Step 1 Flashcards
1
Q
How to remember encapsulated organisms?
A
Some Killers Have Perfectly Nasty Capsules S. pneumo Klebsiella H flu Pseudomonas Neisseria meningitidis Cryptococcus neoformans
2
Q
Who gets encapsulated infections?
A
Asplenic patients
3
Q
What do fluoroquinolones cover? What is their MOA?
A
Broad spectrum with both gram positive and gram negative coverage
Cover pseudomonas
Work by inhibiting DNA synthesis the bacterial topoisomerase protein.
4
Q
What are the anti-psuedomonal penicillins?
A
Ticeracillin
Piperacillin
5
Q
Which cephalosporin covers pseudomonas?
A
Ceftazidime
6
Q
What does aztreonam cover?
A
Gram negative rods
Can be used in patients who are penicillin allergic
7
Q
Why is trimethoprim commonly given with sulfamethoxazole as TMP-SMX?
A
These agents inhibit folic acid synthesis at different steps, meaning their combination is synergistic
