Final Exam Flashcards
Where does Adenovirus replicate?
Nucleus
How is Adenovirus released?
Lysis
Does Adenovirus have an envelope?
No
Rubarth’s Disease?
Infectious Canine Hepatitis
Etiology of Infectious Canine Hepatitis?
Canine Adenovirus 1
Virus that is shed for 6+ months after infection in urine?
Infectious Canine Hepatitis
Causes corneal edema/blue eye?
Infectious Canine Hepatitis
Infectious Canine Hepatitis first infects what part of the body?
Tonsillar crypts and Peyer’s patches
Does Infectious Canine Hepatitis cause viremia?
Yes in MOs
Type 3 hypersensitivity in infectious canine hepatitis causes what?
Glomerulonephritis
Enodthelial damage from Infectious Canine Hepatitis causes what?
DIC
What antibody titer shows immunity to Infectious Canine Hepatitis?
1:4
Kennel cough?
Canine infectious tracheobronchitis
Canine infectious tracheobronchitis etiology?
Canine adenovirus 2
Equine adenovirus infections etiology?
Equine adenovirus 1
Equine adenovirus infections kills what breed within 3 months?
SCID Arabian foals
The penton tips of Adenovirus cause what in blood?
Agglutinate RBCs
Which type of adenovirus has bifurcated pentane fibers?
Aviadenovirus
RNA virus that has own transcriptase?
Retro
V-onc that is defective and can’t replicate?
V-onc +
V-onc that integrate into host genome and replicate?
V-onc -
Non oncogenic Retroviruses?
Lentivirus
Etiology for bovine leukemia?
Deltaretrovirus
Deltavirus is V-onc?
Negative
Target cell of delta virus?
B lymphocytes
Deltaretrovirus can cause lymphosarcoma in what aged cattle?
4-8y
Sporadic bovine leukosis affects what aged cattle?
< 3y
Transmission of bovine leukemia
Lymphocytes
Transmission of sporadic bovine leukosis?
Lymphocytes
What retrovirus causes non infectious lymphosarcoma?
Sporadic bovine leukosis
Feline leukemia and sarcoma etiology?
Gammaretrovirus
Gammaretrovirus is v-onc?
Negative
FeLV-A is constantly shed in what fluid?
Saliva
Mutated form of FeLV?
C
FeLV-B is from the recombination of what?
FeLV-A env gene and proviral DNA
Cats with what FeLV are at a higher risk of tumor formation?
BOTH A and B together
How are cats exposed to FeLV?
oronasal
What cells does FeLV replicated in?
T/B lymphocytes
ELISA detects FeLV when?
Transient viremia
IFA detects FeLV when?
secondary viremia
The self-limiting form of FeLV is due to what?
FOCMA
Neoplastic FeLV forms what?
lymphosarcomas
Non-neoplastic FeLV forms what?
Immune xomplexes (vasculitis)
Feline sarcoma virus is caused by what?
FeLV-A recombination with v-onc+
Avian leukosis etiology?
Alpharetrovirus
Alpharetrovirus is v-onc?
Negative
Avian leukosis affects what cell?
B lymphocytes
Avian leukosis-Big liver/visceral lymphomatosis?
Lympohoid leukosis
Avian leukosis-thick leg?
Osteopetrosis
Feline immunodeficiency disease?
Feline lentivirus
FIV targets what cells?
Helper T
Equine infectious anemia?
Equine lentivirus
Swamp fever?
Equine infectious anemia
Viremia type for equine lentivirus?
Lifelong
Caprine arthritis encephalomyelitis
Caprine lentivirus
Goats over 12 months with caprine lentivirus get what form?
polyarthritis
Kids under 5 months get what type of caprine lentivirus?
Encephalomyelitis
Adult goats get what form of caprine lentivirus?
interstitial pneumonia
Lentivirus that can cause mastitis?
caprine
Maedi/Visna disease?
Ovine lentivirus
Type of viremia with made/visna?
Lifelong
shortness of breath lentivirus?
Maedi
wasting lentivirus?
visna
Incubation period of made/visna
months-years
What does reo stand for?
Respiratory Enteric Orphan
What is unique about reovirus capsid?
3 layers
Where does reovirus replicate?
Cytoplasm
Can reo reassort?
Yes
Blue tongue?
Ovine orbivirus
Hosts of blue tongue?
Mostly sheep, but all ruminants
Other names for blue tongue?
Foot and mouth, pseudo foot and mouth, ovine catarhall fever, muzzle disease
Vector of blue tongue?
Culicoides
Is blue tongue reportable?
Yes! List A
What does blue tongue damage?
Vascular endothelium
Clinical signs of blue tongue?
Cyanosis, salivation, mucopurulent discharge
Vaccine for blue tongue?
Yes- attenuated
African horse sickness?
Equine orbivirus
What reovirus is not in NA?
african horse sickness
Vector of african horse sickness?
Culicoides
Acute pulmonary horse sickness?
Dunkop
Subacute cardiac horsesickness?
Dikkop
Clinical signs of african horse sickness?
