Strep pyogenes

Question 1

In cell structure in group A Strep this blocks the binding of C3b (opsonization).80 different types

Answer 1

M protein

Question 2

Fibronectin-binding protein. adhere and invade the epithelial

Answer 2

Protein F

Question 3

Mediate attachment to host cells

Answer 3

Lipoteichoic Acid

Question 4

this virulence factor prevents opsonized phagocytosis. part of the bacterial structure;
made up of polysaccharide or polypeptide; function as antiphagocytic

Answer 4

Capsule

Question 5

Inactivates C5a (no chemotaxis)

Answer 5

C5 Peptidase

Question 6

helps destroy foreign DNA

Answer 6

DNAses

Question 7

Destroys white blood cells (WBCs),
platelets, RBCs, and other tissues; Oxygen labile

Answer 7

Streptolysin O (Hemolysin)

Question 8

Can lyse RBCs and WBCs, Oxygen stable

Answer 8

Streptolysin S (Hemolysin)

Question 9

Breakdown of connective tissue (spreading factor)

Answer 9

Hyaluronidase

Question 10

Lysis fibrin clots

Answer 10

Streptokinase

Question 11

Act as Superantigens ; responsible for most clinical manifestations of severe strep diseases,Causes a red spreading rash

Answer 11

Streptococcal pyrogenic exotoxins (SPEs)

Question 12

most common disease caused by a strep species

Answer 12

Pharyngitis

Question 13

skin infections through bites or abrasions of the skin

Answer 13

pyoderma

Question 14

skin infection usually in very young children

Answer 14

impetigo

Question 15

Skin infection with a spreading red rash with a
demarcated but irregular edge; Mostly elderly

Answer 15

Erysipelas

Question 16

Deep invasion of GAS leading to necrosis and
gangrene

Answer 16

Cellulitis

Question 17

blood infections

Answer 17

sepsis

Question 18

invasive infection characterized by a rapidly progressing inflammation and necrosis of the
skin, subcutaneous fat, and fascia; Described as “flesh-eating disease”

Answer 18

Necrotizing fasciitis

Question 19

Can occur after pharyngitis or cutaneous infection; Ag-Ab complexes, resulting in damage to the kidneys

Answer 19

Acute glomerulonephritis (AGN)

Question 20

(SPES)cause rash. carried by bacteriophage T12, rash appears on the chest then spreads to trunk and limbs lasting 5-7 days, after rash skin desquamates. (complication on pharyngitis)

Answer 20

Scarlet fever

Question 21

Occurs after pharyngitis, Inflammation of the joints, heart, blood vessels, and subcutaneous tissues; Can cause serious damage to the heart valves.

Answer 21

Rheumatic fever

Question 22

Direct Detection of Antigen

Answer 22

Group A Strep Immunoassay

Question 23

Agglutination occurs: Ag-Ab complex is visible. used to differentiate strep sp groups

Answer 23

Latex Agglutination Strep Grouping Assays