Stress and Disease Flashcards

1
Q

When does one experience stress?

A

when a demand exceeds their coping ability

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2
Q

Who first stated the “fight or flight” response of our body?

A

Walter B. Cannon

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3
Q

Who said that physiological stress impairs our ability to resist future stressors?

A

Hans Selye

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4
Q

What four things determine how stressed we get?

A

the nature of the stressor, the intensity, the duration, and our perception

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5
Q

What are stimuli that triggers the alarm reactions?

A

stressors

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6
Q

What is the type of stressor that just causes a general state of unpleasant arousal?

A

psychogenic stressors

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7
Q

What is the type of stressor that occurs in HIGH altitudes?

A

physiologic stressors

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8
Q

What is the nonspecific response of our body to stressors?

A

General Adaptation Syndrome (GAS)

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9
Q

What are the five stages of GAS?

A

stressor -> stress induction -> alarm -> resistance/adaptation -> exhaustion

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10
Q

What stage is the coping stage?.

A

adaptation stage = new normal homeostasis

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11
Q

What is the state of “exhaustion” in our body called?

A

ALLOSTASIS

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12
Q

What system of our body is in charge of the immediate response to stress?

A

nervous system (sympathetic nervous system)

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13
Q

What are some neurotransmitters that take part in the stress response?

A

norepinephrine, epinephrine, catecholamines

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14
Q

What is the function of catecholamines?

A

released from adrenal medulla to increase proinflammatory cytokine production

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15
Q

Which system of our body is in charge of the short-term response?

A

endocrine system

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16
Q

What steroid hormone gets increased during stress?

A

cortisol

17
Q

What are some of the functions of cortisol?

A

stimulates glucose production, anti-inflammatory (immunosuppression), induces T-cell apoptosis

18
Q

What is the sympathetic neurotransmitter and growth hormone?

A

neuropeptide Y (NPY)

19
Q

What is the hormone that initiates histamine release?

A

Peripheral corticotropin-releasing hormone (CRH)

20
Q

Which system in our body is in charge of the long-term stress response?

A

immune system (decreased T-cell cytotoxicity and B cell function)

21
Q

What two body systems affect the immune system?

A

nervous and endocrine (neuroendocrine)

22
Q

What are the four body systems that can be affected by stress?

A

cardiovascular, endocrine, immune, and gastrointestinal

23
Q

What are some cardiovascular stress-related disorders?

A

coronary artery disease, hypertension, stroke, arrhythmias

24
Q

What is the immune stress-relation disorder?

A

SECONDARY immunodeficiency

25
Q

What are some endocrine stress-related disorders?

A

diabetes type 2, and secondary amenorrhea (absence of menstruation)

26
Q

What are some gastrointestinal stress-related disorders?

A

ulcers, inflammatory bowel disease, diarrhea

27
Q

What are the two types of coping?

A

adaptive and maladaptive

28
Q

Where are catecholamines released from?

A

adrenal medulla

29
Q

What types of strategies are beneficial in coping?

A

problem-focused and social support

30
Q

What does ineffective coping lead to in healthy individuals?

A

distress or illness

31
Q

What does ineffective coping lead to in symptomatic individuals?

A

exacerbation of illness

32
Q

What stress hormones increase in the elderly?

A

catecholamines, ADH, and cortisol

33
Q

Where do excitability changes occur in the elderly?

A

limbic system and hypothalamus