Stroke Flashcards

1
Q

% of ischaemic vs hemorrhagic strokes

A

85% are ischaemic
- 20% caused by AF - greater mortality and morbidity

15% are haemorrhagic - higher mortality
- 2/3 intracerebral haemorrhage - most common cause HTN
1/3 subarachnoid haemorrhage
- 85% aneurysm

Risk of recurrent stroke:
- within 90 days = 5%
- within 1 year - 10%
- within 5 years - 25%
- within 10 years - 40%

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2
Q

Risk of stroke following TIA

A

At 2 days - 1.5%
At 7 days - 2%
At 30 days - 3%
At 1 year - 5% (7%)

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3
Q

When to suspect stroke

A

> 24h

1) Confusion, altered consciousness

2) Headache: gradual, increasing in ICH or sudden and severe in SAH. May have sentinel headaches in weeks prior

3) unilateral weakness/paralysis/sensory loss

4) ataxia, dysphasia, dysarthria, coordination, gait

5) Visual disturbance - homonymous hemianopia, diplopia

6) gaze paresis - horizontal and unidirectional

7) photophobia.

8) dizziness, vertigo, loss of balance

9) nausea/vomiting

10) specific CN defects - unilateral tongue weakness, Horners syndrome (mitosis, ptosis, facial anhidrosis)

11) neck or facial pain - arterial dissection

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4
Q

Posterior circulation strokes

A

Acute, persistent continuous vertigo/dizziness with nystagmus, nausea, head motion intolerance, new gait unsteadiness

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5
Q

Working out time of onset in stroke

A

If not clear, check when last known to be unaffected

If woke with symptoms this is when they were last awake and symptom free

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6
Q

FAST

A

> =1:

1) New facial weakness - asymmetry, mouth/eye drooping.

2) Arm or leg weakness.

3) Speech disturbance - slurring, dysphasia

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7
Q

Investigations if no delay to hospital

A

BM to r/o hypoglycaemia < 3.3

ECG

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8
Q

Managing suspected TIA in last 7 days

A

Symptoms resolved within 24h, typically 1h

2) 1) Apirin 300mg immediately (+PPI if dyspepsia associated with aspirin use)
- if CI d/w specialist team immediately
- if already taking low dose aspirin, continue this dose and do not give 300mg

2) Refer to be seen within 24h
- if on anticoagulant or bleeding disorder for urgent CT to exclude haemorrhage
- - will have MRI and carotid dopper

3) If > 1 TIA (crescendo TIA) - d/w specialist ?admission for observation

4) Do not use ABCD2 to assess risk of subsequent stroke or inform urgency of referral

5) Do not drive

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8
Q

Managing suspected acute stroke

A

1) Emergency admission to stroke unit

2) Inform hospital of time of onset, symptoms, current condition, meds (anticoagulants)

3) Do not start anticoagulants or anti platelet until ICH excluded

4) While awaiting transfer, monitor and give oxygen if SpO2 < 95%

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9
Q

Managing TIA > 7 days ago

A

1) Refer to specialise to be seen within 7 days

2) Do not drive until seen by specialist.

3) Safety netting advice to patient and family

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10
Q

When should you follow up TIA/stroke patients?

A

On discharge, at 6m, then annually

Also review carers of people with stroke at 6m, then annually to assess their health and social care needs

Offer verbal and written information on medications for secondary prevention - reason, how and when to take it and common adverse effects

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11
Q

Secondary prevention medications - stroke or TIA

A

1) Antiplatelet: if no paroxysmal or permanent AF
**- Clopidogrel 75mg OD
**- if clopidogrel not tolerated - aspirin 75mg OD + MR dipyridamole 200mg BD
- if clopidogrel and dipyridamole CI, use aspirin 75mg OD
- if at high risk of TIA or intracranial stenosis, secondary care may prescribe aspirin 75mg OD + clopidogrel 75mg OD for 30 days followed by mono therapy

