Staging

Question 1

<2cm lesion confines to vulva

Answer 1

Stage IA

Question 2

> 2cm lesion confined to vulva or w/ stromal invasion

Answer 2

Stage 1B

Question 3

Lower 1/3 vagina, lower 1/3 urethra, anus + negative nodes - vular

Answer 3

stage II

Question 4

Lower 1/3 vagina, lower 1/3 urthera, anus + LN - vulvar

Answer 4

stage III

Question 5

Lower 1/3 vagina, lower 1/3 urthera, anus + LN 1 >5mm

Answer 5

Stage IIIA

Question 6

Lower 1/3 vagina, lower 1/3 urthera, anus + LN 2 >5mm

Answer 6

Stage IIIB

Question 7

Lower 1/3 vagina, lower 1/3 urthera, anus + LN w/ extracapsular spread - vulvar

Answer 7

Stage IIIC

Question 8

Tumor of any size w/ upper 2/3 vagina, upper 2/3 urethra, rectal mucosa, pelvic bones - Vulvar

Answer 8

Stage IVA

Question 9

microscopic tumor confined to cervix <3mm <7mm spread

Answer 9

Stage IA1

Question 10

microscopic tumor confined to cervic 3-5mm ,7mm spread

Answer 10

Stage IA2

Question 11

Visible cervical tumor <4cm

Answer 11

Stage IB1

Question 12

Visible cerivcal tumor >4cm

Answer 12

Stabe IB2

Question 13

Cervical Tumor extension to uterus but not to pelvic side wall

Answer 13

Stage II cervical

Question 14

cervical cancer w/o parametrial involvement

Answer 14

Stage IIA

Question 15

cervcial cancer w/ parametrial involvement

Answer 15

Stage IIB

Question 16

cervical cancer spread to pelvic side wall or hydronephrosis

Answer 16

Stage III

Question 17

cervical cancer tumor to lower 1/3 vagina but no side wall

Answer 17

Stage IIIA

Question 18

Cervical cancer to pelvic side wall or hydronephrosis

Answer 18

Stage IIIB

Question 19

Cervical cancer to lower 2/3 vagina

Answer 19

Stage IVA

Question 20

Tumor limited to one ovary

Answer 20

IA

Question 21

Tumor to both ovaries

Answer 21

1B

Question 22

Surgical spill

Answer 22

IC1

Question 23

capsule rupture prior to surg

Answer 23

1C2

Question 24

Malignant ascites of ovarian cancer

Answer 24

1C3

Question 25

Ovarian impants on uterus or tubes

Answer 25

Stage IIa

Question 26

implants on other intraperitoneal tissues - ovarian

Answer 26

Stage IIB

Question 27

Positive retroperitoneal nodes of OC

Answer 27

Stage IIIA

Question 28

Confirmed LN and spread to peritoneum outside pelvis - ovary

Answer 28

Stage III

Question 29

Ovarian Microscopic estraperitoneal involvement + RLN

Answer 29

Stage IIIA

Question 30

Ovarisan macroscopic <2cm extraperitoneal + R LN

Answer 30

Stage IIIB

Question 31

OVarian macroscopic >2cm extraperitoneal + RLN

Answer 31

Stage IIIC

Question 32

Pleural effusion - Ovarain

Answer 32

Stage IVA

Question 33

Distant mets - ovarian

Answer 33

Stage IVB

Question 34

Endometiral - tumor invasion to cervical stroma, but not beyond uterus

Answer 34

stage II

Question 35

Local or regional spread of tumor - endometrial

Answer 35

Stage III

Question 36

Tumor invades seroa or adnexa - endo

Answer 36

Stage IIIA

Question 37

Vagina of parametrial - endo

Answer 37

Stage IIIB

Question 38

Positive pelvic or paraaortic nodes - endo

Answer 38

Stage IIIC

Question 39

Mechanism of ifosfamide

Answer 39

attacks negative charged phosphate of NDA to cause cross linking and strand breaks

Question 40

Mechanism of methotrexate

Answer 40

interferes with metabolic process (folate) in making DNA

Question 41

Doxorubicin mechanism

Answer 41

free oxygen radicals to madage DNA and inhibit DNA synthesis

Question 42

Etoposide mechanism

Answer 42

topo II inhibitor - late S/G2

Question 43

Vincristine/vinblastine mechanism

Answer 43

inhibits mitotic spindle apparatus

Question 44

paclitaxel mechanism

Answer 44

high affininity of MT to inhibit normal fxn

Question 45

Cisplantin mchanism

Answer 45

crosslinks DNA

Question 46

Gemcitabine mechanism

Answer 46

Nucleotisde analog

Question 47

Gemcitabine SE

Answer 47

bone marrow suppression, hair loss

Question 48

side effects of pelvic radiation

Answer 48

diarrhea, rectal bleeding, fistula formation, urinary incontence, bladder irritation