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Virology > Final Exam > Flashcards

Final Exam Flashcards

1
Q

Where does Adenovirus replicate?

A

Nucleus

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2
Q

How is Adenovirus released?

A

Lysis

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3
Q

Does Adenovirus have an envelope?

A

No

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4
Q

Rubarth’s Disease?

A

Infectious Canine Hepatitis

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5
Q

Etiology of Infectious Canine Hepatitis?

A

Canine Adenovirus 1

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6
Q

Virus that is shed for 6+ months after infection in urine?

A

Infectious Canine Hepatitis

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7
Q

Causes corneal edema/blue eye?

A

Infectious Canine Hepatitis

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8
Q

Infectious Canine Hepatitis first infects what part of the body?

A

Tonsillar crypts and Peyer’s patches

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9
Q

Does Infectious Canine Hepatitis cause viremia?

A

Yes in MOs

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10
Q

Type 3 hypersensitivity in infectious canine hepatitis causes what?

A

Glomerulonephritis

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11
Q

Enodthelial damage from Infectious Canine Hepatitis causes what?

A

DIC

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12
Q

What antibody titer shows immunity to Infectious Canine Hepatitis?

A

1:4

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13
Q

Kennel cough?

A

Canine infectious tracheobronchitis

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14
Q

Canine infectious tracheobronchitis etiology?

A

Canine adenovirus 2

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15
Q

Equine adenovirus infections etiology?

A

Equine adenovirus 1

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16
Q

Equine adenovirus infections kills what breed within 3 months?

A

SCID Arabian foals

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17
Q

The penton tips of Adenovirus cause what in blood?

A

Agglutinate RBCs

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18
Q

Which type of adenovirus has bifurcated pentane fibers?

A

Aviadenovirus

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19
Q

RNA virus that has own transcriptase?

A

Retro

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20
Q

V-onc that is defective and can’t replicate?

A

V-onc +

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21
Q

V-onc that integrate into host genome and replicate?

A

V-onc -

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22
Q

Non oncogenic Retroviruses?

A

Lentivirus

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23
Q

Etiology for bovine leukemia?

A

Deltaretrovirus

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24
Q

Deltavirus is V-onc?

A

Negative

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25
Q

Target cell of delta virus?

A

B lymphocytes

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26
Q

Deltaretrovirus can cause lymphosarcoma in what aged cattle?

A

4-8y

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27
Q

Sporadic bovine leukosis affects what aged cattle?

A

< 3y

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28
Q

Transmission of bovine leukemia

A

Lymphocytes

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29
Q

Transmission of sporadic bovine leukosis?

A

Lymphocytes

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30
Q

What retrovirus causes non infectious lymphosarcoma?

A

Sporadic bovine leukosis

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31
Q

Feline leukemia and sarcoma etiology?

A

Gammaretrovirus

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32
Q

Gammaretrovirus is v-onc?

A

Negative

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33
Q

FeLV-A is constantly shed in what fluid?

A

Saliva

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34
Q

Mutated form of FeLV?

A

C

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35
Q

FeLV-B is from the recombination of what?

A

FeLV-A env gene and proviral DNA

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36
Q

Cats with what FeLV are at a higher risk of tumor formation?

A

BOTH A and B together

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37
Q

How are cats exposed to FeLV?

A

oronasal

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38
Q

What cells does FeLV replicated in?

A

T/B lymphocytes

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39
Q

ELISA detects FeLV when?

A

Transient viremia

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40
Q

IFA detects FeLV when?

A

secondary viremia

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41
Q

The self-limiting form of FeLV is due to what?

A

FOCMA

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42
Q

Neoplastic FeLV forms what?

A

lymphosarcomas

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43
Q

Non-neoplastic FeLV forms what?

A

Immune xomplexes (vasculitis)

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44
Q

Feline sarcoma virus is caused by what?

A

FeLV-A recombination with v-onc+

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45
Q

Avian leukosis etiology?

A

Alpharetrovirus

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46
Q

Alpharetrovirus is v-onc?

A

Negative

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47
Q

Avian leukosis affects what cell?

A

B lymphocytes

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48
Q

Avian leukosis-Big liver/visceral lymphomatosis?

A

Lympohoid leukosis

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49
Q

Avian leukosis-thick leg?

A

Osteopetrosis

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50
Q

Feline immunodeficiency disease?

A

Feline lentivirus

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51
Q

FIV targets what cells?

