STIs Flashcards

1
Q

Trichomoniasis

clinical presentation

A

most often asymptomatic
if sxs present:
increase pH >4.5
vaginal irritation, malodorous, FROTHY, yellow green d/c

may see petechiae on cervix or vagina “strawberry cervix”

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2
Q

Trichomoniasis

pathogen and treatment

A

Trichomonas vaginalis - single celled protozoan parasite

Metronidazole (Flagyl) orally, single dose (or tinidazole)

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3
Q

Diagnostics for trichomoniasis

A

Nucleic Acid Amplification test (NAAT)** - faster than culture and very sensitive

Wet mount, +60% of time - may visualize motile organism

Culture - may take 7 days

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4
Q

M.C non-viral STI?

A

Trichomoniasis

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5
Q

M.C bacterial STI?

A

Chlamydia

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6
Q

Who should be screened for chlamydia?

A

Women < 25yo should be screened every yr (screen older women with risk factors) and also men with risk factors

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7
Q

Chlamydia pathogen and treatment

A

Chlamydia trachomatis - gram neg bacterium

Azithromycin (Zithromax) SINGLE dose
or Doxycycline orally for 7 days

(avoid doxycycline in pregnancy - Category D)

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8
Q

Chlamydia clinical presentation

A

most often asymptomatic
if sxs present
Women: cervical d/c, vaginal bleeding, low abd pain, fever, chills, adnexal tenderness

Men: irritated urethra, penile d/c, dysuria

can cause oral and rectal infections

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9
Q

Complication of all STIs?

A

Increases risk of acquiring & transmitting HIV

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10
Q

Gonorrhea pathogen and treatment

A

Neisseria gonorrhea - gram neg diplococci bacterium

Ceftriaxone (Rocephin) 250 mg IM
PLUS
azithromycin 1 gram PO (single dose) or doxycycline
(this regimen covers chlamydia too)

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11
Q

Complications of gonorrhea

A

HIV risk
PID and complicated pregnancy
in males epididymitis

can cause conjunctivitis, meningitis, endocarditis, and disseminated diseases

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12
Q

Clinical presentation gonorrhea

A

same as chlamydia but often more severe

can cause oral and rectal infections

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13
Q

What is Fitz-Hugh-Curtis syndrome?

A

PID complication

Perihepatitis characterized by RUQ pain & adhesions (adhesions that develop bw the liver and diaphragm)

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14
Q

Complications of PID

A
  • infertility
  • ruptured tubo-ovarian abscess - surgical emergency
  • chronic pelvic pain (esp if untreated)
  • increased risk of ectopic pregnancy
  • Fitz-Hugh Curtis syndrome
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15
Q

Clinical presentation of genital herpes

A

prodrome - burning, tingling, and/or pruritis followed by outbreak of painful versicles on erythematous base “dew drops on a red base”

can be very different however - not classical description

initial outbreak tends to be most severe

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16
Q

Tx of genital herpes

A

Acyclovir, or other “virs”

initial outbreak - tx for 7-10 days
recurrent outbreak tx 1-5 days (shorter course)

17
Q

Neonatal HSV, 3 syndromes possible ..

A
  1. localized skin, eye, mouth (SEM) dz
  2. CNS dz (encephalitis, long term morbidity, metal retardation)
  3. Disseminated dz (organ involvement, mortality common)
18
Q

Prevention of neonatal HSV considerations

A

offer women with active recurrent genital herpes suppressive viral therapy (Acyclovir) at or beyond 36 wks gestation

perform c-section delivery in women w active genital lesions or prodromal sxs

avoid intercourse/receptive oral sex w partners suspected of HSV during 3rd trimester

19
Q

Most common STI

A

HPV

Human Papillomavirus

20
Q

HPV clinical presentation

A

most asymptomatic
visible genital warts (condyloma acuminata)
precancerous/cancerous changes (anywhere infected) - persistent HPV main cause of cervical cancer (Types 16 & 18 =70%)

21
Q

Tx options for HPV warts

A
Topical Imiquimod (Aldara) 
Topical podofilox 

Provider applied options
Cryotherapy
Surgical therapy (excison, electrocautery, CO2 laser, curettage)
Trichloroacetic acid (TCA)

22
Q

HPV pregnancy considerations

A

HPV rarely transmitted to neonated during delivery

cesarean if pelvic outlet obstructed or vaginal delivery would result in excessive bleeding - what’s best for mom’s health per ACOG