Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Infectious Disease > SSTIs > Flashcards

SSTIs Flashcards

1
Q

Purulent SSTIs

A
  • Impetigo
  • Cutaneous abcesses
  • Inflamed epidermoid cysts
  • Furuncles
  • Carbuncles
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is Impetigo?

A
  • Highly contagious infection of epidermis
  • Typically transmitted through direct contact
  • Occurs most commonly in children
  • Most frequently affects face and extremities
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the two types of Impetigo?

A

Nonbullous (~70% of cases)
Bullous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the predisposing factors of Impetigo?

A
  • Group A Strep skin colonization or S. aureus nasal colonization.
  • Hot, humid summer weather
  • Areas with poor hygiene and in crowded living conditions
  • Minor trauma (insect bite, abrasion)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is Nonbullous Impetigo?

A
  • Caused by: Strep pyogenes (Group A) or Staph aureus
  • Small, fluid filled vesicles → pustules → pustules rupture → golden yellow crusts over an erythematous base
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is Bullous Impetigo?

A
  • Caused by: Staphylococcus aureus
  • Vesicles → bullae with clear, yellow fluid → bullae rupture, forming thin, light brown crusts
  • Usually affects neonates and children < 5 yo
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Ecthyma

A
  • Ulcerative form of impetigo causing painful fluid- or pus-filled sores; heals with scarring
  • Requires abx tx
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Topical Treatment of Impetigo

A
  • Topical therapy is as effective as systemic therapy
  • Mupirocin or retapamulin applied to lesions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Duration of Topical Treatment of Impetigo

A

5 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Systemic Treatment of Impetigo (suspicion or confirmation of MRSA)

A
  • Clindamycin
  • Doxycycline
  • TMP/SMX
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Systemic Treatment of Impetigo (no suspicion of MRSA)

A
  • Dicloxacillin
  • Cephalexin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Duration of Systemic Treatment of Impetigo

A

7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is Folliculitis?

A
  • Pyoderma located within hair follicles
  • Small (<5mm), erythematous (sometimes pruritic) papules usually covered by central pustule
  • Develops in areas of friction and perspiration (armpits, groin, etc.)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the causative organisms of Folliculitis?

A
  • S. aureus (most common)
  • P. aeruginosa (swimming pools, hot tubs, whirlpools)
  • Candida spp (prolonged antibiotics or corticosteroids)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the treatment for Folliculitis?

A
  • Saline compresses (promotes drainage)
  • Topical therapy with antibacterials or antifungals sufficient
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are Furuncles (Boils)?

A
  • Deep inflammatory nodule that typically develops from preceding folliculitis.
  • Lesions often rupture and drain spontaneously
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the treatment for Furuncles?

A

Application of moist heat to promote drainage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are Carbuncles?

A
  • When infection extends to involve several adjacent follicles producing a coalescing inflammatory mass with pus draining from multiple follicular orifices.
  • Progression from furuncles
  • Typically found at nape of neck, face, armpits, buttocks
  • Fever and malaise usually present
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the causative organism of Furuncles and Carbuncles?

A

S. aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are the predisposing factors for Furuncles and Carbuncles?

A
  • Diabetes, obesity
  • Inadequate personal hygiene
  • Close contact with others with furuncles
  • Anterior nares colonization with S. aureus (recurrent cases)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is the treatment for Furuncles and Carbuncles?

A
  • Incision and drainage (I&D)
  • Systemic antibiotics rarely required unless fever or multiple furuncles/carbuncles
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Causative Organism of Cutaneous Abcesses and Inflamed Epidermoid Cysts

A

S. aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Treatment of Cutaneous Abcesses and Inflamed Epidermoid Cysts

A
  • Incision and evacuation of pus and debris
  • Systemic antibiotics usually NOT recommended
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

When to use systemic abx for purulent SSTI

A
  • Systemic signs of infection (fever, etc.)
  • Multiple abcesses
  • Lack of response to I & D
  • Immunocompromised
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Duration of Systemic Abx Therapy for Purulent SSTI

A

5 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

When is MRSA coverage warranted for purulent SSTI?

