Squamous Cell Carcinoma

Question 1

Squamous cell carcinoma

Answer 1

Arises from superficial layers of epidermis
More aggressive than BCC
Appearance:
Irregular
Red plaque
Scaly or warty
Ulceration
Invasion
Infection

Question 2

Squamous cell carcinoma (II)

Answer 2

Low rate of metastases through spread to lymph nodes more common than BCC
Most common on face
Presents as an irregular keratinous nodule or firm erythematous plaque
Freq ulcerates

Question 3

Acting keratosis

Answer 3

Rough areas of skin found in people who have been exposed to a lot of sun
Very common in 1/3 men 70+ have at least 1 actinic keratosis
Approx 2% will turn into SCC

Question 4

Bowmen’s disease (ça in situ)

Answer 4

Early form SCC
Cancerous cells spread along skins surface but usually slow growing may not change for years only occasionally 3-5%

Question 5

Malignant melanoma

Answer 5

Malignant transformation of melanocytes in stratum basalt of epidermis
Most occur in skin though may originate from other sites
Subtypes- superficial 70cases
Nodular- 20%
Actual lentigous- 5%
Lentigo maligna melanoma- 5%

Question 6

Superficial spreading

Answer 6

70% of cases
Darker area in pre-existing mile
Irregular edge and colour variation

Question 7

Nodular

Answer 7

Most aggressive
Grows quickly on normal skin
Blue/black in colour
Dome shaped

Question 8

Acral lentiginous melanoma

Answer 8

Common with black ethnicity
Palms, soles and under nails
Large and aggressive lesions
Late lesions have rapid vertical growth phase