STI'S Flashcards
What is the name of the bacteria which causes Chlamydia
Chalmydia trachomatis
What are the two different lifestyles of Chalmydia trachomatis?
Elementary body: Outside host cells
Reticulate body: Intracellular growth
What serovars of Chlamydia will cause UTI’s?
D,K
What symptoms do men suffering with chlamydia get?
Light discharge, Pain in urination
Can be asymptomatic
What symptoms do women suffering with chlamydia get?
Infection of the cervix
Can be asymptomatic
Why can’t the beta-lactam class of antibiotics be used for treatment?
The bacteria has no peptidoglycan to target
What type of antibiotics are given to treat chlamydia?
Tetracyclines
What bacteria causes Syphilis?
Treponema Pallidum
Why is syphilis usually a rare infection?
Bacteria is very slow growing and has poor survival outside the cell
- Requires tissue abrasions from sexual contact
What is the usual progression path for a syphilis infection?
- Chancere (open sores)
- Rash and fever
- No symptoms/asymptomatic
- Cardiac/nerve disease
Why was the 1910 drug Salvarsan effective against syphilis?
It killed anything it came into contact with effectively
What is the current treatment for Syphilis infections?
High levels of penicillin for multiple weeks
What bacteria causes Gonorrhoea?
Neisseria gonorrhoeae
What are the symptoms of a Gonorrhoea infection?
Thick uretheral discharge
Pain on urination
Why is it so difficult to generate a vaccine against Gonorrhoea?
Sialylation of LPS
Gonococci produce sequence variants making vaccines impossible
