Structures & Hemo—

Question 1

Primary Structure

Answer 1

Sequence of Amino Acids - held together by peptide bonds
The Backbone of proteins

Question 2

Secondary Structure

Answer 2

Coiled α-helix, β-pleated sheet, or a Triple-helix formed by Hydrogen bonding between peptide bonds along the chain

Question 3

Tertiary Structure

Answer 3

Folding of the protein into a compact, 3-dimensional shape stabilized by interactions between side R groups of amino acids

Question 4

Quaternary Structure

Answer 4

Combination of 2 or more protein subunits to form a larger, biologically active protein

Question 5

Conjugated Proteins

Answer 5

Composed of a protein unit & nonprotein molecule—
Myoglobin & Hemoglobin

Question 6

Heme—

Answer 6

Blood; A complex organic compound contains the Fe2+ (Ferrous ions)

Question 7

Sickle Cell Hemoglobin

Answer 7

Disease where a single amino acid of both beta subunits is changed from the glutamic acid to valine

Question 8

Sickle Cell Hemoglobin (Mutated Shape)

Answer 8

Elongated & Crescent (Sickle; More Fragile)

Question 9

Sickle Cell Hemoglobin (Mutated results)

Answer 9

Rupture Capillaries = Pain & inflamed, leading to organ damage and eventually a painfully death