Structure Flashcards
Glucose
Dextrose, blood sugar, grape sugar, physiologic sugar
Enzymatic hydrolysis of starch
Sweetening agaent
Glucose & Galactose
Aldohexose
Liquid glucose
Thick incomplete hydolysis of stach
Calcium gluconate
Electrolyte replenisher
Calcium gluceptate and levulate
Ca sources form 7C and 5C glucose derivative
Ferrous gluconate
Hematinic, iron deficiency anemia
Fructose
Levulose, fruit sugar
Fruits and honey , hydrolysis of inulin
Fructose
Ketohexose
Nature - furanose
Isolated crystalline - pyranose
Fructose
Isomerization of glucose by Streptomyces thru enzyme glucose isomerase
Diabetic, infant feeding formula, IV
Sweetest mono
Galactose
C4 epimer of glucose
Milk, neuronal fibers
Convertible to glucose
Xylose
Wood sugar
Boiles corn cobs, heart of decidous trees, dilute acids to xydralyze its polymer xylan
Diagnostic aid with intestinal malabsorption (Crohn’s disease, celiac disease)
Xylose
Aldopentose
Maltose, maltotriose
Alpha 1, 4
Sucrose
Alpha 1 beta 2
Trehalose
Alpha 1,1
Lactose ; cellulose
Beta 1,4
Starch, glycogen
Alpha 1,4 1,6
Inulin
Beta 2,1
Dextrose
Alpha 1,6
Maltrose
Diastatic fermentation of barley
Sweetener, tonicity adjuster, compt of beers
Sucrose
Table sugar, saccharum
Negative Benedicts, Fehlings, Barfoed, Tollens (2>1)
Hydrolysis > glu + fru called invert sugar
Barley
Hordeum vulgare
Sugar beet
Beta vulgaris
Limp silvers- cossettes
Sugarcane
Saccharum officinale
Sugar maple
Acer saccharum
Sucrose
A-D glucose + B L glucose
Sugarcane / sugar beet
Boiled with lime, ivert sugar and coagulate albumin, decolorize with SO2
Molasses
Sugar that cannot crystallize again
Sucrose
Demulcent, coating agent, sweetening agent, syrups, preservative, anti-oxidant
Trehalose
Brown seaweed in fungi
Glu + glu
Nonreducing
Lactose
Glu + gal
Milk of cow
Crystallization of whey, byproduct of cheese
Tablet diluent
Lactose intolerence
Lacks lactase/ B glycosidase
Diarrhea, GI disturbance
Butter
Fat globules by churning
Buttermilk
Liquid after globules unite
Skimmed milk
Milk without cream/ globules
Coagulum
Skimmed with renin/ rennet -»» cheese
Whey
Skimmed without coagulated proteins
Condensed milk
Partially evaporated milk
Malted milk
Milk evaporated with malt
Kymyss
Alcohol beverage with mare’s milk
Nomad in Asia
Lactulose
Alkaline rearrangement of tautomerization of lactose
Semi-synthetic
Laxative
Lactulose
Poorly absorbed, colon > lactic acid and acetic acid
GI irritants, high peristalsis
Lactulose
Encephalophaty
Flapping tremor
NH4+
Maltotriose
3 glucose
Dextrins
Partial hydrolysis of starch ( amylase, glucosidase)
Alpha glucosidase inhibitor
X intestinal absorption of sugars
Oral hypoglycemic agent
Gentianose
Glu + glu + fru
Giantiana spp
Raffinose
Glu + gal + fru
Many seeds, cottonseed
Stachyose
Gal+ gal+ glu + fru
Stachys japonica
Oxidation
Rise to sugar acids
Reduction
Sugar alcohols
Cherry juice
Ripe juice of cherry ( Prunus cerasus)
Malic acid
Mask taste of sour drugs
Pectin, incompatible with alcohol, + 0.1% benzoic acid
Plant acids
Organic 2-6C, 2-3 carboxyl groups
Accidulants effervesence, buffer systems
Citric acid 6
Scheele lemon juice
Isocitric acid - isomer
Aconitic acid - dehydrated form
Tartaric acid 4
By product of wine
Malic acid
Apple
Lactic acid 3
Infant feeding formula
Oxalic acid 2
Kamias (Averrhoa bilimbi)
Balimbing (Averrhoa carambola)
Gabi (Colocasia esculenta)
Oxidation product of ehylene glycol poisoning
