Myopathies Flashcards
1
Q
Myopathy signs
A
Gradual onset symmetrical weakness
Generally proximal weakness initially
Preserved tendon reflexes
No parasthesia/bladder problems/fasiculations
2
Q
Muscular dystrophies
A
Duchenne’s
Becker’s
Facioscapulohumeral
3
Q
Myotonic dystrophy presentation
A
DM1 more common, DM2 rarer DM1 at 20-40yrs with distal weakness Myotonia (muscle spasms) Facial weakness + muscle wasting give long haggard appearance Cataracts
4
Q
Myotonic dystrophy treatment + prognosis
A
Mexiletine may help with myotonia
Die in late middle age
5
Q
Becker’s presentation
A
Similar to Duchenne’s but milder symptoms at later age with better prognosis
6
Q
Facioscapulohumeral presentation
A
12-14yrs can’t puff out cheeks + raise arms above head
Ironed out expression
Up to 20% need wheelchair by 40yrs
7
Q
Duchenne’s presentation
A
Presents at ~4yrs with clumsy walking, standing then respiratory failure
Pseudohypertrophy seen