A
  • Long-term care facility
  • IV drug abuse
  • HIV
  • MSM
  • Incarceration
  • Military
  • Native American
  • Sharing razors or sports equipment
  • History of MRSA infection/colonization
  • Current MRSA infection elsewhere
  • Failed initial abx therapy
  • Penetrating trauma
  • Markedly impaired host defenses
  • Severe infection with systemic sxs and/or hypotension
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Duration of Therapy for Purulent SSTI if concern for MRSA

A

5-7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

PO Antibiotics for MSSA Purulent SSTI

A
  • Dicloxacillin
  • Cephalexin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

IV Antibiotics for MSSA Purulent SSTI

A
  • Nafcillin/Oxacillin
  • Cefazolin
  • Clindamycin (if pt has beta-lactam allergy)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

PO Antibiotic Therapy for MRSA Purulent SSTI

A
  • Doxycycline
  • TMP/SMX
  • Clindamycin (need to do D-test first to check susceptibility)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

IV Antibiotics for MRSA Purulent SSTI

A
  • Vancomycin (DOC)
  • Linezolid
  • Ceftaroline
  • Daptomycin
  • Oritavancin (preferred for outpatient)
  • Dalbavancin (preferred for outpatient)
  • Tedizolid
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Treatment of Recurrent S. aureus SSTI

A
  • Nasal decolonization: Mupirocin 2% intranasal x 5-10 days
  • Topical decolonization: Chlorhexidine or bleach bath
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

What is Cellulitis?

A
  • Acute, spreading infection of skin that involves epidermis and dermis.
  • Local tenderness/pain, swelling, warmth, erythema
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

What is the location of Cellulitis?

A

Commonly on lower legs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

What are the systemic manifestations of Cellulitis?

A

Fever, tachycardia, confusion, hypotension, leukocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Erysipelas

A

Superficial form of cellulitis with clearly defined borders of inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

What are the predisposing factors for Cellulitis?

A
  • Previous trauma (laceration, puncture wound)
  • Conditions that cause skin to be more fragile or local host defenses less effective (obesity, diabetes, previous cutaneous damage, edema (from venous insufficiency or lymphatic obstruction), surgical procedures, eczema)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Common Pathogens Causing Cellulitis

A
  • S. pyogenes (Group A) - most common
  • S. aureus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

How to Differentiate Between Cellulitis Caused by S. pyogenes or S. aurues

A

S. aureus infection usually has pus, purulence, or abcess

S. pyogenes infection does not

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Diagnosis of Cellulitis

A
  • Done by physical exam
  • Routine diagnostic testing NOT recommended
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Symptoms of Mild Cellulitis

A
  • No purulence
  • No systemic sxs, AMS, or hemodynamic instability
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Treatment of Mild Cellulitis

A
  • Outpatient tx
  • Penicillin
  • Augmentin
  • Cephalexin
  • Clindmycin (if beta-lactam allergy)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Signs/Symptoms of Mederate-Severe Cellulitis

A
  • Deeper infection
  • Poor adherence
  • Systemic sxs
  • Failed outpatient therapy
  • Immunocompromised
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Treatment of Moderate-Severe Cellulitis

A
  • Inpatient tx
  • Penicillin IV
  • Cefazolin or ceftriaxone
  • Clindamycin (if beta-lactam allergy)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Duration of Cellulitis Treatment (regardless of severity)

A

5 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

When is MRSA coverage indicated for cellulitis?

A
  • Penetrating trauma
  • Evidence of MRSA infection elsewhere
  • Nasal colonization with MRSA
  • Injection drug use
  • Purulent drainage
  • Severe infection (necrotizing)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

PO Treatment for MRSA Cellulitis

A
  • TMP/SMX
  • Doxycycline
  • Clindamycin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

IV treatment for MRSA Cellulitis

A
  • Vancomycin (DOC)
  • Linezolid
  • Daptomycin
  • Ceftaroline
  • Tigecycline
  • Telavancin
  • Tedizolid
  • Oritavancin
  • Dalbavancin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

Cellulitis Treatment if Coverage for Strep and MRSA Needed

A
  • Clindamycin
  • TMP/SMX + Beta-Lactam
  • Doxycycline + Beta-Lactam
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

Non-Medication therapy for Cellulitis

A

Elevation of affected area

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

Adjunctive Treatment for Cellulitis

A

Systemic corticosteroids x 7 days in non-diabetic adults

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

Recurrent Cellulitis

A
  • 2+ discrete SSTIs over a 6 month period
  • 3-4 SSTIs/year
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

Prophylactic antibiotics for Recurrent Cellulitis

A
  • Penicillin V
  • Erythromycin
  • Benzathine penicillin
54
Q

Duration of Cellulitis Prophylaxis

A

Continue therapy for as long as predisposing factors are present

55
Q

What is some general information about Bite Wounds?