Fromic acid 1
Ant bites
Volatile poison
Oxidation product of methanol poisoning
Protocatechuic acid
Onion resistant to acctacks of fungus
Shikimic
Precursor of aromatic compouns/ AA
Ascorbic acid
Cofactor of collagen hydroxylases
Scurvy
IV
Alcohol
Yeaat wine production Chemical hydration of ethylene (disinfectant/ antiseptic) USP 94.9% 15.56 Low conc - stimulant High conc- drepressant
Brandy
Wine
Whiskey
Malted grain
Rum
Molasses
Mannitol
Manna ( Fraxinus ornus)
Produce by hydrogenated fructose
Osmotic diuretic IV, laxative oral
Kidney failure, glucoma, intracranial pressure
Sorbitol
Glucitol
Mountain ash (Sorbus acuparia), now bacteria biotechnology
Sweetener (1/2 sweet as sucrose)
Not absorbed on oral - toothpaste, gum
Sorbitol
By producto of glucose metabolism when hyperglycemic (via polyol pathway)
Glucose to sorbitol
Aldose reductase
Sorbitol to fructose
Sorbitol dehydrogenase
Storage
Starch - plants
Glycogen - animals
Structure
Chitin, cellulose
Starch
From corn (zea mays), wheat ( triticum aestivum), potatum ( saolanum tuberosum) Differenciated by microscopic analysis
Amylose
Linear Beta- amylose Alpha 1,4 More soluble in water Deep blue 25%
Amylopectin
Branched Alpha 1,6 alpha 1,6 Less soluble (paste) Blu violet / purple 75%
Amylase
Enzyme breaks doem starch
Alpha amylose
Enzyme pancreatic juice (amylopsin), saliva (ptyalin)
Endproduct : glu, mal, amylopectin
Beta amylase
Endproduct nearly pure maltose
Remove maltose from non-reducing end of poly
At branching - maltose & dextrins ( incomplete hydrolysis)
Amyloplast
Storage center of starch
Starch
Tablet binder, filler, disintegrant
Antidote for iodine poisoning
Pregalatinezed starches
Chemically, mechanically processed to rupture the granules
Tablet binder
Sodium starch glycollate
Disintegrant
Hetastarch
Plasma expander 6%
Glycogen
Homoploy saccharide like amylopectin
Animal starch
More branced than starch
I test : wine red
Inulin
Fructosan linked with glucose at terminal
Asteraceae ( dandelion - Taraxacum officinale)
Evaluation of renal function ( accurate but not used)
Pheins in grasses
Phleun pratens
Agropyrene in couch grass
Agopyron repens
Sinistrin in squill
Urginea maritina
Dextran
From Leuconocstoc mesenteroides (dextran sucrase/ transglycosidase) conversionof sucrose to dextran
Plasma expander at 10%
Iron dextran
IV iron supplement
Cellulose
Not digested by mammals - lack cellulase x break beta gbonds
Ba teria, rumen microflora, herbivores
Cell wall (rigid)
Most abundant organic compound
Cellulose : plant
Chitin : fungi
Cellulose : Cotton
From purified cotton (Gossypium hiratum)
Cylindrical - young; flat, twisted - mature
Waxy cuticle - nonabsorbant
Bleached cotton yarn, absorbent cotton wool - wetted by water
Celloboise - 2 glu units
Cotton
Ammoniacal CuO
Raw cotton - dissolves leaves cuticle
Absorbent cotton - iniform swelling
Cellulose : Regenerated fibers
Isolated, controlled, modified suitable finre form
Viscose
Rayon
Surgical dressing
Continuos folament rayon
Blouse fabrics
Staple rayon
Fixed length
surgical dressing
Cellulose ethers
Methyl cellulose
Carmellose
Ethylcellulose
Cellulose acetate phthalate
Methylcellulose
Methyl chloride on alkali cellulose
Best grade 2/3 OH methylated
Lotions, suspentions, pastes
Laxative
Carmellose
Monochloroacetic acid alkali celulose
Similar with methylcellulose
Ethyl cellulose
Tablet binder
Film coat
