Strom, Hematologic Malignancies Flashcards
1
Q
B cell markers
A
CD20
CD45
CD79a
IgG kappa or lambda
2
Q
T cell markers
A
CD3 (TcR)
CD4 or CD8
CD7
CD45
3
Q
myeloid blast markers
A
CD34 (hematopoietic stem cells)
CD33 (granulocytes)
4
Q
Acute leukemias
A
rapidly proliferating clones: BLASTS in BM and often PB
5
Q
Myeloproliferative disease
A
chronically proliferating clones which differentiate into mature cells, but they are increased in number
6
Q
Myelodysplastic syndrome (MDS)
A
clones function poorly
7
Q
Acute Myeloid Leukemia (AML)
A
rapidly proliferating clones of the myeloid, erythroid, and meg lineages
8
Q
Acute Lymphoblastic Leukemia (ALL)
A
rapidly proliferating cells of the lymphocyte lineage
9
Q
Acute Undifferentiated Leukemia
A
rapidly proliferating undifferentiated cells
10
Q
CD34+
A
blast
11
Q
CD34+, CD33+
A
myeloid blast
12
Q
CD19+, CD10+
A
lymphoid blast
