Stroke & Syncope Flashcards

1
Q

Definition of stroke?

A

Neurologic dysfunction secondary to cerebral infarct as evidenced by neuro-imaging or signs of permanent injury

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2
Q

Definition of TIA?

A

Transient episode of neurologic dysfunction w/o evidence of infarct, initially defined as return to baseline in <24hrs

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3
Q

What is penumbra?

A

Ischemic but not infarcted tissue, potentially viable if circulation is restored promptly

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4
Q

General definition of stroke/TIA?

A

Interruption of blood supply to an area of the brain (results in deprivation of O2 and nutrients to brain cells)

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5
Q

What causes an ischemic stroke?

A

Cerebral artery blockage

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6
Q

What is a thrombotic stroke (type of ischemic stroke)?

A

Formation of clot (thrombus) w/in a cerebral artery, usually as a result of atherosclerosis

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7
Q

What is an embolic stroke (type of ischemic stroke)?

A

Clot forms away from brain and is swept through the bloodstream/lodges in narrower brain arteries

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8
Q

Common causes of embolic stroke (type of ischemic stroke)?

A

A. fib, carotid atherosclerosis, PFO (patent foramen ovale), endocarditis

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9
Q

What causes a hemorrhagic stroke?

A

Arterial leakage or rupture secondary to HTN, AVM (arteriovenous malformations), anticoagulants, or aneurysm

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10
Q

Where is the leakage located in an intracerebral hemorrhage (type of hemorrhagic stroke)?

A

Vessel w/in the brain

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11
Q

Where is the leakage located in an subarachnoid hemorrhage (type of hemorrhagic stroke)?

A

Vessel on the surface of the brain

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12
Q

What causes the leakage from an aneurysm, AVM, malignancy (types of hemorrhagic stroke)?

A

Causes other than vessels w/in the brain or surface of the brain

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13
Q

S/Sx of stroke?

A

Confusion, dysarthria, hemiparesis, unilateral weakness (extremity, face), unilateral numbness, headache, non-orthostatic dizziness, loss of coordination, ataxia, visual field defect, carotid bruit

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14
Q

How to distinguish stroke from Bell’s palsy?

A
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15
Q

Which stroke is generally associated with headaches?

A

Hemorrhagic

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16
Q

diagrams –> watch lecture

A
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17
Q

Stroke patient hx?

A

Time of onset important (<3 hrs?, if unknown use “last known well”), prior hx of stroke/any chronic deficits, recent head injury, changes in meds (including disruption of ASA/anticoag), alcoholism, seizure d/o, migraine, recent infection, DM

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18
Q

What is the cincinatti stroke scale (PE)?

A
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19
Q

What is the NIH stroke scale (PE)?

A
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20
Q

What is HINTS testing (PE)?

A
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21
Q

What is a lacunar infarct?

A
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22
Q

Does an isolated lacunar infarct involve cortical sx?

A
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23
Q

Classic lacunar infarct syndromes/sx?

A
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24
Q

What is a watershed infarct?

A
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25
Q

What does a watershed infarct mostly result from?

A
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26
Q

What can a watershed infarct present with?

A
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27
Q

Tx for Watershed infarct?

A
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28
Q

Work-up for stroke?

A
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29
Q

Treatment for ischemic stroke if definitive <4.5 hrs?

A
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30
Q

Door to needle time for ischemic stroke?

A
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31
Q

What to consider for MCA occlusion with ischemic stroke?

A
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32
Q

What to do if fibrinolysis is C/I with ischemic stroke?

A
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33
Q

tPA C/Is?

A
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34
Q

Goal when treating stroke?

A
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35
Q

Treatment for hemorrhagic stroke?

A
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36
Q

What is the BJH stroke dysphagia screen?

A
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37
Q

Discharge planning for stroke?

A
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38
Q

What is a carotid/vertebral artery dissection?

39
Q

Causes of carotid/vertebral artery dissection?

40
Q

S/Sx of carotid/vertebral artery dissection?

41
Q

Work-up for carotid/vertebral artery dissection?

42
Q

Tx for carotid/vertebral artery dissection?

43
Q

What is syncope?

44
Q

What is pre/near syncope?

45
Q

What is lightheadedness?

46
Q

50% of initial incident syncope will not have _______ ________

A

Identifiable cause

47
Q

Nature of syncope <65 y/o?

48
Q

Nature of syncope >65 y/o?

49
Q

Nature of syncope in children?

50
Q

Hx for syncope (if witness available/per pt)?

51
Q

Exam for syncope?

52
Q

DDX for syncope?

53
Q

What is neurally mediated syncope?

54
Q

Cause of neurally mediated syncope?

55
Q

How to dx neurally mediated syncope?

56
Q

What is orthostatic syncope?

57
Q

Cause of orthostatic syncope?

58
Q

How to dx orthostatic syncope?

59
Q

What is cardiovascular syncope?

60
Q

Cause of cardiovascular syncope?

61
Q

How to dx cardiovascular syncope?

62
Q

What is POTS (postural orthostatic tachycardia syndrome)?

63
Q

30% of POTS pts have syncope, with the remainder having what variety of sx?

64
Q

Cause of POTS?

65
Q

What is Hypovolemic POTS?

66
Q

What is neuropathic POTS?

67
Q

What is hyperadrenergic POTS?

68
Q

What is autoimmune POTS?

69
Q

What is mast cell degranulation POTS?

70
Q

Hx of pts with POTS?

71
Q

PE findings with POTS?

72
Q

Diagnostic criteria for POTS?

73
Q

What to use in syncope work up if hypovolemia suspected?

74
Q

Most useful tool in work-up for syncope?

75
Q

Labs for syncope workup?

76
Q

What to use in syncope work up if suspicion of cardiovascular obstructive pathology?

77
Q

What to use in syncope work up if trauma secondary to episode or ICB high on differential?

78
Q

What to use in syncope work up to r/o seizure if suspected by hx?

79
Q

What to use in work up for syncope is POTS is suspected?

80
Q

Is CXR usually done in the work up for POTS?

81
Q

Assess EKG for syncope for what?

82
Q

What is hypertrophic cardiomyopathy?

83
Q

Causes of hypertrophic cardiomyopathy?

84
Q

Average age of dx for hypertrophic cardiomyopathy?

85
Q

MC cause of sudden death in yound adults?

A

Hypertrophic cardiomyopathy

86
Q

S/Sx of hypertrophic cardiomyopathy?

87
Q

Work-up for hypertrophic cardiomyopathy?

88
Q

Tx for hypertrophic cardiomyopathy?

90
Q

Clinical decision making tools for syncope?

91
Q

Admit for syncope when?

92
Q

Tx ______ _______ if possible with syncope

93
Q

Tx for symptomatic bradycardia, Vfib, Vtach?

A

Pacemaker and/or AICD

94
Q

Management of POTS?