, no cross protection
Is FMD stable?
Very! 2-3 weeks! (not in carcass though, disinfectants work)
Transmission of FMD?
Inhalation, Uncooked meat
Why is FMD so worrisome for transportation?
Asymptomatic carriers
Reportable Picorna viruses?
FMD
What birds are most often affected by avian encephalomyelitis?
Chicks
What protein in Paramyxo neutralizes antibodies?
H
What protein in Paramyxo destroys mucin inhibitors?
N
What protein in Paramyxo helps with Type 3 spread?
F
Most important avian disease?
Newcastle
Which paramyxos have H and N proteins?
BPI-3, Newcastle
Which protein does canine distemper not have?
N
Inclusion bodies in Paramyxo?
Red, IN/IC
Shipping fever associated paramyxo viruses?
Bovine Parainfluenza
Bovine Respiratory Syncytial Disease
Newcastle Disease?
Avian paramyxovirus 1
Avirulent strain of newcastle disease?
lentogenic
What enzyme does the lentogenic newcastle use?
Trypsin
Virulent strains of ND use what enzyme?
endoprotease
Moderately virulent ND strain?
Mesogenic
Highly virulent ND strain?
Velogenic
When is ND shed?
before during and after symptoms!
What form of ND affects the intestines rather than the respiratory tract?
Viscerotropic Velogenic ND
Which forms of ND have high mortality?
Viscerotropic and Neurotropic Velogenic
Kennel cough paramyxo?
Canine Parainfluenza Virus 5
Canine distemper?
Canine morbillibirus