Structure and Function Flashcards
What are the Biochemical Roles the Liver plays?
Metabolism
Digestion
Detoxification
Clearance of Substances
Men Don’t Dare Clean
What does the liver have a Central Role in?
Protein Metabolism
Carbohydrate Metabolism
Lipid Metabolism
Synthesizing Bile Acids
Vitamin Absorption
Pirates Carve Lemons So Violently
What secondary Endocrine functions does the Liver perform?
Thyroid Hormone
Cortisol
Vitamin D
What does the Dual Blood Supply of the Liver contain?
Portal Vein: Nutrient Enriched Blood
Hepatic Artery: Oxygen Enriched Blood
From smallest to largest, list the order of Biliary Drainage
Canaliculi
Ductlets
Intrahepatic Bile Ducts
Left & Right Hepatic Ducts
Common Hepatic Duct
Common Bile Duct
Ampulla of Vater
What is the functional unit of the Liver and what does it contain?
Acinus
Portal Vein
Hepatic Artery
Bile Duct
What contains Lysosomes that break down Phagocytized Bacteria?
Kupffer Cells
Main site for clearance of antigen-antibody complexes from the blood
What is the role of Stellate Cells?
Store Vitamin A/Create Nitric Oxide
Transform to Collagen
What is the role of Oval Cells and where do we find them?
Found within Periportal Bile Ductules
Regenerate Bile ducts and Hepatocytes
What is Zone 1 of the Acinus responsible for?
Providing a base for Hepatic Regeneration
Protect Liver
What are the Biochemical FUNCTIONS of the liver?
Excretory
Synthetic
Metabolic
Organic anions of both Endogenous and Exogenous origin are…
Extracted from Sinusoidal Blood
Biotransformed
Excreted via Bile or Urine
What are Bilirubin and Bile Acids used for?
Measurement of Plasma Concentrations
What is extracted and transformed in the Liver and excreted in Bile and Urine?
Bilirubin
What does the Liver Synthesize?
Proteins
Glucose
Glycogen
Triglycerides
Fatty Acids
Cholesterol
Bile Acids
