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ddx Flashcards

1
Q

photodist poikiloderma DDX

A

DMS/SLE/MCTD
photodrug(CCB-Telangiectasia),
TMEP, poikilodermatous MF

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2
Q

photodist erythema

A

DMS/SLE( no heliotrope, sparing IP joints)/MCTD

MCTD, drug/photo/airborne contact dermatitis; photodermatoses

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3
Q

nailfold capillary telangiectasia/erythema-

A

scleroderma, DMS

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4
Q

Lichenoid papules over hands dorsum ddx

A

DMS
SLE, MRH(coral beeding),
xanthoma( yellowish hue)

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5
Q

generalised sclerosing Ddx

A

1) scleroderma/drug induced(bleomycin, taxanes, vinyl chloride, silica)
2) scleromyxedema,poststrep Scleredema
3) CGVHD, PCT,NSF(absent facial/paraproteinemia),

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6
Q

localised sclerotic Ddx - non facial , non linear

A
  1. morphea/extra genital lichen sclerosus/.cGVHD,
  2. eosinophilic fasciitis
  3. PCT
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7
Q

localised sclerotic Ddx -facial

A

morphea

morpheic BCC, MAC(perineural, mets)

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8
Q

localised sclerotic Ddx -linear

A
  1. linear morphea

2. atrophoderma of moulin(linear, blaschkoid),

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9
Q

localised sclerotic Ddx -breast chest wall

A
  1. radiation dermatitis/cutaneous metS-ca en cuirasse/DFSP

2. morphea/extra genital lichen sclerosus/cGVHD,

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10
Q

papular mucinosis-ddx

A

ddx papular GA/Sarcoid;

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11
Q

scleromyxedema ddx

A

scleredema, leprosy, granulomatous dermatitis, disseminated GA, sarcoid, Lymphoma

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12
Q

-LSA Ddx:

A

erosive LP /MMP/morphea/SA

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13
Q

papulosquamous LP

A

-guttate psoriasis/lichen planus/P rosea/2 syphilis

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14
Q

lichenoid papules -LP

A

lichen amyloidosis, papular mucinosis, lichenoid sarcoidosis/GVHD

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15
Q

Pigmentation -LP

A

Lichen planus/pigmentosa/ prurigo pigmentosa(itchy)/lichenoid eruption/Peutz Jegher( hyperpigmented macules palms sole)

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16
Q

Oral LP-

A

immunobullous, GVHD, SCC, concomitant malignancy

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17
Q

Nail LP

A

GVHD,

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18
Q

Warty verrucuous LP

A

I:hypertrophic DLE/LP/ poro; EB pruriginosa/EDV, atypical infx,eruptive KA/SCC

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19
Q

blister + LP

A

pemphigoides(coexistant BP), bullous LP( within LP lesions, intense interface)

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20
Q

PRP

A

DRESS, psoriasis, drug-induced psoriasiform , SCLE

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21
Q

Acquired PPK

A

Drug-arsenic, arsenic,bleomycin,hydroxyurea,aquagenic, ; I-PRP/Reiter, TB, leprosy ;M-bazex,tripe palms,MF/hypothyroid, nutritional

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22
Q

palmar pits:

A

D-arsenical I-pitted keratolysis I-punctata, punctate porokeratosis; M-Gorlin,,EDV,
G acropigmentation of Kitamura; Cowden ,Darier

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23
Q

scaly figurate erythema

A

I: Annular psoriasis/ LP/porokeratosis
I:SCLE/ Sjogrens/
M:EGR
G: GA

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24
Q

deep figurate erythema

A

deep EAC inflammatory morphea,tumid lupus
M: MF/pseudolymphoma
G:AEGGG, GA,

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25
Q

? Erosive figurate erythema

A
  • IgA pemphigus vs SPD

- LABD

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26
Q

repeated infx(molluscum, simplex, bacterial)+ eczema ?