A
  • Most bites are due to dogs or cats
  • Cat bite wounds are usually more severe and have higher proportion of osteomyelitis and septic arthritis
  • Human bite wounds are typically more serious than animal bites
  • Predominant pathogens: oral flora, skin flora
56
Q

What are the complications caused by bite wounds?

A

Septic arthritis, osteomyelitis, subcutaneous abscess formation, tendonitis, bacteremia (rarely)

57
Q

What is the bacteriology of Dog/Cat bite wounds?

A
  • Pasteurella - most common
  • Capnocytophaga canimorsus: causes bacteremia and fatal sepsis especially in asplenia or underlying hepatic disease patients
58
Q

What is the bacteriology of Human bite wounds?

A
  • Strep (esp. viridans)
  • Staph
  • Eikenella corrodens - most common
  • Anaerobes present in > 60% of cases
59
Q

What are some vaccines that can be used for Bite Wounds?

A

Tetanus. Rabies (for all feral, wild animal bites, areas with high prevalence of rabies)

60
Q

Drug of Choice for Treatment of Bite Wounds

A

Beta-lactam + Beta-lactamase inhibitor

  • Augmentin
  • Ampicillin/sulbactam
  • Piperacillin/tazobactam
61
Q

When should IV therapy be used for bite wounds?

A
  • Failed initial oral abx
  • Bite involves hand, head, joint
  • Presence of lymphatic spread
62
Q

Bite Wound Treatment (beta-lactam allergy)

A

2nd or 3rd generation cephalosporin, TMP/SMX, levofloxacin, ciprofloxacin

PLUS

Metronidazole

OR

Single-Agent Options: carbapenem, moxifloxacin, doxycycline

63
Q

Duration of Treatment for Bite Wounds

A

5 days

64
Q

What should be avoided in the treatment of Bite Wounds?

A

1st generation CEPHs and Penicillinase-Resistant PCNs (oxacillin, nafcillin, dicloxacillin), Macrolides, Clindamycin

65
Q

Wound closure for Bite Wounds

A

Wound closure is NOT recommended unless affected area involves face

66
Q

What are Necrotizing Skin and Soft Tissue Infections?

A
  • Aggressive subcutaneous infection of the fascial and/or muscle compartments
  • Can cause major tissue destruction and death
  • Usually develops from an initial skin break from trauma or surgery
  • Life threatening emergency - requires surgery and broad spectrum abx
67
Q

What are the clinical features of Necrotizing Fasciitis

A
  • Severe pain disproportional to clinical findings
  • Hard, wooden feel of subcutaneous tissue
  • Crepitus (including gas in tissue)
68
Q

Type II (Monomicrobial) Necrotizing Fasciitis

A
  • Commonly affects lower extremities
  • Common cause: S. pyogenes
69
Q

Type I (Polymicrobial) Necrotizing Fasciitis

A
  • Common in IV drug users (at injection site)
  • Originates from bowel or genitourinary flora
  • Polymicrobial: average of 5 pathogens per wound
70
Q

Diagnosis of Necrotizing Fasciitis

A
  • Definitive diagnosis via surgical exploration
  • Culture and gram stain of deep tissue sample from surgery
71
Q

Treatment of Necrotizing Fasciitis

A

Emergent surgery intervention followed by debridement every 24-36 hours

72
Q

Empiric Therapy for Nectrotizing Fasciitis

A
  • Broad spectrum (including MRSA and anaerobes)
  • Vanco PLUS piperacillin/tazobactam (or carbapenem)
73
Q

Directed Therapy for Necrotizing Fasciitis (Strep)

A

PCN + clindamycin

74
Q

Directed Therapy for Necrotizing Fasciitis (Staph)

A
  • MSSA: 1st generation cephalosporin or oxacillin
  • MRSA: Vanco
75
Q

Duration of Treatment for Necrotizing Fasciitis

A

Until debridement is no longer necessary

76
Q

Clinical Features of Infectious Gangrene

A
  • Gas production leading to crepitus
  • Muscle necrosis
  • Progression within hours
77
Q

What is Trauma-Associated Clostridial Gas Gangrene?

A
  • C. perfringens most frequent cause
  • Skin initially pale –> bronze –> purplish red.
  • Signs of systemic toxicity: tachycardia, fever, diaphoresis –> shock and multiple organ failure
78
Q

What is Spontaneous Clostridial Gas Gangrene?

