Strep pyogenes diseases and Strep agalactae. Flashcards
Name 10 disease with Strep pyogenes
tonsilitis, pharyngitits, quincy, scarlet fever, impetigo (you), erysipelas (mia), necrotising fasciitis (kaitlyn), cellulitis, purerperal fever, strep myositis.
What is the difference between tonsilitis, pharyngitis, and quinsy
tonsilitis is inflammation of the tonsils
pharyngitis inflammation of back of the throat.
Quinsy inflammation and accumulation of pus between behind the tonsils and back of the throat.
Describe symptoms of scarlett fever (caused by S.pyognes toxins)
rahs that starts on upper body face and neck that can progress the rest of your body.
Along with sore throat, vomiting, red and swollen tongue with a white film.
Describe Imepitigo (S. pyogenes)
Surface skin infection with pustules and does (have yellow crusts)- topical antibiotic creams.
Describe erysipelas S. pyogenes infection.
Skin erythema with sharp demarcated edges. Accompanied by burning and itching.
Affects the dermis- lower in skin than impetigo.
Describe cellulitis in S. pyogenes infection
red erythema and a lot of swelling and warmth (deeper than erysipelas)
Complication includes lymph drainage damage
(due to tissue damage around lymphatics which can cause lymphedema).
Describe S myositis in S. pyogenes and treatment for it.
Like cellulitis but will affect the muscle layer and can present with swelling and muscle weakness.
Requires prolonged antibiotic treatment and sometimes necrotic tissue must be cut out.
deeper than necrotising fasciitis.
What is necrotising fasciitis known as? What areas does it affect and what are complications/ treatment options.
flesh eating disease that affect limbs and gentials.
Begins as a spider bite-like skin lesion. Rash can quickly darken and blisters and gangrene can set in.
deeper than cellulitis.
bacteraemia and blood pressure complications.
antibiotics and surgery/ amputation may be required.
Who does puerperal fever affect? and where does it infect?
Affects women post partum.
Infects reproductive tract and can disseminate into bloodstream.
Symptoms associated include fever, chills, pelvic pain and foul smelling vaginal discharge.
As well as antibiotics may cause absecces that need draining.
Which strep can cause fever and blood pressure changes and breathing problems in neonates?
S. pyogene due to the presence of it in vagina an GI tract.
What is bactareamia and what are the complications and symptoms associated?
When bacterial infection has entered the bloodstream.
Causes diseemination, fever, chills rapid HR.
Can lead to drop in Blood pressure, inadequate blood flow, tissue damage and organ failure.
What are the 5 complications associated with different S pyogenes infections?
sepsis, toxic shock syndrome, acute rheumatic fever, rheumatic heart disease, acute glomerulonephritis.
PANDAS?
What does acute rheumatic fever lead to?
What are the indications?
Wht is the pathogenic mechanisms?
ARF can lead to rheumatic heart disease.
Indications include migratory arthritis.
Pathogenesis thought to be induced by M protein binding to self proteins and induction of autoimmune inflammatory responses.
What ‘bodies’ are seen within the heart in rheumatic heart disease?
aschoff boddy, make up of lymphocytes, palasma cells, macrophage and a nectrotic core.
This can impair the mitral valve (left atrioventricular valve) and heart function.
How does glomerulonephritis occur as a complication of s pyogenes?
antigen-antibody complex from strep accumulats in glomeruli and can lead to kidney damage and renal dysfuncitno.
this is normally self limiting though.