A

1) immunodef-HIES,WAS, CGD

2) ?malignancy(CTCL):

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27
Q

shin/LL –

A

NLD ,pretibial myxedema
panniculitis/tumidLE/
morphea/scleroderma/scleromyxedema

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28
Q

itchy shin papules

A

1) perforating dermatoses/folliculitis/caclcinosis/GA
2) hypertrophic LP/pemphigoid nodularis(overlap)
3) EB pruriginosa

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29
Q

Perforating dermatoses:

A

inherited RPC;EPS,Kyrles(acquired)

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30
Q

upper back –

A

D:amyloidosis/scleredema/follicular mucinosis/REM/

dermatomyositis/lupus mucinosis

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31
Q

Ear-

A

ALHE, kimura disease

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32
Q

Papulosquamous/pityriasiform

A

1) SCLE, PLC/parapsoriasis/MF

2) guttate psoriasis/secondary syphilis/PR(herald patch),

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33
Q

zosteriform-linear, dermatomal:

A

HSV/VZV,bullous ADR,Zosteriform mets

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34
Q

breast-

A

erysipelas, carcinoma erysipelatoides, lymphangioma circumscriptum

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35
Q

anetoderma- Ddx-

A

1.atrophoderma ,mid dermal elastolysis,papular elastorrhexis
2.post traumatic/infectious/acne scars
3.CTN/neurofibroma/ nevus lipomatosus superficialis
G: Goltz

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36
Q

a) multiple indurated yellowbrown plaques

A

G-NLD, NXG, GA; sarcoidosis,AMYLOID

D-histiocytic(XG, xanthoma, PNH,RSD)

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37
Q

yellowish neoplasms-

A

sebacous/xanthoma/Xanthelesma/
histiocytic/amyloid,
BCC,

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38
Q

b)disseminated red brown Granulomatous:

A

granulomatous dermatitis, disseminated GA/scleromyxedema,sarcoid, lepromatous leprosy, /Lymphoma

39
Q

c)discrete Multiple brown papules trunk-

A

eruptive spitz/DF/histiod leprosy/molluscum
histiocytosis: xanthoma-papular,eruptive(yellow) disseminatum, XG, GEH; mastocytosis
sarcoid; disseminated GA

40
Q

face e)multiple brown papules -

A

histiocytic(generalised eruptive histiocytosis, cutaneous rosai dorfman(S100+,CD1a-) progressive nodular histiocytosis, XG, eruptive xanthoma ,XD)
syringomas, sarcoid

41
Q

red brown plaques

A

(AGE?old-malignancy, multiple)

inflammatory: tumid lupus, leprosy; sarcoid, histiocytes- XG, RDD mastocytoma; vasculitis granuloma faciale/EED

42
Q

f)multiple facial papules-flesh colored

A

eruptive syringoma, sebcaeous neoplasms (Muirr torre syndrom) systemic amyloidosis

angiofibromas/collagenomas- TS
brooke spiegler-TE/Cylindroma/Spiradenoma
cowden(trichilemomma)
Fibrofolliculoma

43
Q

g)grouped brown papules-

A

benign - segmental neurofibromatosis, agminated IDMN/Spitz, angiokeratoma/lichen aureus

44
Q

h)acneiform- anticonvulsant,HE, iodide/bromide,

A

anticonvulsant,HE, iodide/bromide, EGFR inhibitor( cetuximab, erlotinib, gefitinib)- CLR/breast/pancreatic/nonsmall cell lung; papulopustular, tetracycline-responsive ,aw xerosis, brittle hair paroncyhia, PG

45
Q

ddx massive LN+ brown papules:

A

cutaneous rosai dorfman Kikuchi’s, myeloproliferative, cutaneous mets

46
Q

FACE/H+N

Pustules/erosions-

A

Ofuji,ACD, PF, eczema herpeticum

47
Q

FACE/H+N

smooth Red plaque

A

( tumid lupus, sarcoidosis/Histiocytosis/lymphoma) vasculitis granuloma faciale/EED,

