Infectious Disease Overview

Question 1

MC travel related causes of febrile illness

Answer 1

Malaria
Enteric- typhoid, shigella
Hepatitis
Amebic- giardia

Question 2

Streptococcus appearance

Answer 2

Gram +

cocci in pairs and chains

Question 3

What lancefield criteria is MC for strep

Answer 3

Group A

Question 4

Which strep subgroup doesn’t possess Lancefield antigens?

Answer 4

Strep mitis

Question 5

When are enterococcus pathogenic?

Answer 5

Once they enter the blood stream

Question 6

how are enterococcus spread?

Answer 6

Person to person

normally found in GI and female GU as normal flora

Question 7

Tx for E. faecium

Answer 7

Linezolid, Daptomycin, Quinupristin-Dalfopristin - Synercid

Question 8

Tx for E. faecalis

Answer 8

Linezolid, Daptomycin, Quinupristin-Dalfopristin

• NOT syndercid

Question 9

MCC impetigo

Answer 9

Group A Strep- strep pyogenes

Question 10

MC organism in necrotizing fasciitis

Answer 10

MC polymicrobial

GAS, S aureus…

Question 11

Rapidly spreading erythematous lesion

with pain out of proportion to PE consider

Answer 11

Necrotizing Fasciitis

Question 12

TX for toxic shock

Answer 12

SX consult ASAP
Abx
Specific IVIG to neutralize toxin
~pressors, ventilation, transfusions, fluids

Question 13

Cause of botulism

Answer 13

Clostridium botulinum

Question 14

Description of C. botulinum

Answer 14

anaerobic, spore forming bacillus found in soil

Question 15

How to dx botulism

Answer 15

Toxin ID via mouse antiserum after inoculation of patient’s serum into the mouse

Question 16

Treatment of botulism

Answer 16

supportive

CDC has anti-toxin available

Question 17

Cause of Anthrax

Answer 17

Bacillus anthracis

Question 18

What organism are likely carriers of anthrax

Answer 18

sheep, goats, horses, swine zoonosis

Question 19

Cause of cholera

Answer 19

toxin of Vibrio cholera activating adenylyl cyclase

Question 20

profuse rice water diarrhea think

Answer 20

Cholera- Vibrio cholera

Question 21

Treatment for Cholera

Answer 21

Fluids- PO or IV-lactated ringers
Bactrim or Quinolone (test for resistance)
Temporary vaccine

Question 22

opisthotonos

Answer 22

severe hyperextension/spasticity

-seen with tetanus, TBI, and cerebral palsy

Question 23

Cause of tetanus

Answer 23

Clostridium tetani

neurotoxin- tetanospasm

Question 24

SXS of fever, pea soup, bradycardia, and pink popular rash on trunk

Answer 24

Enteric fever (Typhoid)
-Salmonellosis

Question 25

Treatment of typhoid enteric fever

Answer 25

Fluoroquinolone

Question 26

contact with reptiles think...

Answer 26

Salmonellosis gastroenteritis

Question 27

Shigella HLA

Answer 27

HLA- B27 - reactive arthritis

Question 28

grey tenacious membrane of tonsils and pharynx

Answer 28

Diphtheria

Question 29

Neisseria gonorrhea gram stain results

Answer 29

Gram – intracellular diplococcus | Requires Thayer-martin agar to grow

Question 30

Treatment of Neisseria gonorrhea

Answer 30

Ceftriaxone, Cefixime, 2nd line – Azithromycin 2gm x 1

Question 31

Neisseria meningitides culture will test positive for

Answer 31

the enzyme cytochrome C oxidase

Question 32

College freshman living in dorm presents with n/v and stiff neck

Answer 32

Neisseria meningitidis

Question 33

Waterhouse-Friderishsen syndrome

Answer 33

acute adrenal hemorrhage | -Neisseria meningitidis

Question 34

Close contacts of pt with Neisseria meningitidis should receive

Answer 34

Rifampin alternative: Cipro

Question 35

Prevention of Neisseria meningitis

Answer 35

MCV4 vaccine

Question 36

Ehrlichiosis gram stain

Answer 36

Gram - obligate intracellular

Question 37

Blood smear showing Morula

Answer 37

Ehrlichiosis

Question 38

Treatment for Ehrilichiosis

Answer 38

Doxycycline | Rifampin in prego/peds

Question 39

from birds/parrots

Answer 39

Chlamydia psittaci

Question 40

Cat bites

Answer 40

Pasturella | tx with Augmentin

Question 41

Human bites

Answer 41

Eikinella | tx with Augmentin

Question 42

Cat scratch disease

Answer 42

Bartonella henselae

Question 43

spread via body lice and OI in AIDS pts causing bacillary angiomatosis

Answer 43

Bartonella guitana

Question 44

HHV 5 is

Answer 44

CMV

Question 45

HHV 4 is

Answer 45

EBV

Question 46

West Nile Virus is a

Answer 46

Flavivirus

Question 47

HSV1 is

Answer 47

common cold sore

Question 48

HSV2 is

Answer 48

genital herpes

Question 49

which HSV is more likely to cause herpanginga/ pharyngotonsillitis

Answer 49

HSV1 ddx viral: HSV2, enterovirus 71