Stimulants Flashcards
1
Q
How do CNS stimulants work?
A
alpha-adrenergic and beta-adrenergic agonists
Triggers release of DA and NE from presynaptic neurons
2
Q
What are the indications for CNS stimulants?
A
ADD, ADHD
Sleep disorders - narcolepsy
3
Q
What are the contraindications for CNS stimulants?
A
Co-administration with MAOIs
Narrow angle glaucoma
4
Q
What are the side effects of CNS stimulants
A
Minor - anxiety, insomnia, anorexia, tachycardia
Serious - drug dependence, HTN, tics (if this happens, stop treatment), cardiac arrhythmias, cardiovascular collapse (rare)
5
Q
What drugs are CNS stimulants?
A
Methyphenidate (Ritalin) Methyphenidate extended release (Concerta/Metadate, CD/Metadate ER) Dexmethylphenidate (Focalin) Dextroamphetamine (Dexedrine) Amphetamine/dextroamphetamine (Adderall) Pemoline (Cylert)
6
Q
What are the novel CNS stimulants
A
Modafinil (Provigil)
Atomoxetine (Straterra)