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Infectious Disease > Duncan Basics of Fungal Organisms > Flashcards

Duncan Basics of Fungal Organisms Flashcards

1
Q

Prokaryote vs Eukaryote

A

Prokaryote lacks a cell nucleus

Eukaryote has a cell nucleus

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2
Q

Do archaea cause disease in humans?

A

No

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3
Q

Are fungi prokaryotes or eukaryotes?

A

Eukaryotes

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4
Q

Important Characteristics of Fungi

A

Cell wall
Cell membrane
Nucleus

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5
Q

Fungal Cell Wall

A

Made up of chitin

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6
Q

Fungal Cell Membrane

A

Contains ergosterol

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7
Q

Types of Fungi

A

Yeasts
Molds
Dimorphic Fungi

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8
Q

Yeasts

A

A fungal cell growing in isolation from others as a single cell

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9
Q

Molds

A

Multicellular organism

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10
Q

Dimorphic Fungi

A

Mold in the cold, yeast in the heat

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11
Q

Septate Fungi

A

Individual cells retain their cell membranes

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12
Q

Nonseptate Fungi

A

Multiple nuclei in a single cytoplasm

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13
Q

Fungal Reproduction

A

Fungi can switch back and forth between asexual and sexual reproduction
Asexual - budding/haploid
Sexual - mating/diploid

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14
Q

When do fungi switch to asexual reproduction?

A

When they are under stress

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15
Q

Fungal Metabolism

A

Cannot photosynthesize, must obtain carbon food from environment

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16
Q

Fungal Energy Production

A

Mitochondria for aerobic respiration

17
Q

What is chitin made up of?

A

N-acetyl glucosamine (NAG)

18
Q

Fungal Ribosome

A

60S - large subunit
40S - small subunit
Contains peptidyl transferase center

19
Q

Have fungal toxins been used to create new drugs?

A

Yes, ergot toxin is used to make ergot derivative drugs to treat migraine

20
Q

Fungal Diagnosis

A

Microscopic examination (KOH, special stains)
Culture (Sabouraud’s agar)
DNA-based tests - PCR
Serologic tests - antibody testing

21
Q

Main way fungi get into the body to cause systemic infection

A

Inhalation

22
Q

Neutrophil to Macrophage Response to Aspergillus

A

Infectious Disease (15 decks)

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