A
  • C. septicum most frequent cause
  • Neutropenic and GI malignancy patients
79
Q

Diagnosis of Infectious Gangrene

A

Diagnosis by surgical exploration during emergent debridement

80
Q

Treatment of Infectious Gangrene

A

Emergent surgical debridement + appropriate abx

81
Q

Empiric Antibiotic Therapy for Infectious Gangrene

A
  • Broad spectrum (including MRSA and anaerobes)
  • Vanco PLUS piperacillin/tazobactam
82
Q

Directed Antibiotic Therapy for Infectious Gangrene (Clostridial)

A

PCN + Clindamycin

83
Q

What are the general characteristics of Diabetic Foot Infections?

A

Usually arise from a skin ulceration that occurs as a consequence of peripheral neuropathy or wound from trauma

84
Q

Risk Factors for Diabetic Foot Infections

A
  • Peripheral neuropathy
  • Peripheral vascular disease
  • Poor glycemic control
  • Foot deformities
  • Ulcer present > 30 days
  • History of recurrent foot infections
  • Previous lower extremity amputation
  • Walking barefoot
85
Q

Diagnosis for Diabetic Foot Infections

A

Purulent secretions OR

2 classic signs or symptoms of inflammation: erythema, warmth, tenderness, pain, or induration

Definitive Diagnosis: culture and sensitivity

MRI to rule out abscess or osteomyelitis

Labs - WBC, ESR, CRP, Procal

86
Q

What organisms cause the acute/superficial (typically monomicrobial) diabetic foot infections?

A
  • S. aureus
  • S. epidermidis
  • Beta-hemolytic strep (Group A, B, C, G)
87
Q

What organisms cause chronic/deep (typically polymicrobial) diabetic foot infections?

A
  • S. aureus
  • Strep
  • Enterococcus
  • Enterobacteriaceae
  • Pseudomonas
  • Anaerobes
88
Q

What organisms cause necrosis, gangrene, or malodorous drainage in diabetic foot infections?

A
  • Anaerobic Strep
  • Bacteroides
  • Clostridium
89
Q

Mild Diabetic Foot Infection

A
  • Local infection
  • Erythema 0.5-2 cm
90
Q

Moderate Diabetic Foot Infection

A
  • Local infection
  • Erythema > 2 cm
  • Deeper infections
91
Q

Severe Diabetic Foot Infection

A

Local infection with systemic signs of infection

92
Q

Diabetic Foot Infections Requiring Hospitalization

A
  • Severe infection
  • Moderate infection with complicating features (severe PAD, poor social support)
  • Poor compliance with or failing outpatient therapy
93
Q

Treatment of Diabetic Foot Infections

A

Debridement, proper wound care, + appropriate abx

94
Q

Uninfected diabetic foot ulcers

A

Avoid antibiotic use

95
Q

Mild-moderate diabetic foot infections

A
  • Narrow spectrum agent: aerobic GPC coverage
  • High bioavailability PO agents may be sufficient (Augmentin)
96
Q

Severe or chronic diabetic food infections

A
  • Broad spectrum agents: GPC (+MRSA), GNR, anaerobes
  • Vanco PLUS Zosyn, Carbapenem, Cefepime, Ceftazidime, or Aztreonam
  • Parenteral therapy (may switch to PO when stable)
97
Q

Duration of treatment be for mild diabetic foot infections

A

1-2 weeks

98
Q

Treatment duration for moderate-severe diabetic foot infections

A

2-3 weeks

99
Q

Wound care for diabetic foot infections

A
  • Dressed in a manner that allows daily inspection and encourages a moist wound-healing environment.
  • Removal of pressure from foot wound is necessary for healing.
  • Accuzyme: topical debriding agent
100
Q

Need for surgery with diabetic foot infections

A

-I/D of necrotic tissue

Revascularization of lower extremity

-Urgent amputation for extensive necrosis or life-threatening infection

101
Q

What is Osteomyelitis?

