Stroke

Question 1

• intracerebral hemorrhage

Answer 1

: rapidly developing clinical signs of neurological dysfunction
attributable to a focal collection of blood within the brain parenchyma or ventricular
system that is not caused by trauma.

Question 2

subarachnoid hemorrhage

Answer 2

is rapidly developing signs of neurological dysfunction
and/or headache because of bleeding into the subarachnoid space, which is not caused
by trauma.

Question 3

subarachnods stroke causes

Answer 3

Aneurysms
 Trauma
 Drugs (cocaine is most common)

Question 4

 Intracerebral hemorrhage causes

Answer 4

 Small artery disease/Hypertension
 Anticoagulants
 Trauma
 Bleeding disorders
o Ex: leukemia, things that affect clotting factors
 Tumors
 Aneurysms/AVMs

Question 5

whats more lethal

Answer 5

hemorrhages acutely–>can expand

Question 6

 Hemorrhagic stroke is preventable

Answer 6

 Prevent inappropriate anticoagulation
 Control BP and smoking
 Prevent head injuries and illicit drug use

Question 7

best way to treat hem stroke

Answer 7

Risk factor control and preventing an stroke is still the best
treatment we have

Question 8

Ischemic: Tissue plasminogen activator

 Approved

Answer 8

in ischemic stroke < 3 hours from onset

Question 9

beneft tpa

Answer 9

e: 13% absolute benefit to normal or near normal state,

doubles odds of good outcome despite risk of hemorrhage

Question 10

wndow mechancal devces

Answer 10

8 hours

Question 11

 Possible targets of neuroprotecton

Answer 11

Prevention of early ischemic injury with the excitotoxicity
 Prevention of reperfusion injury
 Prevention apoptosis and promotion of repair, regeneration

Question 12

Cerebellar hemorrhage

Answer 12

Rapid deterioration possible b/c of

compression of brainstem

Question 13

Anticoagulant-related ICH

Answer 13

Often in multiple areas
-More serious than typical
hemorrhage
-Tend to progress more than patients
not on anticoags

Question 14

Amyloid angiopathy

Answer 14

Hemorrhages b/c of fragility of
vessels
o Can also impeded blood flow
o Related to age

Question 15

Penumbra area may remain viable for several hours

Answer 15

due to the collateral arteries that supply the
penumbral zone

diffusion/perfusion mismatch