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KMK - Ocular Disease > Stevens-Johnson Syndrome > Flashcards

Stevens-Johnson Syndrome Flashcards

1
Q

Stevens-Johnson is what type of hypersensitivity reaction?

A

Type 3

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2
Q

SJS affects what?

A

Mucous membranes, mostly oral and ocular

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3
Q

What is the most common cause of drug induced SJs?

A

Sulfonamides

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4
Q

What drugs may induce SJS?

A 
Sulfonamides
Phenytoid
Penicillin
Aspirin
Barbiturates
Isoniazid
Tetracyclines
NSAIDs
Immunization vaccines
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5
Q

What infectious agents may induce SJS?

A

Herpes simplex
Mycoplasma pneumoniae
Adenovirus
Strep

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6
Q

What makes up the systemic prodrome of SJS?

A 
Fever
Malaise
Headache
Nausea
Vomiting
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7
Q

What follows the SJS prodrome?

A

“Bull’s eye” skin lesions
Papules on palms and soles
Ocular lesions

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8
Q

What ocular lesions are involved with SJS?

A

Severe, bilateral, diffuse conjunctivitis with pseudomembranes
Bacterial conjunctivitis progressing to endopthalmitis

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9
Q

What in endophthalmitis?

A

Inflammation of the internal coats of the eye

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10
Q

What are the corneal pathologies that may be seen in SJS?

A

Ulcers
Neo
Scarring
Possible perforation

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KMK - Ocular Disease (20 decks)

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