A
  • Progressive infectious process that can involve one or multiple components of bone
  • Characterized by inflammatory destruction of bone, necrosis, and new bone formation
102
Q

Signs and Symptoms of Osteomyelitis

A
  • Dull pain at involved site
  • Local inflammation (tenderness, warmth, erythema, swelling)
  • Systemic symptoms may be present
103
Q

Cierny and Mader Stage 1

A
  • Medullary: likely seen on MRI
  • Hematogenous seeding
  • Can be treated with antimicrobial therapy alone
104
Q

Cierny and Mader Stage 2

A
  • Superficial
  • Contiguous spread
  • Requires surgical intervention + systemic abx
105
Q

Cierny and Mader Stage 3

A
  • Localized
  • Hematogenous or contiguous
  • Requires surgical intervention + systemic abx
  • Resection required
106
Q

What is Cierny and Mader Stage 4?

A
  • Diffuse osteo
  • Requires surgical intervention + systemic abx
  • Resection required
107
Q

How is Osteomyelitis diagnosed?

A

Confirmation by imaging studies +/- growth of microorganism from bone biopsy or surgical sampling

108
Q

What labs are abnormal in Osteomyelitis?

A

ESR and CRP elevated

109
Q

What imaging studies are done for Osteomyelitis?

A

X-ray: quickest

MRI: gold-standard

110
Q

Acute Osteomyelitis

A
  • Onset: days to weeks
  • Necrotic bone usually absent
111
Q

Chronic Osteomyelitis

A
  • Onset: weeks to months (may persist for years)
  • Necrotic bone present
112
Q

Age of Onset for Contiguous Osteomyelitis

A

Adults > 50 yo

113
Q

What is the age of onset like for Osteomyelitis due to vascular insufficiency?

A

Adults > 40 years

114
Q

What is the age of onset like for Hematogenous Osteomyelitis?

A

Mostly in children (age < 20 yrs), adults > 50 yrs

115
Q

Sites of Infection in Contiguous Osteomyelitis

A

Femur, tibia, skull, mandible

116
Q

What are the sites of infections for Contiguous Osteomyelitis?

A

Femur, tibia, skull, mandible

117
Q

What are the sites of infections for Hematogenous Osteomyelitis?

A

Long bones (tibia and femur) in children

Vertebrae (spondylodiskitis) in adults

118
Q

What are the risk factors for Contiguous Osteomyelitis?

A
  • Trauma
  • Surgery
  • Insertion of joint prosthesis
  • Cellulitis
119
Q

What are the risk factors for Osteomyelitis due to vascular insufficiency?

A
  • DM > 10 yrs
  • Poor glucose control
  • Peripheral neuropathy
  • Peripheral vascular disease
120
Q

What are the risk factors for Hematogenous Osteomyelitis?

A

Bacteremia or endocarditis

121
Q

What are the typical microorganisms that cause Contiguous Osteomyelitis?

A

Usually polymicrobial

Most common: S. aureus

122
Q

What are the typical microorganisms that cause Osteomyelitis due to vascular insufficiency?

A

Usually polymicrobial

Most common: S. aureus and Beta-Hemolytic Strep

123
Q

What are the typical microorganisms that cause Hematogenous Osteomyelitis?

A

Usually monomicrobial

Neonates: S. aureus, Group B Strep, E. coli

Children: S. aureus and S. pneumoniae

Adults: S. aureus and S. epidermidis

Elderly: GNRs

IVDU: P. aeruginosa

124
Q

Duration of Antimicrobial Therapy for Osteomyelitis (no surgical intervention)

A

At least 6 weeks of IV abx

125
Q

Duration of Antimicrobial Therapy for Osteomyelitis (following radical resection of infected tissue of diabetic foot osteomyelitis)

A

2-5 days

126
Q

Duration of Antimicrobial Therapy for Osteomyelitis (persistent infected or necrotic bone)

A

At least 4 weeks

127
Q

Duration of Antimicrobial Therapy for Osteomyelitis (acute, hematogenous infection)

A

At least 4-6 weeks of IV abx

128
Q

Duration of Antimicrobial Therapy for Osteomyelitis (chronic infection)

A

Months (IV followed by PO)

129
Q

What is the treatment for Hematogenous osteomyelitis like?

A
  • S. aureus: cefazolin or oxacillin
  • MRSA or S. epidermidis: Vancomycin
  • GNB: 3rd gen ceph
130
Q

What is the treatment for Contiguous or vascular insufficiency osteomyelitis like?

A
  • Polymicrobial: Pip/tazo OR 3rd gen ceph + metronidazole or clindamycin
  • Pseudomonas coverage: Pip/tazo, Ceftazidime or cefepime, Ciprofloxacin

Infectious Disease (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions