Statistics Flashcards

1
Q

what are P values?

A

numbers between 0-1 that quantify how confident we should be that drug A is different from drug B

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2
Q

which P-value shows the most confidence?

A

P values closer to 0

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3
Q

what is the accepted P-value?

A

0.05% (95%)

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4
Q

a small p-value when there there is no difference is called…?

A

a false positive

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5
Q

what are examples of dichotomous variables? (2)

A
  • employed vs unemployed
  • has disease vs does not have disease
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6
Q

what is a reference population?

A

extracting a sample of a larger population

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7
Q

what is the null hypothesis?

A

a statement that there is no relationship between the two variables that are tested

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8
Q

what is the confidence interval?

A

range of values in which the actual value lies

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9
Q

what is a type 1 error?

A

rejecting the null hypothesis when it is true

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10
Q

what is a type 2 error?

A

accepting the null when it is false

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11
Q

what does the box size represent on a forest plot?

A

the weight of the study

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12
Q

what does the vertical line represent on a forest plot? (2)

A
  • the line of no effect
  • intervention has had no effect on outcome
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13
Q

what does the horizontal line represent on a forest plot?

A

confidence interval

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14
Q

what does the diamond represent on a forest plot?

A

the total meta-analytic result

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15
Q

what does the peak of the diamond represent on a forest plot?

A

optimal result

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16
Q

what does the sides of the diamond represent on a forest plot?

A

confidence intervals

17
Q

what is heterogenity?

A

differences between studies not due to chance

18
Q

what are the types of heterogenity? (2)

A
  1. clinical
  2. statistical
19
Q

what test is used for heterogenity?

A

chia-squared test

20
Q

what is a study population?

A

small sample of the entire population

21
Q

what is the confidence interval?

A

intervals computed from the sample data, which were the study repeated multiple times, would contain the true effect 95% of the time

22
Q

what is relative risk?

A

comparing the probability of the event occurring to all possible events considered in the study

23
Q

how is relative risk calculated?

A

incidence in exposed / incidence in non exposed

24
Q

what does it mean if the relative risk = 1?

A

incidence in exposed group is the same in non exposed

25
Q

what does it mean if the relative risk > 1?

A

incidence in exposed group is greater than in non exposed

26
Q

what does it mean if the relative risk < 1?

A

incidence in exposed group is lower than in non exposed

27
Q

“the further the relative risk is from 1…

A

…the stronger the association”

28
Q

which study can you not use relative risk in?

A

case control

29
Q

what is the odds ratio?

A

a measure of how strongly an event is associated with exposure

30
Q

how do you calculate odds ratio?

A

odds the case was exposed / odds the control was exposed

31
Q

what does it mean if the odds ratio = 1?

A

exposure is not associated with disease

32
Q

what does it mean if the odds ratio > 1?

A

exposure is positively associated with disease

33
Q

what does it mean if the odds ratio < 1?

A

exposure is negatively associated with the disease

34
Q

“the further the odds ratio is from 1…

A

…the stronger the association”

35
Q

which studies can you use odds ratios in? (2)

A
  • cohort
  • case controls