2) Lipid modification
- atorvastatin 20-80mg OD -aim to reduce non–HDL by > 40% within 3 months
- do NOT prescribe vibrates, bile acid sequestrates, nicotinic idic and omega 3 fatty compounds to people with ischaemic stroke or TIA for secondary vascular prevention
- can only use ezetimibe in people with FHC

3) Anticoagulants: if also have paroxysmal, persistent or permanent AF or atrial flutter once IC bleeding excluded
- tretment starts immediately with TIA once haemorrhage excluded
- treatment starts within 14 days in non-disabling ischaemic stroke
- treatment starts > 14 days from onset in disabling ischaemic stroke with interim aspirin 300mg OD
-

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12
Q

Comorbidities to be managed/investigated after stroke or TIA

A

1) HTN

2) OSA - screen all patients for OSA and refer anyone suspected to have this

3) HF

4) Obesity

5) AF

6) Sickle cell disease

7) contraction - if premenopausal, do not offer COCP, offer PO methods instead

8) annual flu vaccine

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13
Q

Driving advice

A

1) 1x TIA:: do not drive for 1 month, but don’t need to notify DVLA

2) >1x TIA: notify DVLA & do not drive for 3 months, can resume if no further TIA

3) Stroke: do not need to notify DVLA initially, but do not drive for 1 month, can then Strat driving if satisfactory recovery. Notify DVLA id residual neurological deficit remains 1 month later (VF defect, cognitive, impaired limb function)

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14
Q

When should you screen for hearing problems in stroke patients?

A

Screen for hearing problems within first 6 weeks

Amsterdam Inventory Auditory of Disability (Hearing Handicap Inventory for Elderly - HHIE-S)

> 10 = >50% probability of hearng impairment -refer

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15
Q

Treating post stroke pain

A

Neuropathic - Amitriptyline, gabapentin or pregabalin

MSK - simple analgesics, TENS

16
Q

Sex advice post stroke

A

Not likely to cause further stroke

Avoid PDE-5 inhibitor for 3 months after stroke

17
Q

Spasticity following stroke

A

Localised/one limb - specialist may offer botox +/ or splinting or casting for up to 12 weeks after injections

Generalised - baclofen/tizanidine

18
Q

When is carotid endarterectomy considered?

A

CVA or TIA in carotid territory and not severely disabled

Carotid artery stenosis > 70% (Europe) , > 50^ (N.America)

19
Q

ROSIER score

A

Recognition of stroke in the emergency room

Uised in ED to predict liklihood of stroke

1) Sudden onset unilateral weakness
2) Speech distrubance without weakness
3) Visual field defect
4) Vertigo or imbalance
5) LOC or syncope
6) Bilateral pins and needles
7) Facial weakness

> =1 - stroke more likely

20
Q

Driving after multiple TIAs

A

Notify DVLA and cannot drive for 3 months
Can resume driving if no further TIAs > 3 months

21
Q

Driving after 1 TIA or stroke

A

Do not drive for 1 month
Do not need to inform DVLA if no redisual deficit

22
Q

Thromboylysis for acute ischaemic stroke

A

Alteplase within 4.5h of onset once haemorrhage excluded

23
Q

Contraindications to thrombolysis

A

1) Previous ICH
2) Seizure at onset of stroke
3) intracranial haemorrhage
4) Suspected SAH
5) Stoke or preceeding traumatic brain injury in prior 3m
6) Lumbar puncture in previous 7 days
7) GI haemorrhage in previous 3 weeks
8) Active bleeding
9) pregnancy
10) Oesophageal varices
11) uncontrolled BP > 200/120

24
Q

Thrombectomy in acute ischaemic stroke

A

Offer for patients with occulsion of proximal anterior circulation

Consider for patients with occlusion of proximal posterior circulation (basilar or posterior cerebral artery)

Can be done within 6h (with thrombolysis if within 4.5h)

Can be done up to 24h if imaging shows potential to salvage brain tissue