Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

DipGUM > STI Treatment > Flashcards

STI Treatment Flashcards

Treatment regimens

1
Q

Which STIs require a TOC

A 
GC
M gen
Syphilis
Chlamydia in pregnancy
Rectal chlamydia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the recommended treatment for chlamydia

A

Doxycycline 100mg bd 7 days (avoid in pregnancy)

Azithromycin 1g stat followed by 500mg od for 2 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are alternative treatments for chlamydia?

A

Erythromycin 500mg bd for 10-14 days

Ofloxacin 200 mg bd or 400mg od for 7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the recommended treatment for rectal chlamydia?

A

Doxycycline 100mg bd for 7 days

Alternative
Azithromycin 1g stat then 500mg od for 2 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the treatment for first episode NGU?

A

Doxycycline 100mg bd 7 days

Alternative :
Azithromycin 1g stat then 500mg od 2 days
or
Ofloxacin 200mg bd or 400mg od 7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the treatment for recurrent NGU?

A

If doxy first then:
Azithromycin 1g stat then 500mg od for 2 days plus metronidazole 400mg bd for 5 days

If Azithromycin first then:
Moxifloxacin 400mg od 10days plus metronidazole 400mg bd for 5 days
Alternative :
Doxycycline 100mg bd for 7 days plus metronidazole 400mg bd 5 day’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the treatment for M Gen?

A

Doxycycline 100mg bd 7 days followed by
MRAM neg - Azithromycin 3 days
MRAM pos - Moxifloxacin 400mg od 10 days

Azithromycin 3 days followed by
MRAM neg - TOC
MRAM pos - Moxifloxacin 400mg od 10 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Treatment for TV?

A

Metronidazole 2g stat
or
Metronidazole 400-500mg bd for 5-7 days

Alternative :
Tinidazole 2g stat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Treatment for non responsive TV?

A

Repeat course of 7 day metronidazole therapy

Then increase dose:
Metronidazole or Tinidazole 2g daily for 5-7 days
or
Metronidazole 800mg tds 7 days

Then
Tinidazole 1g bd or tds for 14 days plus intravaginal Tinidazole 500mg bd for 14 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Treatment for phthirus pubis?

A

Malathion 0.5% to dry hair for 2-12 hrs
Permethrin 1% cream rinse damp hair 10 mins (safe in pregnancy)
Phenthrin 0.2% dry hair 2 hours
Carbaryl 0.5% dry hair 12 hours

Eyelashes Permethrin 1% 10 mins. Keep eyes closed
or
Inert opthalmic ointment with paraffin bd 8-10 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Treatment for scabies

A

Permethrin 5% cream whole body chin down 8-12 hrs rpt after 1 week

Malathion 0.5% aq lotion whole body for 24 hrs rpt after 1 week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Treatment for crusted scabies

A

Permethrin cream od 7 days then twice weekly until cure PLUS

Ivermectin 200mcg/kg days 1,2,8,9,15

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Treatment for HCV

A

Direct-acting antiviral agents DAAs target nonstructural proteins preventing viral replication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Treatment for chronic HBV

A

Normally given to adults with DNA>2000 IU/ml or presence or absence significant necro inflammation and fibrosis

Tenofovir disoproxil fumerate TDF
Tenofovir alafenamide TAF
Entecavir
Pegylated interferon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Treatment for HBV in HIV

A

Risk of antiretroviral resistent HIV of monotherapy lamivudine, TDF, TAF, entacavir
Use as triple ART

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Treatment of HAV

A

Supportive measures
Mild/moderate manage as OP rest and hydration
Severe with vomiting dehydration and hepatic decompensation admit to hospital

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

First line treatment for GC?

A

Ceftriaxone 1g stat IM

If cipro susceptible then:
Ciprofloxacin 500mg PO stat

18
Q

Alternative treatments for GC?

A

Cefixime 400mg PO + Azithromycin 2g stat

Gentamycin 240mg IM + Azithromycin 2g stat

Spectinomycin 2g IM + Azithromycin 2g stat
(not pharyngeal GC)

Azithromycin 2g stat

19
Q

Treatment for disseminated GC?

A 
Ceftriaxone 1g IM/IV 24 hrly
Cefitaxime 1g IV 8 hrly
Ciprofloxacin 500mg IV 12 hrly
Spectinomycin 2g IM 12 hrly
7 days treatment may be switched to oral 24-48 hrs after sx improve
Cefixime 400mg BD
Ciprofloxacin 500 mg bd
Ofloxacin 400mg BD
20
Q

Treatment of GC in pregnancy

A

Ceftriaxone 1g IM
Spectinomycin 2g IM
Azithromycin 2g PO

21
Q

Treatment for chancroid

A

Azithromycin 1g

Ceftriaxone 250mg IM

Cipro 500mg bd 3 days
Erythromycin 500mg qds 7 days
Last 2 pref in HIV

22
Q

Treatment for donovanosis

A

Azithromycin 1g weekly or 500mg daily for 3 weeks or until ulcers healed

Alternative
Co-trimoxazole 160/800mg bd
Doxycycline 100mg bd
Erythromycin 500mg qds (in pregnancy) 
Gentamycin 1mg/kg 8hrly
23
Q

