Stomach

Question 1

Gastroparesis (food passes through stomach too slow)

Answer 1

1) Underlying cause
2) Lifestyle change
3) Gastric pacemaker

Question 2

antiemitics cancer

Answer 2

Used in cancer patients:
- 5-HT3 receptor antagonists – Setrons [Ondansteron] [CTZ]
- NK1 receptor antagonists – Aprepitant

Question 3

antimemitics motion sickness

Answer 3

• Muscarinic Ach receptor antagonists – Hyoscine, scopolamine [VC]
• Histamine H1 receptor antagonists – Cyclizine, cinnarizine [VC]
  o Used in pregnancy

Question 4

antiemetics dopamine

Answer 4

– Domperidone, metoclopramide [CTZ]
- Used for drug-induced vomiting and in Parkinson’s

Question 5

coeliac disease

Answer 5

Ix: anti-TGG, also check for IgA deficiency which could give false result
1) Gluten free diet for life

Question 6

tropical sprue

Answer 6

Bloods + History
- Malabsorption from tropics and subtropics due to abnormal bacterial colonization
- Presents with diarrhoea, weight loss and macrocytic anaemia due to Vitamin B12
deficiency
1) Broad spectrum antibiotics