Stroke Flashcards

1
Q

What is a stroke?

A

Sudden interruption in the blood supply of the brain.

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2
Q

Why does stroke cause so much damage?

A

The brain is dependent on aerobic metabolism, so any oxygen supply issue can quickly lead to irreversible damage.

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3
Q

What type of stroke is the most common?

A

Ischaemic stroke (85%).

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4
Q

What causes an ischaemic stroke?

A

Blockage in blood vessels, stopping blood flow.

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5
Q

What are the subtypes of ischaemic stroke?

A
  • Thrombotic
  • Embolic
  • Transient Ischaemic attack (TIA)
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6
Q

What are the main risks for ischaemic stroke?

A
  • Age +
  • Hypertension (HTN)
  • Smoking
  • Diabetes Mellitus (DM)
  • Atrial Fibrillation (AF)
  • Hyperlipidaemia
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7
Q

What type of stroke is rarer?

A

Haemorrhagic stroke (15%).

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8
Q

What causes a haemorrhagic stroke?

A

Blood vessel ‘bursts’, leading to reduction in blood flow.

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9
Q

What are the subtypes of haemorrhagic stroke?

A
  • Intracerebral haemorrhage
  • Subarachnoid haemorrhage
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10
Q

What are the main risks for haemorrhagic stroke?

A
  • Age +
  • Hypertension (HTN)
  • Arteriovenous Malformation (AVM)
  • Anticoagulation therapy
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11
Q

What are common symptoms of a stroke?

A
  • Motor weakness
  • Speech issues (dysphasia)
  • Swallowing problems
  • Visual field defects (homonymous hemianopia)
  • Balance problems
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12
Q

What are symptoms of cerebral hemisphere infarcts?

A
  • Contralateral hemiplegia
  • Contralateral sensory loss
  • Homonymous hemianopia
  • Dysphagia
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13
Q

What are symptoms of brainstem infarction?

A

Severe symptoms: Quadriplegia, locked-in syndrome.

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14
Q

What are lucunar infarcts?

A

Infarcts around basal ganglia, internal capsule, thalamus, and pons.

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15
Q

What results from lucunar infarcts?

A
  • Pure motor
  • Pure sensory
  • Mixed motor and sensory
  • Ataxia (loss of muscle control)
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16
Q

What does the Oxford Stroke Classification classify?

A

Stroke based on initial symptoms.

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17
Q

What are the classes in the Oxford Stroke Classification?

A
  • Unilateral hemiparesis and/or hemisensory loss of the face, arm & leg
  • Homonymous hemianopia
  • Higher cognitive dysfunction e.g. dysphasia
18
Q

What is Lateral Medullary Syndrome also known as?

A

Wallenberg’s syndrome.

19
Q

What are the symptoms of Lateral Medullary Syndrome?

A
  • Ipsilateral ataxia
  • Ipsilateral nystagmus
  • Ipsilateral dysphagia
  • Ipsilateral facial numbness
  • Ipsilateral cranial nerve palsy (Horner’s)
  • Contralateral limb sensory loss
20
Q

What are the symptoms of Weber’s syndrome?

A
  • Ipsilateral III palsy
  • Contralateral weakness
21
Q

Can symptoms help differentiate between haemorrhage and ischaemic stroke?

A

Alone, the symptoms cannot definitively tell the difference.

22
Q

What symptoms are more common in haemorrhages?

A
  • Decrease or loss of consciousness (LOC)
  • Headache
  • Nausea/Vomiting (N/V)
  • Seizure
23
Q

What does the FAST acronym stand for in stroke assessment?

A
  • Face
  • Arms
  • Speech
  • Time (999)
24
Q

What is the first step in the ROSIER Score?

A

Exclude hypoglycaemia.

25
When is stroke likely according to the ROSIER Score?
If score > 0.
26
What imaging is used to investigate stroke?
Non-contrast Head CT or MRI.
27
What is the first-line treatment for ischaemic stroke?
Aspirin 300mg + Anti-platelet therapy (Alteplase or Tenecteplase).
28
What should be maintained within normal limits in ischaemic stroke management?
* Blood glucose * Fluids * O2 stats * Temperature
29
What should be considered if systolic blood pressure is > 150 mmHg after 6 hours in ischaemic stroke?
Control blood pressure.
30
What is the second line of treatment for ischaemic stroke?
Thrombolysis.
31
What is the third line of treatment for ischaemic stroke?
Thrombectomy.
32
What should be done immediately after a TIA?
300mg Aspirin.
33
What does 'crescendo TIA' refer to?
More than 1 TIA.
34
What should be done if a TIA is suspected in the last 7 days?
Urgent assessment with a stroke specialist (<24hrs).
35
What should be done if a TIA is suspected over a week ago?
Assessment with a stroke specialist within 7 days.
36
What is the first step in managing a haemorrhagic stroke?
Neurosurgical consult.
37
What pharmacological treatment should be stopped in haemorrhagic stroke?
Anticoagulants and natithrombotics
38
What is included in non-pharmacological secondary prevention post-stroke?
* Rehabilitation and Recovery * SALT * Pain relief * Anti-seizure medications * Statin therapy
39
What is the first line pharmacological treatment for ischaemic stroke in secondary prevention?
Clopidogrel.
40
What is the second line pharmacological treatment for ischaemic stroke in secondary prevention?
Aspirin + modified-release dipyridamole.
41
What surgical procedure is used in secondary prevention for stroke?
Carotid endarterectomy.