Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Exit Viva > stigmata > Flashcards

stigmata Flashcards

1
Q

DMS- cutaneous

A
  • heliotrope, V shaped photosensitive poikiloderma, shawl sign,
  • holster, flagellate, photodistributed erythema,calcinosis cutis
  • hands: gottrons sign/papules( over IPJ vs LE ), nailfold telangiectasia/ragged cuticle, mechanic’s hands,Raynaud’s
  • scalp poikiloderma/alopecia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

ClassX: DMS

A

bullous ,amyopathic(26%), antisynthetase S

juvenile

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

antisynthetase S features, prevalence and significance?

A

30%,
raynaud’s, mechanics hands, ILD,
anti Jo 1 ab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

juvenile DMS

A

calcinosis cutis, arthritis, RBBB, conduction)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

DMS systemic

A
  1. myositis/Esophageal/ILD/carditis;
  2. malignancy 30% ovarian worldwide, NPC locally(50% of 20%), (LN,epistaxis, cranial nerve palsy, abdo masses/ascites, breast pelvic PR exam/LOW/BH)
  3. overlap syndrome: SLe, scleroderma,MCTD, RA/Sjogrens
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

scleroderma cutaneous

A

ivory waxy lilac indurated, salt pepper dyspigmentation,
face- limited mouth opening furrows
hand- edema,CREST Calcinosis Raynauds digital infarct; nailfold capillaries Sclerodactylyl(pray)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

scleroderma systemic

A
  1. muscle motility: dysphagia, proximal myopathy,
  2. BP( renal crisis), ILD-dry cough, fine creps /pulmonary HT( exertional dysnpea, JVP)
  3. overlap
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Overlap syndromes/MCTD- kusukawa criteria

A

(SLE, DMS) raynauds, finger/hand swelling/acral sclerosis+U1 RNP, antifibrillin, antiPMScl + 1 feature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

morphea classX

A

Cx: plaque/guttate/generalised(>2 sites); bullous, linear, deep

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

post strep scleredema

A

(acute cervicofacial hardening ,mask facies, limited mouth opening/swallowing)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

scleredema monoclonal gammopathy,

A

persisitent;

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

scleredema diabeticorum

A

peau d orange erythema induration, waxy distal extremities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

papular mucinosis-stigmata , subtypes

A

clusters/linear/close spaced; flesh/waxy papules
discrete papular/acral,HIV; self healing, nodular,
+ sclerodermoid - scleromyxedema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

GVHD ClassX

A

traditional : 100d post SCT

NIH- organ specific criteria, diagnostic skin *

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

aGVHD:

A

Fx: morbilliform, follicular, petechial, acral, (st 4)TEN like 4-6w post HSCT;
staging: BSA, GIT/liver, histo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

cGVHD

A

Fx: 1)LP like: reticulate pink-violet scaly papules plaques/mucosal/nail(dorsal pterygium, anocyhia)

2) papulosquamous psoriasiform/KP follicular erythema/SCLE
3) poikiloderma 4) sclerodermoid (patchy, diffuse symmetric); EF- rippled irregular nodular , groove sign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

LSA Fx+ cX?

A
  • Atrophic ivory white wrinkled , obliterated labia majora minora introitus/meatus, cannot retract foreskin, hemorrhage, erosive; lilac margin(Extragenital)
  • irreversible scarring/stenosis; malignancy(non healing ulcers fissures nodules)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

nail LP

A

longtudinal ridging, depressions, pterygium subungual hyperkeratosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Pancreatic panniculitis-

A

ulcerated oily discharging nodule; fever abdo pain

Schmids triad- subcut nodules, polyarthritis(lytic) eosinophilia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

SPTL

A

recurrent subcutaneous lesions fever, night sweats, fatigue and weight loss,
Cx: Ulceration, haemophagocytic syndrome(pancytopenia, prolonged fever, aggressive)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

PRP CLASSx

A

Subtypes: 1)classical adult, 50%, cephalocaudal, orange red islands sparing, follicular hyperkeratosis, remit 3 y 2)atypical,icthyosiform chronic 3) classic juvenile 10% , 1 y remission

4) 25% circumscribed uncertain prognosis,
5) atypical juvenile, follicular hyperkeratosis familial CARD14, 5%
6) HIV associated( +follicular occlusion triad, lichen spinulosus like,HAART, poor prognosis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

palmar pits:

A

palmar pits:circular few mm, perpendicular edges; Approach: 1-; 2- keratoses detachment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

PPK

A

calloused palms,soles,fingertips, hypothenar,thenar eminences ;plantar fissuring, thickening weight bearing areas, palmar pits?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

PC CLASSx

A

Focal +associated :Pachyonychia congenita type 1: Jadassohn–Lewandowsky type;2- Jackson–Lawler type; new:K6a/b/c/16/17