Treatment for PID

A

Ceftriaxone 1g IM plus doxycycline 100mg bd plus metronidazole 400mg bd for 14 days

2nd line:
Ofloxacin 400mg bd plus metronidazole 400mg bd for 14 days (can use levofloxacin 500mg od)

Moxifloxacin 400mg od for 14 days

24
Q

Alternative treatment for PID

A

Ceftriaxone 1g plus Azithromycin 1g per week 2 weeks

25
Q

Inpatient treatment for PID

A

IV ceftriaxone 2g daily plus IV doxycycline 100mg bd followed by oral doxy and metro for a total of 14 days

IV clindamycin 900mg daily plus IV Gentamycin (2mg/kg loading, 1.5mg/kg tds) followed by clindamycin 450mg qds or doxy plus metro total 14 days

26
Q

Treatment for LGV

A 
Doxycycline 100mg bd for 21 days
or
Erythromycin 500mg qds 21 days
or
Azithromycin 1g weekly for 3 weeks

Alternative
consider at least 2 weeks of oflox or moxiflox

27
Q

Treatment for EO STI related

A

Ceftriaxone 1g IM plus doxycycline 100mg bd 10-14 days

If micro NG
Doxycycline 100mg bd 10-14 days
or
Ofloxacin 200mg bd 14 days

28
Q

Treatment for EO probably enteric organism

A

Ofloxacin 200mg bd 14 days
or
Ciprofloxacin 500mg bd 10 days

29
Q

Treatment for incubating STS or epidemiological tx

A

Benzathine penicillin 2.4 MU im

Doxycycline 100mg bd 14 days

Azithromycin 2g stat

30
Q

Treatment for early STS

A

Benzathine penicillin 2.4 MU im single dose

Alternative
Procaine penicillin G 600 000 im 10 days
Doxycycline 100mg bd 14 days
Ceftriaxone 500mg IM 10 days
Amoxycillin 500mg qds plus probenecid 500mg 14 days
Azithromycin 2g stat or 500mg od 10 days
Erythromycin 500mg qds 14 days
31
Q

Treatment for late latent, CV and gummatous STS

A

Benzathine penicillin 2.4 MU IM weekly for 3 weeks

Alternative
Procaine penicillin G 600 000 im 14 days
Doxycycline 100mg bd 28 days
Amoxycillin 2g tds plus probenecid 500mg qds 28 days

32
Q

Treatment for neurosyphilis

A

Procaine penicillin 1.8 - 2.4 MU IM od plus probenecid 500mg qds 14 days
or
Benzyl penicillin 10.8-14.4g 4 hrly 14 days

Alternative
Doxycycline 200mg bd 28 days
Amoxycillin 2g tds plus probenecid 500mg qds 28 days
Ceftriaxone 2g IM od 10-14 days

33
Q

Treatment of early syphilis in pregnancy

A

Benzathine penicillin 2.4 MU single dose 1st and 2nd trimesters
If 3rd trimester 2 doses a week apart

Alternative
Procaine penicillin G 600 000 im 10 days
Ceftriaxone 500mg IM 10 days
Amoxycillin 500mg qds plus probenecid 500mg qds 14 days

No longer recommended in pregnancy due to high risk treatment failure and CS
Azithromycin 2g stat or 500mg od 10 days
Erythromycin 500mg qds 14 days plus evaluation and treatment neonates at birth with penicillin

34
Q

Treatment of late syphilis in pregnancy

A

As non pregnant doxycycline contraindicated

35
Q

Treatment syphilis in HIV

A

As appropriate per stage as non HIV

36
Q

When do you use steroids alongside syphilis treatment?

A

For CV and neuro syphilis

40-60mg prednisone OD 3 days starting 24 hrs before antibiotics

37
Q

What is initial drug treatment for HSV?

A

5 day course
Aciclovir 400mg tds
Valaciclovir 500mg bd

Alternative
Aciclovir 200mg 5xday
Famciclovir 250mg tds

38
Q

What are the short course treatments for episodic HSV?

A

Aciclovir 800mg tds 2/7
Famciclovir 1g bd 1 day
Valaciclovir 500mg bd 3/7

39
Q

Suppressive regimens for HSV (6+ episodes per year)

A 
For 6-12 months 
Aciclovir 400mg bd (^tds) 
Aciclovir 200mg qds (^5xday)
Famciclovir 250mg bd (^tds) 
Valaciclovir 500mg od (^bd)

^increase frequency of dosage if breakthrough episodes

40
Q

Mgt of HSV in HIV

A

Aciclovir 400mg 5xday 7-10 days
Valaciclovir 500mg-1g bd 10 days
Famciclovir 250-500mg tds 10 days

Should be continued until all lesions re-epithelialised

DipGUM (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions