Stroke Flashcards
Stroke signs
Bleeding signs (unreliable: meningism/headache/coma) Ischaemia signs (carotid bruit/AF/IHD/past TIA)
Lacunar infarct signs
5 syndromes (all conscious unless thalamus involved) Ataxic hemiparesis/Dysarthria Pure motor Pure sensory Sensorimotor
Stroke acute management
Only BP down if hypertensive emergency as lowering BP may impair cerebral perfusion) Screen swallow (NBM if not good)
CT/MRI within 1hr if needs thrombolysis/likely to be haemorrhagic
Thrombolysis (alteplase) within 4.5 hrs unless (haemorrhagic/rapidly improving/bleeding risk)
Thrombectomy for large artery occlusion within 6 hrs (or 6-24 if potential to save brain tissue from MRI)
Antiplatelet (aspirin 300mg OD) once haemorrhagic excluded then longer term drug (clopidogrel) after 2 wks
Stroke prevention (1˚)
Treat hypertension/DM/hyperlipidaemia
Quit smoking
Exercise
Anti-coagulation in AF + prosthetic heart valves
Stroke prevention (2˚)
Control 1˚ RF even if not raised
Clopidogrel monotherapy post-acute stroke treatment or low dose aspirin + slow-release dihydropyridamole (thromboxane A2 inhibitor)
Stroke RFs
Hypertension
Thrombocytopaenia/Hyperviscosity
Cardiac emboli (e.g. AF/post-MI) Carotid a. stenosis
Hypo/hyperglycaemia; dyslipidaemia; hyperhomocysteinaemia
Vasculitis
Stroke post-op rehab points
Swallowing with SALT
Reduce further injury e.g. falls/pressure sores
Bladder/bowel remobilisation (without catheter)
Physio + botox for spasticity
Monitor progress e.g. time to sit up in chair
Monitor mood
Functional evaluation system in stroke rehab
Barthel’s index of ADLs
TIA signs
Specific to artery involved, generally not global signs (e.g. dizziness/syncope)
Short duration and signs resolve e.g. 1 hr
TIA causes
Atherothromboembolism
Cardioembolism
Hyperviscosity
Vasculitis
TIA treatment
Control CV RFs
Antiplatelet drugs in same way as stroke
Anticoagulation indications e.g. for cardiac emboli
Carotid endarcterectomy within 2 wks if 70% stenosis
TIA emergency referral criteria
ABCDD
Age ≥60 - 1
BP ≥140/90 - 1
Clinical features (weakness - 2/speech disturbance alone - 1)
Duration of symptoms (10-59mins - 1, ≥60 - 2)
Diabetes - 1
Subarachnoid haemorrhage signs
Thunderclap (typically occipital) headache
Vomiting
Collapse/seizures/coma
Focal neurology at presentation may show site of aneurysm
Subarachnoid haemorrhage causes
80% berry aneurysm rupture
Commonly at posterior communicating/internal carotid junction or anterior communicating/anterior cerebral junction
Subarachnoid haemorrhage tests
CT (light grey in subarachnoid space)
LP if CT -ve but history suggests SAH, >12h after headache onset CSF xanthochromic due to bilirubin