Stress Flashcards

1
Q

What is the name of the syndrome that describes the stages of stress

A

General adaptation syndrome (Seyle)

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2
Q

Stages of stress

A
  1. Alarm
  2. Either resistance or exhaustion
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3
Q

What are the hormones related to stress

A

Adrenaline and glucocorticoids (eg. Cortisol)

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4
Q

What is the permissive effect

A

It is cortisol enhancing the effects of adrenaline

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5
Q

Function of cortisol

A

Increase breakdown of glycogen to glucose release
Increase fats and protein breakdown
Anti inflammatory
Immunosuppressive
Increase bone resorption, decrease bone mass
Permissive effects of adrenaline

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6
Q

Does cortisol promote or in]nhibit the release of prostaglandins and leucotrienes

A

Inhibit

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7
Q

How does anti inflammatory drugs link into stress

A

Anti inflammatory drugs like corticosteroids disrupts the normal control mechanisms, suppressing CRH and ACTH release, stress response suppressed

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8
Q

What controls cortisol release

A

HPA axis - hypothalamus-pituitary-adrenal

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9
Q

If we fail to adapt (ie exhaustion phase), what sort of risk are we putting our bodies at?

A

CVS
Immunosuppressive due to constant cortisol
Adrenal failure may result
Peptic ulcers

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