Staging/ incidences Flashcards
Timing of delivery in preeclampsia?
inability to control maternal blood pressure despite using 3 or more classes of antihypertensives in appropriate doses
- maternal pulse oximetry less than 90%
- progressive deterioration in liver function, renal function, haemolysis, or platelet count
- ongoing neurological features, such as severe intractable headache, repeated visual scotomata, or eclampsia
- placental abruption
- reversed end-diastolic flow in the umbilical artery doppler velocimetry, a nonreassuring cardiotocograph, or stillbirth
Spread of the growth to –> distant organs
Extend beyond true pelvis
Stage IV B cervical cancer
Tumor invades bladder and/or bowel mucosa, and/or distant metastases
stage IV uterine cancer
Extended beyond the true pelvis
or has involved (biopsy proven)
the mucosa of the bladder or rectum.
bullous edema, as such, does not permit a case to be allotted to Stage IV.
Stage IV cervical cancer
Distant metastasis,
including intra-abdominal metastases and/or inguinal nodes
Stage IVB uterine cancer
Distant metastasis excluding peritoneal metastasis
Stage IV - ovarian cancer
Tumor of any size fixed to bone,
or fixed, ulcerated lymph node metastases,
or distant metastases
Stage IV vulva cancer
The cancer has spread to distant organs such as the lungs or bones (M1).
It can be any size
and might or might not have grown into nearby structures or organs (Any T)
It might or might not have spread to nearby lymph nodes (Any N)
Stage IV B vagina cancer
Tumor invasion of bladder and/or bowel mucosa
Stage IVA uterine cancer
Extend beyond true pelvis
Spread of the growth to –> adjacent pelvic organs
Stage IVA cervical cancer
Parenchymal metastases
metastases to extra-abdominal organs
(including inguinal lymph nodes
& lymph nodes outside of the abdominal cavity)
Stage IVB ovarian cancer
distant metastases
Stage IVB vulva cancer
Disease fixed to pelvic bone,
or fixed or ulcerated regional lymph node metastases
stage IVA vulva cancer
The cancer is growing into the bladder or rectum or is growing out of the pelvis (T4)
It might or might not have spread to lymph nodes in the pelvis or groin (inguinal area) (Any N).
It has not spread to distant sites (M0)
Stage IV A vaginal cancer
Pleural effusion with positive cytology
Stage IVA ovarian cancer
Regional lymph node metastases
with extracapsular spread
Nonfixed, nonulcerated lymph nodes
Stage IIIC vulva cancer
The cancer is growing into the pelvic wall,
and/or growing into the lower one-third of the vagina
and/or has blocked the flow of urine (hydronephrosis), which is causing kidney problems (T3)
It has not spread to nearby lymph nodes (N0) or to distant sites (M0)
Stage III vagina cancer
Macroscopic peritoneal metastasis
beyond the pelvis
more than 2 cm in greatest dimension,
with or without metastasis to the retroperitoneal lymph nodes
(includes extension of tumour to capsule of liver and spleen without parenchymal involvement of either organ)
Stage IIIC ovarian cancer
Involvement of pelvic and/or para-aortic lymph nodes (including micrometastases),
irrespective of tumor size and extent
Stage IIIC cervical cancer
Stage IIICp - detected on pathology
Stage IIICr - detected on imaging
Liver capsule/ Spleen capsule
Stage IIIC Ovarian cancer
Positive para-aortic nodes with or without positive pelvic lymph nodes
Stage IIIC2 uterine cancer
Para-aortic lymph node metastasis
Stage IIIC2 cervical cancer
Tumor invades the
serosa of the corpus uteri
and/or adnexa
Stage IIIA uterine cancer
The carcinoma involves the lower third of the vagina,
with no extension to the pelvic wall
Stage IIIA cervical cancer
The cancer can be any size and might be growing into the pelvic wall, and/or growing into the lower one-third of the vagina and/or
has blocked the flow of urine (hydronephrosis), which is causing kidney problems (T1 to T3).