A

Helper T

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52
Q

Equine infectious anemia?

A

Equine lentivirus

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53
Q

Swamp fever?

A

Equine infectious anemia

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54
Q

Viremia type for equine lentivirus?

A

Lifelong

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55
Q

Caprine arthritis encephalomyelitis

A

Caprine lentivirus

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56
Q

Goats over 12 months with caprine lentivirus get what form?

A

polyarthritis

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57
Q

Kids under 5 months get what type of caprine lentivirus?

A

Encephalomyelitis

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58
Q

Adult goats get what form of caprine lentivirus?

A

interstitial pneumonia

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59
Q

Lentivirus that can cause mastitis?

A

caprine

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60
Q

Maedi/Visna disease?

A

Ovine lentivirus

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61
Q

Type of viremia with made/visna?

A

Lifelong

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62
Q

shortness of breath lentivirus?

A

Maedi

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63
Q

wasting lentivirus?

A

visna

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64
Q

Incubation period of made/visna

A

months-years

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65
Q

What does reo stand for?

A

Respiratory Enteric Orphan

66
Q

What is unique about reovirus capsid?

A

3 layers

67
Q

Where does reovirus replicate?

A

Cytoplasm

68
Q

Can reo reassort?

A

Yes

69
Q

Blue tongue?

A

Ovine orbivirus

70
Q

Hosts of blue tongue?

A

Mostly sheep, but all ruminants

71
Q

Other names for blue tongue?

A

Foot and mouth, pseudo foot and mouth, ovine catarhall fever, muzzle disease

72
Q

Vector of blue tongue?

A

Culicoides

73
Q

Is blue tongue reportable?

A

Yes! List A

74
Q

What does blue tongue damage?

A

Vascular endothelium

75
Q

Clinical signs of blue tongue?

A

Cyanosis, salivation, mucopurulent discharge

76
Q

Vaccine for blue tongue?

A

Yes- attenuated

77
Q

African horse sickness?

A

Equine orbivirus

78
Q

What reovirus is not in NA?

A

african horse sickness

79
Q

Vector of african horse sickness?

A

Culicoides

80
Q

Acute pulmonary horse sickness?

A

Dunkop

81
Q

Subacute cardiac horsesickness?

A

Dikkop

82
Q

Clinical signs of african horse sickness?

A

Edema, hydropericardium/peritoneum, petechiae, froth discharge

83
Q

Severe diarrhea in young?

A

Rotavirus- Group A

84
Q

Target of the Rotavirus vaccine?

A

VP7, VP4

85
Q

Transmission of Rotavirus?

A

fecal oral

86
Q

Replication of rotavirus?

A

Mature enterocytes of upper SI

87
Q

Vaccine for rotavirus?

A

Cattle and equine

88
Q

Is rotavirus zoonotic?

A

Yes

89
Q

Arthritis in poultry?

A

Avian reovirus

90
Q

Transmission of avian reovirus?

A

fecal oral

91
Q

Enveloped virus with spikes?

A

Corona

92
Q

What does Corona bud through?

A

ER

93
Q

Porcine Coronaviruse(s)

A

Transmissible Gastroenteritis of Pigs
Porcine Epidemic Diarrhea
Porcine Hemagglutinating Encephalomyelitis

94
Q

Is Transmissible Gastroenteritis List A or B?

A

B

95
Q

Which form of Transmissible Gastroenteritis is more severe?

A

Epidemic form

96
Q

Incubation of Transmissible Gastroenteritis?

A

SUDDEN! 1-2 days

97
Q

Vaccine for Transmissible Gastroenteritis?

A

Yes-vaccinate pregnant sows and neonates

98
Q

Where is Porcine Epidemic Diarrhea?

A

Asia

99
Q

Vomiting and Wasting disease of pigs?

A

Porcine Hemagglutinating Encephalomyelitis

100
Q

Transmission of Porcine Hemagglutinating Encephalomyelitis ?

A

Aerosol!

101
Q

Why is Porcine Hemagglutinating Encephalomyelitis wasting disease?

A

Brain affected->vomiting->malnutrition

102
Q

What season is bovine coronavirus common during?

A

Winter

103
Q

What type of cow is affected by Winter Dystentery?

A

Recently lactating

104
Q

What percent of infected cats develop FIP?

A

1-3%

105
Q

Effusive form of FIP?

A

Wet

106
Q

Test for FIP?

