Sterile Compounding I

Question 1

aseptic

Answer 1

without organisms

i.e. sterile

Question 2

beyond use date (BUD)

Answer 2

is the date after which a compounded medication should not be used

• dates are typically short
(days, weeks, months)
• are assigned to compounded drug products

Question 3

What is the technical term for a pharmacy clean room?

Answer 3

Buffer area

Question 4

What chapter of the United States Pharmacopoeia (USP) is concerned with compounded sterile products?

Answer 4

USP Chapter 797

• ultimate goal of the chapter is to protect patients from receiving contaminated infusions

Question 5

What is a “critical site?”

Answer 5

is an opening that provides a pathway between the container of a sterile product and the environment

Question 6

Sterile alcohol swabs are soaked in what type of alcohol?

Answer 6

70% isopropyl alcohol

Question 7

What type of container must be used for the disposal of needles?

Answer 7

red sharps container

Question 8

laminar airflow hood (LAFH)

Answer 8

to create an environment with a very low concentration of particles & microorganisms in the air so that formulations safe enough for human infusion can be prepared

• prior to use, must be cleaned with 70% isopropyl alcohol , when in use- cleaned every 30mins+turned on
• work at least 6in inside
• avoid placing hands/objects behind the materials you are working with because you want to prevent airflow obstruction

Question 9

How many air filters is a LAFH equipped with?

Answer 9

2 air filters

1 regular filter & 1 HEPA filter

Question 10

What is a HEPA filter?

Answer 10

“High Efficiency Particulate Air”

• remove 99.97% of particles from the air that are 0.3 micrometers or larger
• don’t wipe/spray filter with alcohol

Question 11

What type of hood should be used to compound chemotherapy infusions?

Answer 11

biological safety cabinet