structure and function of lower urinary tract Flashcards

1
Q

What is located anteriorly to the bladder in males?

A

pubic symphysis

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2
Q

What is located posteriorly to the bladder in males?

A

rectovesical pouch and rectum

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3
Q

What is located inferiorly to the bladder in males?

A

obturator internus muscle, levator ani muscle, prostate

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4
Q

What is located superiorly to the bladder in males?

A

peritoneum

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5
Q

What is located laterally to the bladder in males?

A

ischioanal fossa

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6
Q

What is located anteriorly to the bladder in females?

A

pubic symphysis

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7
Q

What is located posteriorly to the bladder in females?

A

vesicouterine pouch, uterus, cervix, vagina

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8
Q

What is located inferiorly to the bladder in females?

A

urogenital diaphragm, pelvic fascia, perineal membrane

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9
Q

What is located superiorly to the bladder in females?

A

uterus, peritoneum

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10
Q

What is located laterally to the bladder in females?

A

ischioanal fossa

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11
Q

What type of organ is the bladder?

A

Hollow muscular organ within the pelvis

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12
Q

What is the dome/apex of the bladder?

A

Located superiorly, pointing towards the pubic symphysis

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13
Q

What connects the bladder to the umbilicus?

A

median umbilical ligament

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14
Q

What is the body of the bladder?

A

Located between the apex and the fundus

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15
Q

What is the base of the bladder?

A

Located posteriorly, triangular-shaped

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16
Q

What forms the neck of the bladder?

A

Convergence of the fundus and the two inferolateral surfaces

17
Q

What type of epithelium lines the bladder?

A

Stratified, transitional epithelium (Urothelium/Uroepithelium)

18
Q

What is the function of the detrusor muscle?

A

Facilitates bladder contraction during micturition

19
Q

What is the stroma of the bladder composed of?

A

Collagen and elastin

20
Q

What is the normal function of the bladder?

A

Reservoir for urine storage

21
Q

What is the bladder’s barrier function?

A

Resists water passage but not truly waterproof

22
Q

What happens to bladder pressure during filling?

A

Remains constant despite increase in volume

23
Q

What initiates micturition?

A

Fullness at approximately 250ml

24
Q

What is the role of cholinergic neurotransmission in the bladder?

A

Excitatory neurotransmission for detrusor contraction

25
Q

What does urge incontinence refer to?

A

Involuntary loss of urine associated with strong desire to void

26
Q

What is stress incontinence?

A

Involuntary loss of urine when intra-abdominal pressure rises without detrusor contraction

27
Q

What does the International Prostate Symptom Score (IPSS) assess?

A

Frequency, nocturia, weak urinary stream, hesitancy, intermittency, incomplete bladder emptying, urgency

28
Q

What is a common symptom of bladder outlet obstruction?

A

Decreased force of micturition

29
Q

What is nocturia?

A

Nocturnal frequency of urination, normal <2x night

30
Q

What is the normal voiding pattern for urine?

A

300-400mls per void, 4-5 times per day

31
Q

What are storage symptoms of bladder dysfunction?

A

Frequency, urgency, nocturia, incontinence

32
Q

What is the role of bladder filling sensors?

A

Detect increase in wall tension and relay data to the brainstem

33
Q

What is the effect of aging on renal concentrating ability?

A

Decreases with age, leading to increased urine production at night

34
Q

What is the role of nitric oxide in bladder function?

A

Relaxation of bladder neck and external urethral sphincter

35
Q

What does urodynamic assessment measure?

A

Pressure from bladder and rectum during filling and voiding

36
Q

What is the management for an over-active bladder?

A

Lifestyle changes, anti-muscarinics, Botox