STD

Question 1

Signs/Symptoms of Herpes Simplex Virus

Answer 1

Burning or painful erythema, papules, multiple vesicular or ulcerative lesions
HSV 1 - oral
HSV 2 - genital

Question 2

Diagnosis of Herpes Simplex Virus

Answer 2

PCR of genital specimens (Expensive test of choice). Serologic assays. Direct flourescent antigent. Culture.

Question 3

Treatment of Herpes Simplex Virus

Answer 3

Antiviral Drugs
1st clinical episode, treat for 7-10 days: Acyclovir 400 mg tid. Acyclovir 200 5x/day. Famciclovir 250 tid. Valacyclovir 1g bid.

Suppresive therapy: for 6+ recurrences/year: Acycovir 400-800 BID. Famciclovir 250-500 BID. Valcyclovir 1g QD.

Question 4

Pregnancy and Herpes Simplex Virus

Answer 4

Dont have sex with sero-positive partners in 3rd trimester

Herpes present at labor –> C Section!

Question 5

Primary Syphilis

Answer 5

Signs: painless single papule. Painless clean ulcer with smooth base and firm raised borders. Multiple chancre in HIV pts. Painless lymphadenopathy.
Labs: Darkfield exam

Question 6

Seconadry Syphilis

Answer 6

Signs: Macular/maculaopapular/papular/pustular syphilides (palms and soles) Condyloma lata. Mucus patches. Constitutional symptoms (fever, malaise, weight loss, pharinitis, arthralgia). CNS involvement.

Question 7

Condyloma acuminatum TX

Answer 7

podophyllin resin. purified podophyllotoxin. 5-fluorouracil. surguery. cryotherapy. electrocoagulation. laser therapy. intralesional inferferon-alpha. imiquimod. 3% cidofovir.

Question 8

Tertiarty Syphilis

Answer 8

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