It has also spread to nearby lymph nodes
in the pelvis or groin (inguinal) area (N1) but not distant sites (M0)
Stage III vagina cancer
Vaginal involvement and/or parametrial involvement
Stage IIIB uterine cancer
Extension to the pelvic wall
and/or hydronephrosis or nonfunctioning kidney (unless known to be due to another cause)
Stage IIIB cervical cancer
Macroscopic peritoneal cancer >2cm
Beyond pelvis
Stage IIIC ovarian cancer
Positive pelvic nodes
Stage IIIC1 uterine cancer
Pelvic lymph node metastasis only
Stage IIIC1 cervical cancer
hydronephrosis
kidney problems
stage III vaginal cancer
Stage IIIB cervical cancer
Macroscopic peritoneal metastasis beyond the pelvis
up to 2 cm in greatest dimension,
with or without metastasis to the retroperitoneal lymph nodes
Stage IIIB Ovarian cancer
Regional lymph node metastases >5 mm
Nonfixed, nonulcerated lymph nodes
Stage IIIB vulva cancer
Microscopic extrapelvic (above the pelvic brim) peritoneal involvement
with or without positive retroperitoneal lymph nodes
Stage IIIA2 Ovarian cancer
Positive retroperitoneal lymph nodes only
(cytologically or histologically proven):
Metastasis > 10 mm
in greatest dimension
IIIA1-(II): Ovarian cancer
Tumor of any size
with disease extension to upper two-thirds of the urethra,
upper two-thirds of the vagina, bladder mucosa, rectal mucosa,
or regional lymph node metastases ≤5 mm
Nonfixed, nonulcerated lymph nodes
Stage IIIA vulva cancer
Positive retroperitoneal lymph nodes only
(cytologically or histologically proven):
Metastasis upto 10 mm
in greatest dimension
IIIA1 (i): ovarian cancer
Invasive carcinoma >5 mm depth of stromal invasion and ≤2 cm in greatest dimension
Invasive carcinoma with measured deepest invasion >5 mm; lesion limited to the cervix uteri with size measured by maximum tumor diameter
Stage IB1 cervical cancer
Stage IB cervical cancer
Invasive carcinoma ≤4 cm in greatest dimension
Involvement limited to the upper two-thirds of the vagina without parametrial involvement
Stage IIA1 cervical cancer
Stage IIA cervical cancer
Invasive carcinoma >2 and ≤4 cm in greatest dimension
Invasive carcinoma with measured deepest invasion >5 mm; lesion limited to the cervix uteri with size measured by maximum tumor diameter
Stage IB2 cervical cancer
Stage IB cervical cancer
The carcinoma invades beyond the uterus,
but has not extended onto the lower third of the vagina or to the pelvic wall
Stage II cervical cancer
The cancer has grown through the vaginal wall,
but not as far as the pelvic wall and is larger than 2.0 cm (4/5 inch) (T2b) = >2cm
It has not spread to nearby lymph nodes (N0) or to distant sites (M0)
Stage IIB vaginal cancer
regional lymph node metastases ≤5 mm
Nonfixed, nonulcerated lymph nodes
Stage III A vulva cancer
Positive retroperitoneal lymph nodes only
cytologically or histologically proven
Stage IIIA1: ovarian cancer
Tumor of any size with extension to upper part of
adjacent perineal structures,
or with any number of nonfixed, nonulcerated lymph node
Stage III vulva cancer
VTE incidence
2/ 10 000 — non pregnant women background risk
29/ 10 000 — pregnant
300 - 400/ 10 000 puerperium
Tumour involves one or both ovaries or fallopian tubes,
or peritoneal cancer,
with cytologically or histologically confirmed spread to the peritoneum outside the pelvis
and/or metastasis to the retroperitoneal lymph nodes
Stage III ovarian cancer
Tumour involves one or both ovaries or fallopian tubes
with pelvic extension
(below pelvic brim)
or peritoneal cancer
Stage II ovarian cancer
Above pelvic brim
Stage IIIA2 ovarian cancer
Below pelvic brim
Stage II ovarian cancer
Distal ureter injury
Local and/or regional spread of the tumor
Stage III uterine cancer
Retroperitoneal Lymph nodes positive
Stage III ovarian cancer
Tumor of any size
with extension to lower one-third of the urethra,
lower one-third of the vagina,
lower one-third of the anus
with negative nodes
Stage II vulva cancer
Macroscopic peritoneal metastasis
Stage IIIB ovarian cancer
Stage IIIC ovarian cancer
nonfixed, nonulcerated lymph node positive
Stage III vulva cancer
Extension and/or
implants on uterus
and/or fallopian tubes and/or ovaries
Stage II A ovarian cancer
With parametrial involvement
but not up to the pelvic wall
Stage IIB cervical cancer
Tumor invades cervical stroma, but does not extend beyond the uterus
Stage II uterine cancer
Parametrium
Stage IIB cervical cancer
