structure and function of the male reproductive system Flashcards
what is the most abundant hormone (androgens) produced in the testes?
testosterone
where is the testes located?
scrotum, descends through the inguinal canal to reach the scrotum during 8th month of development
function of the testes?
produce male gametes, sperm
spermatic cord?
contains blood vessels and nerves and supplies the testes
what is the name of the capsule surrounding each testis?
tunica albuginea
functionally testis consists of 2 compartments what are these?
seminiferous tubules and intertubular tissue, which forms the interstitium
seminiferous tubules comprise 95% of testicular vol and are lined by layers of what?
germ cells and supporting cells - sertoli cells
- all in various stages of development
e.g. spermatogonia, spermatocytes, spermatids and sperm.
sertoli cell function
- provide nutrional and mechanical support to spermatogenic cells
- also secrete inhibin which provides negative feedback on FSH secretion from the pituitary.
what is spermatogenesis
process by which male spermatogonia develop into mature sperm. it occurs in the seminiferous tubules
each ST continues near mediastinum into a straight tubule called?
the tubulus rectus
tubulus rectus leads to which structure?
rete testis (a labyrinth of cavities in the mediastinum)
rete testis connects with what structure?
epididymis
what are the components of the interstium?
loose connective tissue, blood and lymphatic vessels and other cells: leydig cells, fibroblasts, macrophages, leucocytes
leydig cells often found adjacent to blood vessels and seminiferous tubules. they are the main source of what male hormone?
testosterone
maintenance of testicular temp is essential for what?
for spermatogenesis to occur efficiently
what structures enable thermoregulation?
thin scrotal skin with sweat glands and fat
smooth muscles and skeletal muscles allowing movement of scrotum
vasculature
cremaster skeletal muscle
pampniform plexus - allows for counter-current heat exchange mechanism.
epididymis function?
coiled segment of the spermatic ducts that serves to store, mature and transport sperm between the testis and deferens.
3 parts to epididymis?
caput - head
corpus - body
cauda - tail
no of efferent tubules from the testis enter the head of the epididymis and join to form the ?
epididymal duct
how long does it take for sperm to pass through epididymis
2 weeks
sperm leaving the testis is still?
immotile and immature
vas deferens structure
- connects epididymis to the urethra
- has pseudostratified columnar epithelium, sterocilia
- musculature makes it palpable in the spermatic cord
vas deferens function?
during ejaculation, the smooth muscle of the deferent duct contracts, propels sperm and fluids forward and transferring them into the urethra
urethra function
extends from bladder to tip of the penis and constitutes a path for semen and urine.
at ejaculation, secretions come from which structures?
prostate
vesicular
bulbourethral glands
seminal vesicle location?
lobe type paired glands located next to deferent duct
seminal vesicle function?
provides secretion containing proteins, enzymes, fructose, mucus, vit C etc to nourish and stabilize the sperm
major component of coagulum is?
semenogelin I, protein expressed exclusively in seminal vesicles (area of research)
prostate gland location?
muscular single band surrounding 1st inch of urethra as it emerges from the bladder
prostate gland function?
produces, stores and secretes a clear, slightly acidic (6.6) fluid
1/3 of semen vol
prostatic function is regulates by what hormone?
testosterone
- common for this structure to inc in size w ageing
bulbourethral glands (cowpers glands) located where?
distally to prostate
cowpers glands function?
enter secretion into spongy urethra and serves as a lubricant during sexual intercourse
alkalinity of the seminal fluid helps neutralize what?
acidic environment of vagina
penis consists of 3 portions?
root
body
glans
penis is made up of what 3 erectile components?
2 corpus cavernosum
1 corpus spongiosus
ejaculatory response is under control of what nervous system?
sympathetic nervous system
erection is under control of what nervous system?
tactile stimulation - from emotional or visual stimuli - stimulating descending parasympathetic pathways from the brain
name the 3 accessory glands?
seminal vesicles
prostate
bulbourethral (cowper) and periurethral glands (littre)
fructose in seminal fluid provides what?
major energy source for sperm
prostaglandins in seminal fluid does what?
stimulate activity in the female reproductive tract
fibrinogen in seminal fluid does what?
semen coagulation after ejaculation
regulation of spermatogenesis?
- HPT axis
- receptor expression