Squamous Cell Lung Cancer Flashcards

1
Q

What % of NSCLC does squamous cell lung cancer make up?

A

About 25%

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2
Q

Where do they typically tend to be located?

A

Centrally

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3
Q

Where does squamous cell cancer typically arise? How do they typically extend?

A

Typically from the segmental bronchi and involve lobar and mainstem bronchi by extension.

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4
Q

What are the typical histologic features?

A

Squamous pearl formation, intercellular bridging, and individual cell keratinization.

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5
Q

When are mutations testing in squamous cell lung cancer and what are they?

A

If patient is never smoker or light smoking should test for ALK or EGFR.

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