Essential Haematology Chapter 1 Flashcards
1
Q
EPO
A
90% synthesized in kidney
2
Q
TPO
A
synthesized in liver
3
Q
Fas
A
has an intracellular death domain; fas ligand on CTLs
4
Q
TNF receptor
A
has an intracellular death domain
5
Q
cytochrome c
A
binds to APAF-1 which activates caspases; from mitochondria
6
Q
caspases
A
intracellular cysteine proteases that lead to apoptosis
7
Q
BCL-2
A
anti-apoptotic protein
8
Q
BAX
A
pro-apoptotic protein