Steroid Receptor (Ant)agonists

Question 1

Glucocorticoid agonist

Answer 1

Prednisolone

Beclomethasone

Question 2

Glucocorticoid antagonist

Answer 2

Mifepristone

Question 3

Mineralocorticoid agonist

Answer 3

Fludrocortisone

Question 4

Mineralocorticoid antagonist

Answer 4

Spironolactone

Question 5

Oestrogen agonist

Answer 5

Ethinylestradiol

Question 6

Oestrogen antagonist

Answer 6

Tamoxifen

Metabolised by CYP2D6

Question 7

Progestagen agonist

Answer 7

Norethisterone

Question 8

Progestagen antagonist

Answer 8

Danazol

Question 9

Function of prednisolone

Answer 9

Glucocorticoid agonist

Question 10

Function of beclomethasone

Answer 10

Glucocorticoid agonist

Anti inflammatory/immunosuppressive used in treatment of asthmatics

Question 11

Mifepristone function

Answer 11

Glucocorticoid antagonist
Abortifacient
Progestagen partial agonist

Question 12

Fludrocortisone function

Answer 12

Mineralocorticoid agonist

Can replace aldosterone in Addison’s

Question 13

Spironolactone function

Answer 13

Mineralocorticoid antagonist

Diuretic

Question 14

Ethinylestradiol function

Answer 14

Oestrogen agonist

HRT

Question 15

Tamoxifen function

Answer 15

Oestrogen antagonist

Treatment of breast cancers

Question 16

Norethisterone function

Answer 16

Progestagen agonist

Contraception

Question 17

Danazol function

Answer 17

Progestagen antagonist

Endometriosis treatment

Question 18

Androgen agonist

Answer 18

Testosterone

Question 19

Androgen antagonist

Answer 19

Glutamine

Question 20

Testosterone function

Answer 20

Androgen agonist
Replacement therapy (check)

Question 21

Flutamide function

Answer 21

Androgen antagonist

Treatment of prostate cancer