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

EB pruriginosa

A

: prurigo like,violaceous linear scarring,trauma blistering, milia,nail dystrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

hypertrophic LP

A

(symmetric dorsal hyperkeratotic SCC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

perforating GA generalised-

A

DM, flesh-red colored grouped, central crust/umbilicated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

lichen macular amyloid MEN2a-

A

sipple ripples,AD RET thyroid medullary ca, phaechromo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

anetoderma-

A

circumscribed areas 1-2cm:flaccid, depressions, wrinkling, sac-like protrusions, skin-white blue, buttonhole sign, chest/back/neck/upper extremities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Degos-

A

porcelain white atrophic papules+central necrosis, erythema/telangiectasia, thrombotic vasculopathy:

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

EED,

A

Extensors myeloma, IgA monoclonal gammopathy , MDS, HIV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

cowden’s

A

10queing COWs in a PtEN MOOing(trichilemomma) on COBBLES(tone) on TOES(acral keratoses, pits) - hyperactive(thyroid), Breastfeeding(adenomas), diarrhea(GIpolyp) menstruating(endometrium)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

TS

A

(AD, TSC1/2, Ashleaf, CALM,shagreen(CTN),angiofibromas/collagenomas-Fibroma-gingival/subungual , EPilepsy, Low Intelligence, Angiofibroma( renal angiomyolipoma, pulm lymphangioleiomatosis, cardiac rhabdomyoma)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Muirr torre syndrome

A

(AD MLH1/MSH2 DNA mismatch repair, MSI; colon/GU/lung.breast CA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

EGFR inhibitor( cetuximab, erlotinib, gefitinib)-

A

CLR/breast/pancreatic/nonsmall cell lung; papulopustular, tetracycline-responsive ,aw xerosis, brittle hair paroncyhia, PG

36
Q

NLD

A

symmetric pretibial sclerodermatous plaque red-brown circumscribed elevated rim→yellow periphery central atrophy/telangiectasis
hypoanesthesia, alopeciaSCC

37
Q

cutaneous rosai dorfman -

A

a/w :10% skin fever, +-massive painless bilateral cervical lymphadenopathy extranodal-soft tissue, eye, salivary gland, URT, CNS, bone, immune dysfunction

38
Q

xanthoma disseminatum-

A

mucocutaneous xanthoma, DI, flexural

39
Q

EPS

A

(rosegray sinuous, neck face, flexural;elastic;penicillamine)

40
Q

eosinophilic follicultis:

A

(follicular inflammatory infiltrate-eosinophils)

41
Q

Ofuji

A

-recurrent crops papules plaques studded sterile follicular pustules, annular, central clearaing, 50% pruritus/peripheral eos;

42
Q
  1. HIV follicultis:
A

(pruritic, truncal, papular)/hematologic malignancy assoc

43
Q

alopecia mucinosa

A

(children/young adult) alopecia, prominent follicular opening, idiopathic vs lymphoma associated(older, widespread)

44
Q

men2B

A

-(blubbery lips+ thyroid medullary CA+phaechromocytoma)

45
Q

Melkersson-Rosenthal syndrome

A

recurrent swelling lips, Facial palsy (muscle weakness)tongue fissuring

46
Q

rhinoscleroma- INVX

A 
Klebsiella  rhinocslceromatosis(MacConkey agar) 
warthin starry(G-ve intra/extracellular rod)  mikulicz cells, russel bodies,
47
Q

rhinoscleroma-

A

clinical: catarrhal-atrophic(obstructive purulent rhinorrhea), granulomatous(bony destruction, LN),

48
Q

IGD-

A

arthritis, annular plaque linear cord trunk axilla medial thigh, RA

49
Q

PNGD-

A

umbilicated papule(extensor, symmetrical)RA SLE, Wegener, LCV, vasculitis, palisading granuloma

50
Q

Follicular atrophoderma- KP atrophicans spectrum

A

follicular papules, pitted atrophic depressions, vermiculate reticulate pattern, scarring alopecia scalp eyebrow/lashses

51
Q

trichodysplasia spinulosa

A

(spiny projection,polyoma virus, ,LM spicule test, immunosuppressant, antiviral)

52
Q

1Atrophoderma vermiculatum

A

-cheeks, preauricular, upperlip
aw : sporadic, AD, sporadic, rombo(milia, telangiectasia, BCC/TE; bazex, - multiple BCC, nicholas balus, tuzun(fissured tongue) CHH(blaschkoid follicular atrophoderma)

53
Q

ulerythema ophryogenes-

A

lateral1/3 eyebrows(scarring alopecia), temples cheeks

aw: Noonan, Conelia de lange

54
Q

.keratosis folliculitis spinulosa decalvans-

A

scarring alopecia -scalp eyebrow/lash+ PPK, photophobia

55
Q

LPP graham little syndrome

A

–lichenoid follicular eruption, scalp scarring alopecia, non scarring alopecia axilla public hair ;

