STI Part 2 Flashcards
Syphilis transmissibility
highly transmissible through kissing, lesions ever when asym
Syphilis - sys or localized disease
sys
Stages of syphilis
primary (asym or chancre) - secondary - latent (asym) (if less then 2 year resoltuion, if more then 2 year can become tertiary or have resolution)
Syphilis and pregnancy
pregenancy can be asym or congenitial infection of ababy
characterist of primary syphilis
chancre, lesion
charcter of secondary syphilis
rash , fever, malaire , haedches, uveitus and retinitis
charcteristics of latent syphilis
early ( infectious)
late (non infectious
- we tell via seroly and are poistive for life
characteristics of tertiary syphilis
- cardiovascular syphilis
- neurosyphilis
-gumma ( destruction of any organ)
neurosyphilis features
sym or asym
- vertigo, headaches, loss of hearing(can be permanent), personality cahnges, dementia and ataxia
what seroly marker are we looking for syphilis
- treponemal tests (positive for life)
however goes down in volume as resolution of condition - also look at reducing RPR or VDRL titres
syphilis testing what to keep in mind
false negatives are common in primary so retets in 2-4 weeks if suspected or suspious case
syphilis successful treament mean what lab value wise?
RpR and VDRL titre go down
when is a lumbar indicated in syphilis
- ocular syphilis
- neurosyphilis
- congenital syphilis
- tx failure
syphilis Tx for primary, secondary or early latent
and prego!
benzathine penicillin G IM - single dose
1-2 weekly doses recom
syphilis tc for latent, tertiary not neuro
benzathine penicillin G IM weekly for 3 weeks
syphilis tx for neurosyphilis
Penicillin G IV q 4h for 10-14 days (in hospital)
syphilis follow up
primary or secondary: 1, 3, 6, 12 post tx
latent and tertiary: 12 and 24 months post tx
syphilis serologic repsonse
primary
4 fold at 6 months
8 fold at 12 month
16 fold at 24 months
secondray
8 fold at 6 month
16 fold at 12 month
tertiary
4 fold at 12
HPV how cmmon
most common STI
HPV high risk
types 16 and 18 cause cervical anogenitla and some head and anck cancers
HPV low risk types and effect
warts - usualy 6 and 11
HPV transmissioon
skin to skin
How do we prevent HPV
- condom
- pap smears
- HPV vax
HPV vax
cervarix (HPV2)
gardasil (HPV9)
cervarix (HPV 2) portects agaisnt
types 16 and 18
gardasil 9 (HPV9) portects against
a bunch of types
what does immunization do?
protect against cancer and warts
vax schdule: girls 9-14
cervarix or gardasil
- 2 or 3 doses
vax schdule: women and girlks over 15
cervarix or gardasil
- 3 doses
Vax schdule: boys 9-14
gardenasil
- 2 or 3 doses
Vax schdule: boys 15 plus, and men
gardensail
- 3 doses
Anogenital warts caharcterist
can be asym, can cause bleeding, internal or external, self limiting, reoocurance is common
anogenital warts tx self applied or clinician applied?
self - if extrnal
clincicain if external or prego
anogenital warts topcial creasm
imiquimod
podophyllitoin
sinecatechins
anaogenital cream to use cautiously in immuncomprised (immune rsponse modulator)
imiquimod
whihc topical can you leave on and not have to wash off
podophyllitoin
sinecatechins
