SSRIs

Question 1

What are the common SSRIs drugs?

Answer 1

Citalopram (Celexa)
Escitalopram (Lexapro)
Fluoxetine (Prozac)
Paroxetine (Paxil)
Sertraline (Zoloft)
Vilazodone (Viibryd)

Question 2

What are the expected pharmacological action?

Answer 2

Selectively block reuptake of the monoamine neurotransmitters serotonin in the synaptic space, thereby intensifying the effects of serotonin.

Question 3

Therapeutic uses?

Answer 3

Major Depression
OCD (Obsessive compulsive disorder)
Bulimia nervosa
Panic disorders
PTSD

Question 4

Common adverse effects?

Answer 4

CNS stimulation (insomnia, agitation, tremors, anxiety)
Serotonin syndrome
Sexual dysfunction

However, side effects are low, and therefore, are considered the first line of treatment.

Question 5

What are the common contraindications and precautions

Answer 5

Contraindicated for concurrent use of MAOIs and TCAs.

Not to use Fluoxetine (Prozac) and Paroxetine (Paxil) when pregnant.