56
Q

piezogenic pedal papules-

A

skin soft plantar medial soles wt bearing/disappear elevation, orthotics/Sx

57
Q

EDV

A

-(TV like-pigment; verrucuous-hands feet face);

58
Q

cutaneous plasmacytosis:

A

LN+HSM, FBC/ESR, total protein serum electrophoresis(hypergammaglobulinemia), urine-bence jones( MM), constitutional,

59
Q

antimalarial pigmentation

A

blue black grey

pretibial face hard palate subungual

60
Q

minocycline pigmentation

A

(scars, LL, fe granules/melanin);

61
Q

erythema dyschromicum perstans:pruritc erythema

A

->grey macules,halo?symmetric, trunk, proximal extremities, melanophages+melanin incontinence; HIV/NH4No2)

62
Q

LPP

A

:type ⅘ phototype, papules,ill-defined oval,confluent; slate-grey;diffuse, reticulate, blotchy; face neck sunexposed; basal vac+melanophages; henna/dye/fragrance)

63
Q

SAPHO

A

-synovitis, acne conglobata, pustulosis, hyperostosis(thickening/growth), osteitis

64
Q

Sneddon wilkinson’s

A

IgA paraproteinemia dapsoneR

65
Q

IgA pemphigus-

A

(subcorneal pustulosis-Ig A ab against desmocollin,intraepidermal neutrophilic-sunflower configuration)-

66
Q

SDRIFE

A
  • 1)systemic drug exposure(hours-d),2)sharply-demarcated erythema buttocks/thighs
    3) +1 flexure 4)symmetry 5)absent systemic,
67
Q

TEC

A

painful acral/intertriginous erythema-dusky-petechiael/edema/bullae+ desquamative gingivitis/gut; 2-3w postchemoRx(cytarabine, doxorubicin, 5FU, doclitaxel, MTX)

68
Q

neutrophilic eccrine hidradenitis ,

A

Periorbital- AML, perieccrine neutrophils

69
Q

Reiter’s

A

circinate balanitis,keratoderma blenorrhagica/psoriasiform rash/nail, arthritis, uveitis/iritis+ urethritis);

70
Q

angiokeratoma mibelli-

A

warty-distal limb, fordyce-scrotum/vulva blue red;

71
Q

multiple : angiokeratoma corporis diffusum

A

-symmetrical bathing trunk

Fabry’s fucosidosis

72
Q

Fabry’s -

A

XLR , a-galactosidase A deficiency,lysosomal storage, urine birrefringent maltese cross(lipid globules), +/-mucosa,hypohidrosis, HOCM, NL(pain+ paresthesia, cerebrovascular),corneal opacities prog CRF,

73
Q

fucosidosis

A

sinopulmonary, organomegaly, dysostosis multiplex)

74
Q

glomeruloid hemangioma/cherry angioma

A

Polyneiropathy, Organomegaly, Endocrinopathy M-protein, Skin changes-hyperpig/trichosis/hidrosis/scleroderma/clubbing+leukonychia aw myeloma, castleman, plasmacytoma)

75
Q

Arsenic

A

-ROS, altered DNA methylation, bowens, NMSC,↑internal malignancy(lung bladder/prostate CA(smokers), GIT/liver)

76
Q

Organ transplant NMSC Risk

A

(swedish 2013 ,accelerating x300(H/L) X200(renal) ; korea 2014 x26)

77
Q

Gorlin:

A

1) >5/early-onset(2, odontogenic keratocyst,
2) dysmorphism(frontal bossing hypertelorism);falx lamellar calcification
3) 1deg relative

macrocephaly/cleft lip palate/bifid vertebrae/polydactylyl
medulloblastoma/meningioma/ocular, ovarian fibroma

78
Q

Bazex:

A

XLD, follicular atrophoderma, milia, hypotrichosis/hidrosis

79
Q

Annular elastotic giant cell granuloma-

A

central clearing centrifugal extension, elastolysis elastophagocytosis,

80
Q

HIES

A

IgE>1000, cold abscess, purulent pneumonia,

Skeletal(coarse, broad nasal,bossing, osteopenia), lymphoma

81
Q

WAS-

A
  1. ↑IgE/IgA,↓IgM/IgG, recurrent pyogenic infx

2. bleeding ↓plr, 3. persistent eczema

82
Q

CGD-

A

abn NBT reduction, phagocyte failure+granuloma formation

83
Q

buschke ollendorffsyndrome

A

connective tissues nevi

84
Q

Goltz

A

( telangiectasia, vermiculate dermal atrophy)

85
Q

anetoderma-Primary-

A

Jadassohn(preceding inflammatory)vs Shweninger(absent)/familial

86
Q

anetoderma-Secondary

A

inflammatory dermatosis(site of previous)—

1) drug-penicillamine,
2) infection-VZV folliculitis,TB,syphilis/tumor-autoimmune(APS)/HIV;
3) DF, involuted hemangioma

Exit Viva (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions