steps in DNA replication 1 Flashcards

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1
Q

DNA synthesis begins at the

A

origin of replication (modeled as oriC) in prokaryotes

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2
Q

formation of a replication fork must occur:

A

zone of unwound DNA where DNA polymerization is occuring

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3
Q
  1. DNA topoisomerases, like DNA gyrase, remove the
A

supercoils in the DNA to create linear DNA

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4
Q
  1. DNA is nicked
A

DnaA proteins bind to the origin and cleave the hydrogen bonds between complementary strands

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5
Q
  1. Next DNA helicase acts to unwind
A

the DNA for a short distance and expose it as two single-stranded regions

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