Stage IIIB uterine cancer
lower one-third of the vagina
Stage II vulva cancer
- Extension to other pelvic intraperitoneal tissues
- Tumour involves one or both ovaries or fallopian tubes with pelvic extension (below pelvic brim) or peritoneal cancer
Stage IIB ovarian cancer
Stage II ovarian cancer
Microscopic extrapelvic (above the pelvic brim) peritoneal involvement
Stage IIIA2 ovarian cancer
The cancer has grown through the vaginal wall, but not as far as the pelvic wall and is no larger than 2.0 cm (4/5 inch) (T2a)
It has not spread to nearby lymph nodes (N0) or to distant sites (M0)
Stage IIA vaginal cancer
lower one-third of the anus
Stage II vulva cancer
Malignant cells in the ascites or peritoneal washings
Stage IC3: ovarian cancer
Nodes negative
Stage II vulva
The carcinoma involves the lower third of the vagina
and/or extends to the pelvic wall
and/or causes hydronephrosis or nonfunctioning kidney
and/or involves pelvic and/or para-aortic lymph nodes
Stage III cervical cancer
The cancer is only in the vagina
and is larger than 2.0 cm (4/5 inch) (T1b)
It has not spread to nearby lymph nodes (N0) or to distant sites (M0
Stage I vaginal cancer
Invasive carcinoma ≤4 cm in greatest dimension
Involvement limited to the upper two-thirds of the vagina without parametrial involvement
Stage IIA1 cervical cancer
Stage IIA cervical cancer
Lower one third of vagina
Stage IIIA cervical cancer
Stage IIIB endometrial cancer
Stage III of vaginal cancer
Stage II of vulva cancer
Extension to pelvic wall
Stage III B cervical cancer
Stage III vaginal cancer
Involvement limited to the upper two-thirds of the vagina
without parametrial involvement
Stage IIA cervical cancer
- Upper two-thirds of the vagina
- Lower one third of the vagina
Stage IIIA vulva cancer - upper 2/3 Stage IIA cervical cancer - upper 2/3 Stage III endometrial cancer - vagina Stage II vulva cancer - lower 1/3 Stage IIIA cervical cancer - lower 1/3
Surgical spill
IC1: ovarian cancer
Tumor size >2 cm
or
stromal invasion >1 mm
Tumor confined to the vulva
Stage IB vulva cancer
fallopian tube surface tumor
Stage IC2: ovarian cancer
tumour on ovarian surface
Stage IC2: ovarian cancer
Tumor confined to the vulva
Stage I vulva cancer
Invasive carcinoma >4 cm in greatest dimension
Involvement limited to the upper two-thirds of the vagina without parametrial involvement
Stage IIA2 cervical cancer
Stage IIA cervical cancer
Invasive carcinoma >4 cm in greatest dimension
Lesion limited to the cervix uteri with size measured by maximum tumor diameter
Stage IB3 cervical cancer
Stage IB cervical cancer
Tumor limited to one or both ovaries or fallopian tubes, with any of the following: capsule ruptured, surface tumor, surgical spill, malignant cells in ascites
Stage IC ovarian cancer
Tumour limited to both ovaries (capsule intact) or fallopian tubes;
no tumour on ovarian or fallopian tube surface;
no malignant cells in the ascites or peritoneal washings
Stage IB ovarian cancer
Invasion equal to or more than half of the myometrium
Stage IB uterine cancer
Invasive carcinoma:
with measured deepest invasion >5 mm
(greater than Stage IA);
lesion limited to the cervix uteri with size measured by maximum tumor diameter
Stage IB cervical cancer
Measured stromal invasion ≤3 mm in depth
Invasive carcinoma that can be diagnosed only by microscopy, with maximum depth of invasion ≤5 mm
Stage IA1 cervical cancer
Stage IA cervical cancer
Tumor confined to the vulva
Tumor size ≤2 cm and
stromal invasion ≤1 mm
Stage IA vulva cancer
No or less than half myometrial invasion
Stage IA uterine cancer
Measured stromal invasion >3 and ≤5 mm in depth
Invasive carcinoma that can be diagnosed only by microscopy, with maximum depth of invasion ≤5 mm
Stage IA2 Cervical cancer
stage IA cervical cancer
Tumour limited to one ovary (capsule intact) or fallopian tube;
no tumour on ovarian or fallopian tube surface;
no malignant cells in the ascites or peritoneal washings
Stage IA ovarian cancer
Tumor confined to the corpus uteri
Stage I uterine cancer
Micro-Invasive carcinoma:
that can be diagnosed only by microscopy, with maximum depth of invasion ≤5 mm
Stage IA cervical cancer
ovarian capsule intact
Stage IA ovarian cancer
stage IB ovarian cancer
The carcinoma is strictly confined to the cervix
extension to the uterine corpus should be disregarded
Stage I Cervical cancer
Tumour confined to ovaries or fallopian tube(s)
Stage I: ovarian cancer