A

Rivalta test

107
Q

Important protein in Avian Infectious Bronchitis?

A

S protein

108
Q

Some serotypes of Avian Infectious Bronchitis offer cross protection, called?

A

Protectotypes

109
Q

What organs does Avian Infectious Bronchitis?

A

Respiratory

110
Q

Doughnut shaped capsule?

A

Torovirus

111
Q

Breda virus?

A

Bovine torovirus

112
Q

Vector of togavirus?

A

Mosquitos

113
Q

Important envelope protein in Togaviruses?

A

E protein

114
Q

Reservoir for EEEV?

A

Bird, rodent, reptile

115
Q

Countries affected by the most virulent EEEV?

A

NA, Caribbean

116
Q

Dead end host for EEEv?

A

Horses, Humans

117
Q

Condition caused by EEEV?

A

Encephalomyelitis

118
Q

Which virus is formed by the recombination of EEEV?

A

WEEV

119
Q

Which EEV is more severe, east or west?

A

Eastern

120
Q

Reservoir for WEEV?

A

Birds, Rodents

121
Q

Amplifier for epizootic VEEV?

A

Horse

122
Q

Amplifier for enzootic for WEEV?

A

Rodent

123
Q

Which strain of VEEV is more virulent?

A

Epizootic/Epidemic

124
Q

Dead end host for enzootic VEEV?

A

Horse, Humans

125
Q

Dead end host for epizootic VEEV?

A

Humans

126
Q

Vaccines are available for horses for what EEV?

A

East, West (yearly), VEEV (tissue vaccine)

127
Q

Vaccines are available for humans for what EEV?

A

VEEV- only military/lab workers

128
Q

EEEV enzootic vector?

A

Culiseta melanura

129
Q

WEEV enzootic vector?

A

Culex

130
Q

WEEV epizootic vector?

A

Aedes

131
Q

VEEV vector?

A

Culex

132
Q

Bovine Viral Diarrhea Virus?

A

Pestivirus (flaviviridae)

133
Q

Mucosal disease is in which BVD?

A

Cytopathogenic

134
Q

Difference between cytopathogenic and noncytopathogenic BVD?

A

Cleavage of NS2-3 (cleaved in cyto)

135
Q

Which type of BVD is more common?

A

Type 1

136
Q

Do both types of BVD have ncp and cp?

A

Yes

137
Q

How is BVD spread to calves?

A

TP

138
Q

Infection of the fetus with BVD at 1 month results in what?

A

Embryo death

139
Q

Infection of the fetus with BVD at 2-4 months results in what?

A

Persistent Infection Calf

140
Q

Infection of fetus with BVD after 5 months results in what?

A

Abortion
Deformities
Normal calf
(depends on age)

141
Q

Can non-pregnant cows spread BVD?

A

Yes! (secretions)

142
Q

Pestivirus in swine?

A

Hog Cholera/Classical Swine Fever

143
Q

Different clinical signs in African/Classical Swine Fever

A

Present the same

144
Q

What Pestivirus is reportable?

A

Classical Swine Fever (List A)

145
Q

Where is Classical Swine Fever?

A

SA, Asia, Japan, Korea

146
Q

How is Classical Swine Fever transmitted?

A

All ways!

147
Q

Pathognomonic symptoms for Classical Swine Fever?

A

Turkey Egg Kidney

Button Ulcer Colon

148
Q

Diva Vaccine?

A

Classical Swine Fever

149
Q

Vector of Louping Ill?

A

Ixodes

150
Q

Where is Louping Ill?

A

Europe

151
Q

Cup shaped depressions?

A

Calici

152
Q

How is FCV spread?

A

Carriers, Recovered, Infected cats all can spread!

-Oronasal secretions

153
Q

What organs does FCV most often affect?

A

Oral Cavity

Respiratory Tract

154
Q

FCV affecting the joints?

A

Limping Syndrome

155
Q

Calicivirus that looks like foot and mouth disease?

A

Vesicular Exanthema of Swine

156
Q

Virus infecting sea lions in CA?

A

Vesicular Exanthema of Swine (calici)

157
Q

Etiology of Infectious Bursal Disease?

A

Avibirnavirus

158
Q

Gumboro Disease

A

Avibirnavirus

159
Q

Which serotype of Avibirnavirus in symptomatic?

A

Serotype 1

160
Q

Transmission of Avibirnavirus?

A

Fecal Oral

Virology (3 decks)

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