Edema, hydropericardium/peritoneum, petechiae, froth discharge
Severe diarrhea in young?
Rotavirus- Group A
Target of the Rotavirus vaccine?
VP7, VP4
Transmission of Rotavirus?
fecal oral
Replication of rotavirus?
Mature enterocytes of upper SI
Vaccine for rotavirus?
Cattle and equine
Is rotavirus zoonotic?
Yes
Arthritis in poultry?
Avian reovirus
Transmission of avian reovirus?
fecal oral
Enveloped virus with spikes?
Corona
What does Corona bud through?
ER
Porcine Coronaviruse(s)
Transmissible Gastroenteritis of Pigs
Porcine Epidemic Diarrhea
Porcine Hemagglutinating Encephalomyelitis
Is Transmissible Gastroenteritis List A or B?
B
Which form of Transmissible Gastroenteritis is more severe?
Epidemic form
Incubation of Transmissible Gastroenteritis?
SUDDEN! 1-2 days
Vaccine for Transmissible Gastroenteritis?
Yes-vaccinate pregnant sows and neonates
Where is Porcine Epidemic Diarrhea?
Asia
Vomiting and Wasting disease of pigs?
Porcine Hemagglutinating Encephalomyelitis
Transmission of Porcine Hemagglutinating Encephalomyelitis ?
Aerosol!
Why is Porcine Hemagglutinating Encephalomyelitis wasting disease?
Brain affected->vomiting->malnutrition
What season is bovine coronavirus common during?
Winter
What type of cow is affected by Winter Dystentery?
Recently lactating
What percent of infected cats develop FIP?
1-3%
Effusive form of FIP?
Wet
Test for FIP?
Rivalta test
Important protein in Avian Infectious Bronchitis?
S protein
Some serotypes of Avian Infectious Bronchitis offer cross protection, called?
Protectotypes
What organs does Avian Infectious Bronchitis?
Respiratory
Doughnut shaped capsule?
Torovirus
Breda virus?
Bovine torovirus
Vector of togavirus?
Mosquitos
Important envelope protein in Togaviruses?
E protein
Reservoir for EEEV?
Bird, rodent, reptile
Countries affected by the most virulent EEEV?
NA, Caribbean
Dead end host for EEEv?
Horses, Humans
Condition caused by EEEV?
Encephalomyelitis
Which virus is formed by the recombination of EEEV?
WEEV
Which EEV is more severe, east or west?
Eastern
Reservoir for WEEV?
Birds, Rodents
Amplifier for epizootic VEEV?
Horse
Amplifier for enzootic for WEEV?
Rodent
Which strain of VEEV is more virulent?
Epizootic/Epidemic
Dead end host for enzootic VEEV?
Horse, Humans
Dead end host for epizootic VEEV?
Humans
Vaccines are available for horses for what EEV?
East, West (yearly), VEEV (tissue vaccine)
Vaccines are available for humans for what EEV?
VEEV- only military/lab workers
EEEV enzootic vector?
Culiseta melanura
WEEV enzootic vector?
Culex
WEEV epizootic vector?
Aedes
VEEV vector?
Culex
Bovine Viral Diarrhea Virus?
Pestivirus (flaviviridae)
Mucosal disease is in which BVD?
Cytopathogenic
Difference between cytopathogenic and noncytopathogenic BVD?
Cleavage of NS2-3 (cleaved in cyto)
Which type of BVD is more common?
Type 1
Do both types of BVD have ncp and cp?
Yes
How is BVD spread to calves?
TP
Infection of the fetus with BVD at 1 month results in what?
Embryo death
Infection of the fetus with BVD at 2-4 months results in what?
Persistent Infection Calf
Infection of fetus with BVD after 5 months results in what?
Abortion
Deformities
Normal calf
(depends on age)
Can non-pregnant cows spread BVD?
Yes! (secretions)
Pestivirus in swine?
Hog Cholera/Classical Swine Fever
Different clinical signs in African/Classical Swine Fever
Present the same
What Pestivirus is reportable?
Classical Swine Fever (List A)
Where is Classical Swine Fever?
SA, Asia, Japan, Korea
How is Classical Swine Fever transmitted?
All ways!
Pathognomonic symptoms for Classical Swine Fever?
Turkey Egg Kidney
Button Ulcer Colon
Diva Vaccine?
Classical Swine Fever
Vector of Louping Ill?
Ixodes
Where is Louping Ill?
Europe
Cup shaped depressions?
Calici
How is FCV spread?
Carriers, Recovered, Infected cats all can spread!
-Oronasal secretions
What organs does FCV most often affect?
Oral Cavity
Respiratory Tract
FCV affecting the joints?
Limping Syndrome
Calicivirus that looks like foot and mouth disease?
Vesicular Exanthema of Swine
Virus infecting sea lions in CA?
Vesicular Exanthema of Swine (calici)
Etiology of Infectious Bursal Disease?
Avibirnavirus
Gumboro Disease
Avibirnavirus
Which serotype of Avibirnavirus in symptomatic?
Serotype 1
Transmission of Avibirnavirus?
Fecal Oral
