Ocular Cicatricial Pemphigoid Flashcards
1
Q
Which gender more commonly suffers from ocular cicatricial pemphigoid?
A
Female (2:1)
2
Q
What is the average age of diagnosis of OCP?
A
65
3
Q
OCP is a chronic disorder of what?
A
Mucous membranes
4
Q
OCP is what type of hypersensitivity reaction?
A
Type II
5
Q
OCP is characterized by autoantibodies being directed at what?
A
Basement membrane of mucous membranes
6
Q
OCP can be drug induced by what 3 drugs?
A
Timolol
Epinephrine
Pilocarpine
7
Q
What are the typical symptoms of OCP?
A
Non-specific symptoms including: Redness Dryness FBS Decreased VA
8
Q
What are the typical signs of OCP?
A
Conj fibrosis and scarring (white striae)
Symblepharon (typically bilateral)
Ankyloblepharon
9
Q
What structures are often destroyed in OCP?
A
Goblet cells Meibomian glands Glands of Karuse Glands of Wolfring Ducts of main lacrimal gland
10
Q
What are the common late stage findings of OCP?
A
Entropion Trichiasis Corneal ulceration Corneal neo Corneal keratinization
