Stimulus for Contraction Flashcards
impulse
a charged transmitted through certain tissue (cells) that results in the stimulation or inhibition of physiological activity
action potential
electric impulse; impulse carried by a neuron
membrane potential
measured by the electrical charge inside the cell to the charge outside the cell
resting potential
result of the unequal distribution of positively (cation- outside of cell) and negatively (anion- inside of cell) charged particles called ions
Channels
passive - always open
active - require chemical or electrical charge to open
sodium-potassium pump
actively transports sodium out across the membrane and potassium back into the cell
-removes the 3 sodium ions from cell for each 2 potassium ions it bring to the cell
polarized
resting cell
-at rest there is a net loss of positive ions from the interior of the cell, making the interior negatively charged with respect to the exterior
depolarized
inside of the cell is positive relative to the outside
when a sufficient is applied to the cell, sodium channels open and positive ions flow into cell
depolarization
reversal of membrane polarity that occurs during the production of action potential by the nerve and muscle cells
repolarization
a return to the negative charge on the inside
- restores the cells resting potential so it can depolarize again
- sodium is returned to the outside of the cell and potassium to the inside by the sodium-potassium pump, which restores the balance of ions and resting membrane potential
action potential
reverse polarity or change in electrical potential across a nerve membrane that generates an electrical current
acetylcholine
synthesized in the cytoplasm of the neuron and stored in the vesicles at the distal end of the motor neuron fibers
neurotransmitter
a chemical contained in synaptic vesicles in nerve endings that is released into the synaptic clef
synapse
the junction between 2 neurons or a neuron and its effector muscle or gland
there is no actual physical union
synaptic clef
the gap between 2 cells forming a synapse
nerve impulse or muscle impulse
electrical signal that travels along an axon
impulse passes
all directions over the surface of the muscle fiber membrane and travels through the transverse tubules deep into the fiber and reach the sarcoplasmic reticulum
sarcoplasmic reticulum
membrane network of channels and tubules of a muscle fiber, corresponding the to the endoplasmic reticulum of other cells
-contains a high concentration of calcium ions
end plate potentials
inward diffusion of sodium producing depolarization of the motor end plate
- graded in magnitude
- capable of summation
cisternae
enlarged portions of the sarcoplasmic reticulum near the actin and myosin filaments of a muscle fiber
2 events lead to muscle relaxation
- Acetylcholine is decomposed by enzyme acetlycholinesterase
- When acetylcholine breaks down, the stimulus to the muscle fiber ceases
- as result, calcium ions are actively transported back into the sarcoplasmic reticulum, decreasing the calcium ion concentration of the sarcoplasm
- linkage breaks, actin and myosin filaments slide apart, and muscle fiber relaxed
acetlycholinesterase
prevents a single nerve impulse from continuously stimulating a muscle fiber
dopamine
counteracts the effects of acetylcholine
- does not act at the neuromuscular junction; only in brain