48
Q

FACE/H+N follicular papules/pustules

A

eosinophilic follicultis
Ofuj
HIV(pruritic, truncal, papular)/hematologic malignancy assoc

49
Q

head/neck flesh colored verrucuous plaque:

A

alopecia mucinosa idiopathic vs lymphoma associated(older, widespread)
Nevus sebaceous, epidermal nevus ,

50
Q

periorbital granulomatous-

A

(LMDF) acne agminata, granulomatous rosacea, folliculotropic T cell lymphocytosis, micronodular sarcoid , eruptive syringoma

51
Q

FACE Psoriasiform photodistributed plaque-

A

SCLE/DLE(annular, psoriasiform), facial discoid dermatosis, DLE like sarcoidosis GVHD

52
Q

FACE/H+N

A

solitary ulcer/odd site-malignancy, infection,
bullous FDE, trigeminal trophic syndrome/artefacta(?lateral medullary syndrome
impaired somatic sensation, parestheisa, traumatic-relief, faulty sympathetic innervation,
fluoxetine erosive pustular dermatosis scalp),

53
Q

granulomatous oral swelling :

labial swelling??

A

OFG/TB/Sarcoid/crohn’s/Weg/Amyloid,Ascher’s TAS COW lip swells!
granulomatous rosacea/solid facial edema,angioedema/amyloidosis/ allergy(food, DTH dental metals)multiple mucosal neuromas: men2B-

54
Q

papillomatous:oral swelling :

A

papillomatous:Verrucuous CA=oral florid papillomatosis;oral AN,

55
Q

granulomatous nasal nodule

A

(? nasal obstruction/immunodef/recalcitrant)
-infection- TB* orificialis cutis, rhinoscleroma, mucocutaneous leishmaniasis,deep fungal-rhinosporidiosis, paracoccidio,sporo;atypical mycobacteria, syphilis/leprosy *upper airway granuloma; neoplastic- nodular SCC/KA, extranodal nasal NKT cell; Inflammatory: sarcoid, wegeners, churg strauss, rosai dorfman

56
Q

Granulomatous erythematous papules(extra-facial):

A

papular GA/Sarcoid/xanthoma/RDD; infective granuloma(NTM); ALHE

57
Q

Granulomatous dermatitis-

A

IGD/drug,patch/interstitial GA,sarcoid,

58
Q

PNGD

A

papular GA perforating disorders,I: rheumatoid nodules/rheumatoid nodulosis/subcutaneous GA

59
Q

GA

follicular papules/dyskeratinization

A

Follicular atrophoderma- KP atrophicans spectrum HV, atrophia maculosa varioliformis cutis, erythromelanosis facei, KP ,trichodysplasia spinulosa

60
Q

keratosis folliculitis spinulosa decalvans

A

lichen spinulosus, lichen nitidus(like PMLE/sarcoid), lichen syphilliticum

61
Q

LPP graham little syndrome

A

KP ; Grovers Dariers, flegel’s,GVHD

62
Q

Solitary scaly plaque-

A

bowen’s, hidroacanthoma simplex, sbcc

63
Q

Warty verrucuous –

A

I:hypertrophic DLE/LP/porokeratosis
infective- EDV, HPV, mycobacterial deep fungal,
malignant: eruptive KA/SCC,
G- EB pruriginosa

64
Q

Generalised verrucosis:

A

EDV, HIV organ transplant SCID

65
Q

localised verrucuous/follicular hyperkeratosis+-blashkoid

A

Porokeratotic eccrine ostial and dermal duct nevus/
nevus comedonicus(dilated follicular ostia cornified)/
milia en plaque
epidermal nevus

66
Q

Calcinosis-dystrophic-(dermis/subcutis/absent organ)