Cellulose acetate phthalate
Eneteric coating on tablets
Pyroxylin
Soluble guncotton
Colloidon: pyroxylin + alcohol + ether (1:3)
Pyroxylin/ soluble guncotton
Topical protectant
Nitric and sulfuric acid in cotton
Colloidon
Colloidon + castor oil (3%) - Flexible Colloidon
+ camphor - Waterproof colloidon
Topical protectant
Oxidized cellulose
Treated with nitogen dioxide until carboxyl grps is 16-22%
Glucoronic acid residues
Alginate fibers
Pumped thru spinneret and immersed in CaCl2
Mannuronic acid gives weaker gel and less fiber strength
Cotton : allied drugs
Jute (Cochorus capsularis)
Flax ( Linum usitassimum)
Hemp ( Cannabis sativa)
Gums & Muscillages
Yields uronic acid + pentoses (Glu, gal, man, xy, arab) upon hydrolysis
Classified as anionic and non-ionic
Gum- Pathologic, dissolves in water
Mucilage - physiologic, slimmy masses in water
Plant exudates
Acacia (Acia senegal)
Tragacanth (Astragalus gummifer)
Ghatti gum (Anogeissus latifolia)
Steculia/ Karaya
Acacia
Arabin - Ca, Mg, K slats and arabic acid
Tapped in trees 6 y.o
Tragacanth
Bassorin (60-70%)- swelling component Tragacanthin (~30%) - water soluble Hogtragacanth - texttile and pickle 36% swells in wter, resistant to acid hydrolysis Low pH
Ghatti gum
Acacia substitute
Karaya
D- galac D- gluco Medium - pink; low - very dark Discontinuos type of muscilage Laxa, emulsifier, dental adhesive Good quality is colorless and translucent
Marine sources
Agar/ Japanese Isinglas (Gelidium cartilagineum) Algin (Macrocystis pyrifera) Carageenan (Chondrus crispus) Danish Agar (Furcellaria) Kelp (Laminaria)
Seed sources
Plantago - bulk laxative with water
Cydonium/ Quince seed
Guar gum - oral hypoglycemic, laxative
St. John’s bread- choco,galactomanan source
Microbial sources
Xanthan gum - pseudoplasctic shear thinning
Suspending agent, emulsifier, stabilizer
Other soures
Marshmallow - 10% mucilage, irritable coughs, throat, GI
Couch grass- 10% mucilage and fructan triticin
Slippery elm bark - demulcent, emmolient, nutitive property
Pectin
Middle lamela of cell walls
Abundant in fruits, roots as insoluble protopectin
Structure has D- galac with rhamnose
Protopectin
Soluble by heating with dilute acid to be soluble pectin
Pectiric acid
Insoluble degradation ofover ripe fruits
Kaopectate
Kaolin & pectin - antidiarrheal
Brand name for bismuth subalicylate
Glycosaminoglycans
Polymer mono with beta N glycosodic bonds
Peptidoglycan
Bacterial cellwall
Chondroitin sulfate
Osteoarthritis
Dermatan sulfate
Skin
Keratan sulfate
Sulfated glycosaminoglycan
Cornea, cartilage, bone
Cushion for mechanical shock
Hyaluronic acid
Anionic glycosaminoglycan
Synovial fluid
Chitin
N acetylgalactosamine
Shells of crustaceans
Heparin
Anticoagulant
Inhibits thrombin
Kordonfan variety in sudan
Best variety
White, pale yellow
Transparent
Talka gum
Acacia seya
Incompatible with alcohols 60%<
5-6% swells in water
Suspending agent, demulcent
Veriform
Wormlike
twisted coils
Tragacanth sorts
Tearlike
Ribbon/ flake gum
Longitudinal strands
Best grades contain less trag
High bassorin more viscous
Agar
Nutrient culture media Laxative Suspending agent Agarose - gel strength Agaropectin - viscosity
Alginic acid
Mannuronic and gluronic acid
Suspending agent
Food ice cream, choco
Kelp
Iodine sources
Dilates cervix
Antiobese
Atherosclerosis
Carageen
Kappa, lambda - gelling
Ioda - thickener,non gel
Danish agar
Kappa - suspending agent, gelling