epilepsy Flashcards

1
Q

Epilepsy

A

tendency to have seizures in the absence of provocations that would cause the normal brain to have a seizure.

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2
Q

primary generalized seizure

A

a seizure that involves the entire brain at the same time. Consciousness is necessarily lost.

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3
Q

complex partial

A

a seizure of focal onset that involves areas that impair consciousness. The patient often appears dazed or confused and remembers only a part of the seizure (if at all).

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4
Q

myoclonic seizure

A

a brief generalized seizure that may be so brief as to produce a motor jerk (myoclonus) but no actual loss of consciousness.

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5
Q

petit mal seizure

A

a brief generalized seizure that interrupts consciousness but which does not result in motor symptoms (outside of, possibly, some eyelid fluttering). It may happen hundreds of times a day.

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6
Q

simple partial seizure

A

a seizure from portions of the cerebral cortex having very specific functions (i.e., motor, sensory, visual, olfactory, auditory), such that the auras are easily explained.

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7
Q

focal seizure

A

another name for a partial seizure. It arises from a specific seizure focus in the cerebral cortex. This may be a scar or an irritated area around a tumor or other cortical lesion.

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8
Q

secondary generalized

A

is the spread of a focal seizure to involve the entire brain.

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9
Q

status epilepticus

A

a medical emergency that consists of continuous or recurrent seizures over at least 30 minutes without waking up in between.

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10
Q

postictal period

A

a period of cortical depression following a seizure

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11
Q

interictal

A

the period between seizures

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12
Q

todd’s paralysis

A

a period of focal weakness after a seizure due to a prolonged postictal period in a region of cerebral cortex. This may give clues to the side and location of a seizure focus.

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13
Q

hippocampal sclerosis

A

scarring of the hippocampus. This is a common cause of temporal lobe epilepsy and occurs early in life. It is often associated with prolonged febrile convulsions in early childhood.

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14
Q

temporal lobe epilepsy

A

indicates an epilepsy with a seizure focus in the temporal lobe.

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15
Q

seizure focus

A

area of abnormal electrical excitability in the cerebral cortex.

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16
Q

prmary generalized seizures do not have

A

auras

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17
Q

geeralzied tonic-clonic seizures result in

A

autonomic upset (large pupils ,hyperthermia, tachycardia, salivation, emptying of bladder)

18
Q

petit mal & post ictal period

A

they have none

19
Q

status epilepticus

A

medical emergency-consists of continuous or recurrent seizures of 30 mins w/o waking up in between

20
Q

status epilepticus often due to

A

sedative withdrawal

21
Q

EEGs and seizure

A

2/3s of patents have abnormal activty even when not having seizure

22
Q

motor cortex seizure

A

Jacksonian (partal simple)

23
Q

complex partial are

A

limbic seizure

24
Q

later childhood–>adolescence main type of seizures

A

temporal lobe epilepsy

juvenile myoclonic epilepsy

25
Q

very young children main types of seizures

A

petit mal

metabolic defect/congenital malformations

26
Q

triggers for grand mal seizures

A

outside of CC

  • reticular formation of brainstem
  • thalamus
27
Q

clonic and post ictal phase

A

results from massive activation of inhibitory neurons in brain

28
Q

what simultaneously occurs durng colonic and post ictal phase?

A

autonomci overload

29
Q

two ways determined between grand mal and secondary generalized

A

secondary generalized has

  • aura before hand
  • repetitive movements (blinking, twtching lip smacking) beforehand
30
Q

JME is due to a

A

mutated GABA R

31
Q

petit mal seizures generally originate from

A

upper brainstem

32
Q

todd paralysis occurs if

A

motor cortex is involved

33
Q

how do secondary generalized seizures spread

A

via corpus callosum and/or reticular formation

34
Q

secondary generalized seizures can be

A

tonic
tonic-clonic
clonic

35
Q

jacksonian march

A

upper extremity–>face–>trunk–> lower limb

36
Q

foci in primary visual cortex results in

A

uniformed flashes, spots, and zig-zags of light

37
Q

foci in visual association cortex

A

hallucinations such as floating balloons, stars, polygons

38
Q

more anterior in visual association area (posterior temporal or parietal lobes)

A

more complex sensory hallucinations (people talking, etc)

39
Q

seizure near uncus of rostral medial temporal lobe

A

hallucinations of smell and taste

40
Q

why don’t cortical seizures generalize

A

collateral inhibition present in normal brain to prevent excessive excitation

41
Q

eplepsia partialis continua

A

less life threatening due to focal neuronal damage, but tendency to generalize into Major Motor Status Epilepticus, so important to terminate