Structure and mechanism of the kidney Flashcards

1
Q

What do kidneys do?

A

Filter blood to produce urine

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2
Q

What do kidneys look like?

A

They are paired organs and roughly size of a clenched fist

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3
Q

Which organisms are kidneys found in?

A

Vertebrates and some invertebrates

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4
Q

Where are kidneys found in humans?

A

Against the backdrop of of abdominal cavity just above the waist and surrounded by a layer of protective fat

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5
Q

How is body fluid composition be adjusted?

A

by what the kidney keeps as it adjusts urine composition

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6
Q

What are homeostatic functions of the kidney?

A

Electrolyte balance, blood pressure and acid base balance

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7
Q

What role do the kidneys play in electrolyte balance?

A

Salt levels are adjusted and excess is excreted

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8
Q

What role do the kidneys play in blood pressure?

A

Can adjust the volume of water in the blood

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9
Q

What role does the kidneys play in play in acid base balance?

A

If body is more acidic, the kidneys excrete more acid

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10
Q

What is the ureter?

A

Tube carrying urine away from each kidney to the urinary bladder

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11
Q

What is the urinary bladder?

A

Urine reservoir

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12
Q

What is the urethra?

A

Tube leading from urinary bladder to the outside and urine is removed by urination

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13
Q

Where are the adrenal glands found?

A

On top of the kidney

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14
Q

What are the structures in the kidney?

A

Protective capsule, renal artery and vein, central cavity, cortex and medulla

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15
Q

Wha is the protective capsule?

A

It is tough and fibrous and surrounds the kidney

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16
Q

What is the cortex?

A

An outer layer containing renal capsules and convoluted tubules

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17
Q

What is the medulla?

A

Inner layer containing loop of Henle and collecting ducts, divided into triangular pyramids

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18
Q

What is the central cavity?

A

Contains the pelvis and is continuous with the ureter

19
Q

What is the unit of the kidney?

20
Q

What is the structure of a nephron?

A

Wide afferent arteriole into glomerulus, which is surrounded y the renal capsule into the proximal convoluted tue in the loop of Henle, and out the distal convoluted tubule

21
Q

Where is the loop of Henle found?

A

In a nephron

22
Q

What is the structure of a loop of Henle?

A

A descending limb from the proximal convoluted tubule then into the descending limb

23
Q

What does the cortex contain?

A

Renal corpuscules

24
Q

What do renal corpuscules look like?

25
What is the structure of renal corpuscules?
An outer envelope of simple squamous epithelium (bowman’s capsule) surrounding a fluid filled space (bowman’s space) within which suspended is a glomerulus
26
What does most of thee cortex consist of?
Convoluted tubules
27
How do distil convoluted tubules appear?
More open
28
How do proximal convoluted tubules appear?
Not open
29
What does the medulla consist of?
Only tubules
30
What does the basement membrane contain?
Collagen mesh block molecules
31
32
What does the basement membrane filter out?
Anything larger than a plasma protein and heparin sulfate
33
What is heparin sulfate?
A negatively charged molecule that repels negative molecules
34
What is the difference between filtration and ultrafiltration?
Filtration at a molecular level
35
Where does selective reabsorption occur?
In the proximal convoluted tubule
36
What molecules are reabsorbed?
Sodium, amino acids and glucose
37
What does recovery produce?
Filtrate than is isotonic to the blood
38
What are recovery methods?
Active transport, pinocytosis, osmosis and urea
39
What does active transport recover?
Glucose, amino acids and minerals
40
What does pinocytosis recover?
Small proteins
41
What does osmosis recover?
Water follows passively
42
How do molecules move int the blood?
Through cuboidal epithelial cell from filtrate into basal channels then into blood
43
How is glucose reabsorbed by co-transporter proteins?
1. Na+/K+ pumps remove Na+ from PCT cell and low internal Na+ sets up conc. gradient 2. Entry of Na+ ions in symporter used to move glucose into PCT cell 3. Glucose out of PCT cell by facilitated diffusion 4. Moves into blood down conc. gradient