A

iatrogenic/trauma/neoplasm-cyst,pilomatricoma, CTD, LE/CCLE, morphea, scleroderma, CREST, juvenile dermatomyosistis; metastatic(+organ involvement-hypercalcemia/phosphatemia,CRF, Albright’s hereditary osteodystrophy-shortened 4/5th MC, short stature); idiopathic- calcinosis scroti

67
Q

Hyperpigmentation drugs

A

drugs- AM; amiodarone
chemo(busulfan, cyP,hydroxyurea);
mino;metals;
endocrine

68
Q

diffuse slate gray sun exposed-

A

amiodarone,antimalarial
psychotropic-
metals Ag,Me, gold

69
Q

redbrown

A

clofazamine(drug in fat); Addisons/cushings; arsenic(guttate leukoderma)

70
Q

blue-black

A

minocycline,clofazimine(lesional); AM

71
Q

Hyperpigmentation

A

drugs- FDE
erythema dyschromicum perstans:
LPP:

72
Q

axilla/groin annular circinate vesicopustules -

A

Sneddon wilkinson’s- IgA pemphigus-herpetiform pemphigus ,
LABD, DH
pustular psoriasis,

73
Q

Raynaud’s-

A

physical- cold, vibration, drug, CTD- DMS, SLE, overlap, cryoglobulinemia, Buergers, thoracic outlet

74
Q

Posterior neck induration-

A

scleredema/nuchal fibroma

75
Q

multiple brown patches plaque

A
  • cutaneous plasmacytosis/benign pretibial lymphoplasmacytic infiltrate
76
Q

(shoulder plaque)

A

Leiomyoma/connective tissue nevus/DFSP/dermatomyofibroma

77
Q

special sites: intertriginous

A

SDRIFE-

TEC -Eccrine squamous syringometaplasia

78
Q

warty/vegetative,fisurred/erosive?: intertriginous

A

hailey hailey,PV,

inverse psoriasis, darier’s

79
Q

seborrheic distribution (V-back),

A

PF, Dariers, SCLE,

80
Q

ORAL GENITAL SYNDROMES: + OCULAR

A

erosive LP,LP syndrome-vulvovaginal gingival; immunobullous(MMP, PV); reiter’s

81
Q

Erosive genital/perineal plaque: inflammatory/malignancy

A

LSA+SCC/bowens/empd???leukoplakia

82
Q

genital growths

A

Sclerosing FB lipogranuloma

I:premalignant- HPV, Condyloma acuminata, Bowenoid papulosis N:Erythroplasia queyrat, Verrucuous carcinoma

83
Q

genital annular

A

GA, circinate balanitis Reiter’s :

84
Q

genital erosions

A

bullous/ erosion FDE, pemphigus, papular acantholytic dyskeratosis, hailey hailey, PG/Crohns
infectious-syphillitic chancre, TB, Leishmaniasis

85
Q

grouped small angiomatous vascular lesions

A

angioma,angiokeratoma

Unilateraral nevoid telangiectasia /angioma serpiginosum

86
Q

multiple/solitary larger vascular,

A

glomangioma, glomeruloid hemangioma/cherry angioma

Glomus tumor- glomuvenous malformation

87
Q

scalp red nodule

A

angiosarcoma ddx hemangioendothelioma

AFX, melanoma, BCC/SCC

88
Q

KS

A

KS:acroangiodermatits,

angiolupoid sarcoid

89
Q

Ddx- ALM,

A

talon noir-trauma, minute black dots, spindle cell nevus of reed

90
Q

multiple nevi

A

in transit melanoma mets, Eruptive DF- CTD eruptive spitz,

91
Q

multiple NMSC

A

1.chronic arsenicism/Radiation/-drug-induced-Organ transplant
2. Immunosuppressed
lymphoma/HIV, EDV-3,5,8,10,47
3.Xeroderma pigmentosum/ EDV/Naevoid BCC syndrome/ Bazex’s Rombo syndrome

92
Q

Gorlin:

A

ddx Rombo- BCC, TE, milia

93
Q

EMPD

A

Bowens, supf BCC, MIS

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