Stroke territories Flashcards
What are mimics of stroke
tumour, SDH, migraine, inflammatory
What happens if normal cerebral blood flow drops below threshold?
can get ischaemic symptoms - dysfunction if time progresses and occlusion persist then infarcted tissues
what happens at the cellular level for ischaemia
glutamate excitotoxicity
penumbral tissue
what do you see on CT for acute stroke
unenhanced cortical-wm interface loss insular ribbon sign dense MCA/dot sign loss of gm interface
how is circle of willis affected?
common to see incomplete ring
what are positive studies of endovascular stroke management
mr-clean
extend-ia
escape
what were results in mr-clean
91.4%
what is the chemical strategy for endovascular stroke
local rTPA
what is the mechanical strategy for stroke?
manipulation, retrieval, aspiration - wire, stent, penumbra - can get catheter close to thrombus possible to deliver more locally
what is the classification of intracranial
trauma, ischaemic stroke, hypertensive, amyloid angiopathy, tumour, avm, cavernoma, vasculitis, veno-occlusive disease
what is the classification of extra-axial
subarachnoid, subdural, epidural - each one of these layers give rise to comparmental space where blood can accumulate
what are liquid embolic agents
onyx
glue
phil
what trials were done in subarachnoid haemorrhage
ISAT
what pathology is there in vessel wall
CAA, vasculitis