Streptococcaceae Flashcards
Staining Reaction and Shape
Gram-positive
Motility
Non-motile
capsule
Encapsulated/non-encapsulated
Catalase
Catalase negative
organisms
Homolactic acid organisms
Encapsulated Streptococcus
Streptococcus pyogenes
Habitat of Streptococcus pyogenes
Human throat
Not the normal flora of skin
transmission of Streptococcus pyogenes
via respiratory droplets
contact with cutaneous lesions
Anti-phagocytic
o With Fibronectin binding proteins
Antigenic variation
M PROTEIN
Has hyaluronic acid
Anti-phagocytic
CAPSULE
Streptococcal Pyrogenic Exotoxin
Lyosogenized strains
Responsible for Scarlet Fever
ERYTHROGENIC TOXIN (EGT)
Diagnostic test for Scarlett Fever
Intradermal injection for ANTIEGT
BLANCHING PHENOMENON
SCHULTZ-CHARLTON TEST
Susceptible: Rash
o DICK’S TEST
Oxygen labile Immunogenic (ASTO) Stab-technique Pour plate technique Agar overlay
STREPTOLYSIN O
Oxygen stable
Serum extractable
Has affinity for serum
STREPTOLYSIN S
Epidermis
Yellow crust
PYODERMA/IMPETIGO
Dermal inflammation
Thickening of the skin
ERYSIPELAS
Strep throat
Acute
Dysphagia
PHARYNGITIS
Direct extension
Hematogenous route
PNEUMONIA
NECROTIZING PASCITIS is an Inflammation and necrosis of:
o Skin
o Subcutaneous fat
o Fascia
Flesh eating disease
3 categories
o Type 2: Group A Streptococci
NECROTIZING PASCITIS
Sandpaper like rash
Starts on the trunk
“strawberry tongue”
SCARLET FEVER
Child Birth Fever
Infection after delivery
PUERPERAL FEVER
Complications
Autoimmune diseases
SEQUELAE
5 weeks
Joints
May affect the heart
Development to RHD
RHEUMATIC FEVER
After Cutaneous Infection or Strep Throat Edema of lower limbs Hypertension Dark and smokey urine
ACUTE GLORUMERONEPHRITIS
Encapsulated
BOVINE MASTITIS
Streptococcus agalactiae
habitat of Streptococcus agalactiae
Vagina and rectal area
TRANSMISSION of Streptococcus agalactiae
Vertical transmission
First 3 days after birth
High mortality rate
NEONATAL MENINGITIS
NEONATAL MENINGITIS is Associated with
o Obstetric complications o Rupture of membranes o Premature birth
remains as a significant cause of invasive disease in the newborn
GBS
Can grow in extreme conditions
Resistant to most antimicrobial agents
ENTEROCOCCI
ENTEROCOCCI VIRULENCE FACTORS
GELATINASE
SERINE
PROTEASE
CYTOLYSIN
NONENTEROCOCCI VIRULENCE FACTORS
ADHESINS
HYALURONIDASE
DNASE
Immunosupression
PREDISPOSING FACTOR
LANCET-SHAPED DIPLOCOCCI
Fastidious
Capnophilic
Streptococcus pneumoniae
Streptococcus pneumoniae: habitat
Human throat
Nasopharynx
Streptococcus pneumoniae: TRANSMISSION
Acquired endogenously
Delays ingestion by phagocytes thereby promoting multiplication of the organism in the tissues of the host.
CAPSULE
Exhibits toxicity for pulmonary endothelial cells and direct
effect on cilia that contributes to the disruption of
endothelial barrier.
Facilitates the access of pneumococci to the alveoli and
eventually their spread beyond into the bloodstream.
Lyses phagocytes and suppresses host inflammatory and
immune functions.
PNEUMOLYSIN O
Also referred to as spreading factor
It hydrolyses neuraminic acid, an important component of
mucus that covers cells of the respiratory tract and protects
them from bacterial attachment.
NEURAMIDASE
Is an autolysin that causes lytic dispersal of pneumolysin and hemolysin
AMIDASE
LOBAR PNEUMONIA
Most common bacterial pneumonia
Streptococcus pneumoniae
into the chamber of the middle ear by way of the eustachian tube and cause middle ear infection called otitis media.
OTITIS MEDIA
into the chamber of the middle ear by way of the eustachian tube and cause middle ear infection called otitis media.
SINUSITIS
Adult immunocompromised host
MENINGITIS
Alpha hemolytic
Normal flora of oral cavity
VIRDANS STREPTOCOCCI
Forms dextran from sucrose Sticky, mucoid material Dental plaque Acid production Destroys the enamel
S. MUTANS
Via dental procedure
ENDOCARDITIS