STD Flashcards

1
Q

Infectious agent of gonorrhea

A

Neisseria gonorrheae

gram - intracellular diplococci

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2
Q

Man presenting with yellow, creamy, profuse discharge from penis with burning

A

Gonorrhea

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3
Q

Ways to dx gonorrhea

A

Gold Standard: culture
gram stain
can also do NAAT/PCR

-urine tests available, not as good

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4
Q

Treatment for gonorrhea

A

Ceftriaxone 250mg IM once

+ Azithromycin 1g PO once

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5
Q

If patient is allergic to traditional tx, what can be used for gonorrhea?

A

Azithromycin 2g PO once

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6
Q

Infectious agent of chlamydia

A

C. trachomatis

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7
Q

MC bacterial STD in men and women is

A

Chlamydia

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8
Q

Man with dysuria and >5 WBCs on urine dipstick is suggestive of

A

Urethritis- likely chlamydia

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9
Q

Pt with conjunctival redness, R knee arthritis, and dysuria

A

Reiter’s syndrome

linked to chlamydia

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10
Q

What antibiotic specifically treats chlamydia

A

Azithromycin

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11
Q

Risk factors for PID include

A
nulliparity
AA
multiple partners
douching
smoking
IUD
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12
Q

Infectious agent of PID

A

Starts with GC/Chlamydia but is polymicrobial infection

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13
Q

When is PID most common

A

around menses

-from disruption of natural barriers

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14
Q

Unilateral adnexal pain, purulent cervical discharge, fever, chills, bleeding, post-coital bleeding, dyspareunia, dysuria
Chandelier sign

A

Pelvic Inflammatory Disease

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15
Q

To dx PID

A

Its a clinical diagnosis
Pt has signs of STD and signs of inflammation

US- if concerned about ectopic pregnancy or abscess

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16
Q

Treatment of outpatient PID

A

Ceftriaxone 250 IM once (gets gonorrhea)
Doxycycline 100mg PO BID x 14 days
+/- Flagyl 500mg PO BID x 14 days

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17
Q

Treatment of TOA

A

requires surgical or transcutaneous debridement

follow up US to assess for resolution

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18
Q

Infectious agent of syphilis

A

Treponema pallidum

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19
Q

Risk of acquiring syphilis when contacted

A

50%

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20
Q

Major sxs of secondary syphilis

A

Rash, “copper penny lesions”

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21
Q

What are condyloma latas and when do they occur

A

Weeping papules in moist skin regions

During secondary syphillis

22
Q

Presentation of tertiary sphyillis

A

Gummas- granulomatous tumors of skin, liver, bone
Aortic aneurysms
CNS- dementia, psychosis, polyneuropathy,focal
*Argyl Robinson pupil

23
Q

An argyle robinson pupil does what

A

accommodates but doesn’t react

24
Q

Can dx syphilis via

A
Dark Field Microscopy
-useful early, not great on mouth
VDRL of RPR for SCREENING
-may be a lot of false (+)
-If + get FTA-ABS
FTA-ABS
-once positive, then + for life
25
Q

Neursyphilis dx

A
clinical findings +
LP:
 -elevated protein
 -lymphocytic pleocytosis
 -CSF VDRL may be +
 -CSF FTA-ABS +
26
Q

Tx of primary, secondary, and early latent syphilis

A

Benzathine Penicillin G 2.4 million units IM once

if unsure, will do it over 3 weeks

27
Q

Primary, secondary, and early latent syphilis treatment in PCN allergy pt

A

Doxycycline for ~ a month depending on the stage

28
Q

When is FU done for syphilis treatment

A

Serological testing done at 6 and 12m that include RDR titers

29
Q

Neurosyphilis tx

A

3 options:
Aqueous PCN G 24mill units IV daily
Procaine penicillin 2.4 mill units IM daily w/probenicid
Ceftriaxone 2g IV daily

  • all for 2 weeks
  • f/u with LP for 6m
30
Q

What is Jarisch-Herxheimer reaction

A

complication of treatment of syphilis. Is self limiting. hypersensitivity reaction of host
rapid destruction of syphilis bacteria and release of lipoproteins into serum
leading to systemic hypersensitivity rxn
-usually within first 24hrs tx
-fevers, chills, HoTN

31
Q

How do you tx Jarisch-Herxheimer reaction

A

antipyretics

continue abx unless syphilitic laryngitis, auditory neuritis, or labryinthitis develops

32
Q

Syphilis in pregnancy treated with

A

PCN only

  • no doxycycline w/developing fetus
  • require desensitization if allergic
33
Q

what are rhagades

A

scars around mouth or nose seen in congenital syphilis

34
Q

what are Hutchinson teeth?

A

permanent upper incisor that are peg shaped with a central notch seen in congenital syphilis

35
Q

Influencing factors determining if pt gets genital herpes clinically

A

immune status, viral serotype, females more predisposed

36
Q

Gold standard to dx HSV

A

Tissue culture= Gold Standard

Tzank Smear- multinucleated giant cells

-More likely to get swab of sore and DFA test

37
Q

Characteristic sign HSV encephalitis

A

Temporal lobe enhancement on MRI

38
Q

When is antibody testing used for HSV diagnosis

A

To document seroconversion only!

Does not distinguish active or latent infection, or predict recurrences

39
Q

What HPV strains are most commonly associated with genital warts

A

6 & 11

40
Q

What HPV strains are most commonly associated with cervical cancer/neoplasia

A

16 & 18

Also ( 31,33,35)

41
Q

What age group is indicated to receive HPV prevention Gardasil

A

Females and males 9-26yrs

males 22-26 immunocomp

42
Q

Causitive agent of chancroid

A

Haemophilus ducreyia

43
Q

Painful necrotizing genital ulcers with inguinal LAD

A

Chancroid

44
Q

Causative agent of lymphogranuloma venereum

A

C. trachomoatis

Serotypes L1,L2, L3

45
Q

Proctitis with bleeding, tenesmus, purulent discharge, rectal ulcers, and constitutional symptoms

A

LGV- lymphogranulma venereum

46
Q

To dx LVG

A

Clinical findings with NAAT for confirmation with genotyping for serotypes

47
Q

Causative agent of Molluscum

A

poxviurs

48
Q

Causative agent of Trichomonas

A

flagellated protozoal T. vaginalis

49
Q

Copious frothy green/yellow discharge with odor and pruritis

Strawberry cervix

A

Trichomonas

50
Q

Main way to dx Trichomonas

A

Wet Mount showing motile trichomonads

51
Q

Tx for Trichomonas

A

Flagyl
2 different length options 1 day or 7 days
if unsure if BV, do 7 day dose

52
Q

Which type of hepatitis is likely to be transmitted as STD?

A

Hep B